An E2F binding-deficient Rb1 protein partially rescues developmental defects associated with Rb1 nullizygosity (Q34353676)

1 August 2017

title

An E2F binding-deficient Rb1 protein partially rescues developmental defects associated with Rb1 nullizygosity (English)

1 reference

1 August 2017

Huifang Sun

1

1 reference

1 August 2017

Yanjie Chang

2

1 reference

1 August 2017

Brett Schweers

3

1 reference

1 August 2017

Michael A Dyer

4

1 reference

1 August 2017

Xiaojing Zhang

5

1 reference

1 August 2017

Simon W Hayward

6

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1 August 2017

David W Goodrich

7

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1 August 2017

language of work or name

English

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publication date

1 February 2006

1 reference

Molecular and Cellular Biology

1 August 2017

published in

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1 August 2017

volume

26

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1 August 2017

issue

4

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1 August 2017

page(s)

1527-1537

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Perspective: new genetic tools for studying retinal development and disease

1 August 2017

cites work

1 reference

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6 July 2018

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Human hHpr1/p84/Thoc1 regulates transcriptional elongation and physically links RNA polymerase II and RNA processing factors

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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The E2F1-3 transcription factors are essential for cellular proliferation.

6 July 2018

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6 July 2018

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p107 and p130: versatile proteins with interesting pockets

6 July 2018

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E2F3 contributes both to the inappropriate proliferation and to the apoptosis arising in Rb mutant embryos

6 July 2018

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The p57Kip2 cyclin kinase inhibitor is expressed by a restricted set of amacrine cells in the rodent retina

6 July 2018

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Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization

6 July 2018

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Loss of E2F4 activity leads to abnormal development of multiple cellular lineages

6 July 2018

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E2F4 is essential for normal erythrocyte maturation and neonatal viability

6 July 2018

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Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum

6 July 2018

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Mutagenesis of the pRB pocket reveals that cell cycle arrest functions are separable from binding to viral oncoproteins

6 July 2018

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Temperature-sensitive RB mutations linked to incomplete penetrance of familial retinoblastoma in 12 families

6 July 2018

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The role of Ets family transcription factor PU.1 in hematopoietic cell differentiation, proliferation and apoptosis

6 July 2018

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pRB plays an essential role in cell cycle arrest induced by DNA damage

6 July 2018

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Growth suppression by an E2F-binding-defective retinoblastoma protein (RB): contribution from the RB C pocket

6 July 2018

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Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth

6 July 2018

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Incomplete penetrance of familial retinoblastoma linked to germ-line mutations that result in partial loss of RB function

6 July 2018

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Transcription of the E2F-1 gene is rendered cell cycle dependent by E2F DNA-binding sites within its promoter

6 July 2018

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Distinct RB1 gene mutations with low penetrance in hereditary retinoblastoma

6 July 2018

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Developmental rescue of an embryonic-lethal mutation in the retinoblastoma gene in chimeric mice

6 July 2018

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Extensive contribution of Rb-deficient cells to adult chimeric mice with limited histopathological consequences

6 July 2018

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The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle

6 July 2018

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Requirement for a functional Rb-1 gene in murine development

6 July 2018

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Effects of an Rb mutation in the mouse

6 July 2018

1 reference

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Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

6 July 2018

1 reference

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Oncogenic point mutations in exon 20 of the RB1 gene in families showing incomplete penetrance and mild expression of the retinoblastoma phenotype

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1367194

Retinoblastoma protein acts as Pax 8 transcriptional coactivator.

6 July 2018

1 reference

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Developmental defects in Rb-deficient retinae

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1367194

Rb regulates proliferation and rod photoreceptor development in the mouse retina

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1367194

Extra-embryonic function of Rb is essential for embryonic development and viability

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1367194

E2F4 loss suppresses tumorigenesis in Rb mutant mice.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1367194

Specificity of E2F1, E2F2, and E2F3 in mediating phenotypes induced by loss of Rb.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1367194

Role of LXCXE motif-dependent interactions in the activity of the retinoblastoma protein

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1367194

The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1367194

p27Kip1 and p57Kip2 regulate proliferation in distinct retinal progenitor cell populations.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1367194

PREPARATION OF FATTY ACID METHYL ESTERS AND DIMETHYLACETALS FROM LIPIDS WITH BORON FLUORIDE--METHANOL

27 October 2018

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12 December 2020

Genomic analysis of mouse retinal development

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12 December 2020

Targeted disruption of p107: functional overlap between p107 and Rb

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12 December 2020

Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos

1 reference

12 December 2020

10.1128/MCB.26.4.1527-1537.2006

Identifiers

DOI

1 reference

1 August 2017

1 reference

1 August 2017

1 reference