Cyclic nucleotide-gated channels: shedding light on the opening of a channel pore (Q34354389)

1 August 2017

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title

Cyclic nucleotide-gated channels: shedding light on the opening of a channel pore (English)

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1 August 2017

G E Flynn

1

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1 August 2017

J P Johnson

series ordinal

2

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1 August 2017

W N Zagotta

series ordinal

3

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1 August 2017

language of work or name

English

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publication date

1 September 2001

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Nature Reviews Neuroscience

1 August 2017

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1 August 2017

2

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1 August 2017

9

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1 August 2017

643-651

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https://scigraph.springernature.com/pub.10.1038/35090015

1 August 2017

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cites work

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Primary structure and functional expression of a cyclic nucleotide-activated channel from olfactory neurons

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Primary structure of cAMP-gated channel from bovine olfactory epithelium

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Molecular cloning and single-channel properties of the cyclic nucleotide-gated channel from catfish olfactory neurons.

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Rod and cone photoreceptor cells express distinct genes for cGMP-gated channels.

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A second subunit of the olfactory cyclic nucleotide-gated channel confers high sensitivity to cAMP

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A 240 kDa protein represents the complete beta subunit of the cyclic nucleotide-gated channel from rod photoreceptor

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Molecular cloning and functional characterization of a new modulatory cyclic nucleotide-gated channel subunit from mouse retina

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Cyclic GMP-activated channel activity in renal epithelial cells (A6).

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Primary structure and functional expression of a cyclic nucleotide-gated channel from rabbit aorta.

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Another member of the cyclic nucleotide-gated channel family, expressed in testis, kidney, and heart

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Expression of cyclic nucleotide-gated cation channels in non-sensory tissues and cells

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Cloning and functional expression of a cyclic-nucleotide-gated channel from mammalian sperm

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Two alternatively spliced forms of the cGMP-gated channel alpha-subunit from cone photoreceptor are expressed in the chick pineal organ.

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Exposure of residues in the cyclic nucleotide-gated channel pore: P region structure and function in gating

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Cyclic nucleotide-gated channels. Pore topology studied through the accessibility of reporter cysteines

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Change of pore helix conformational state upon opening of cyclic nucleotide-gated channels.

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Conformational changes in S6 coupled to the opening of cyclic nucleotide-gated channels

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Rotational movement during cyclic nucleotide-gated channel opening

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How does the W434F mutation block current in Shaker potassium channels?

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Macroscopic Na+ currents in the "Nonconducting" Shaker potassium channel mutant W434F.

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Role of H5 domain in determining pore diameter and ion permeation through cyclic nucleotide-gated channels.

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A Functional Connection Between the Pores of Distantly Related Ion Channels as Revealed by Mutant K + Channels

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A single negative charge within the pore region of a cGMP-gated channel controls rectification, Ca2+ blockage, and ionic selectivity

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Two identical noninteracting sites in an ion channel revealed by proton transfer

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Divalent cation selectivity in a cyclic nucleotide-gated ion channel.

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Isolation of a single carboxyl-carboxylate proton binding site in the pore of a cyclic nucleotide-gated channel

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A point mutation in the pore region alters gating, Ca(2+) blockage, and permeation of olfactory cyclic nucleotide-gated channels

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Conductance and kinetics of single cGMP-activated channels in salamander rod outer segments

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Divalent cation selectivity is a function of gating in native and recombinant cyclic nucleotide-gated ion channels from retinal photoreceptors

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Sodium ions selectively eliminate the fast component of guanosine cyclic 3',5'-phosphate induced Ca2+ release from bovine rod outer segment disks.

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Single-channel study of the cGMP-dependent conductance of retinal rods from incorporation of native vesicles into planar lipid bilayers

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Tetracaine reports a conformational change in the pore of cyclic nucleotide-gated channels

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Mechanism of tetracaine block of cyclic nucleotide-gated channels

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Time-dependent current decline in cyclic GMP-gated bovine channels caused by point mutations in the pore region expressed in Xenopus oocytes

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Interaction of Tetraethylammonium Ion Derivatives with the Potassium Channels of Giant Axons

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Immobilisation of gating charge by a substance that simulates inactivation.

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Ion effects on gating of the Ca(2+)-activated K+ channel correlate with occupancy of the pore

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7 January 2021

Structural rearrangements underlying K+-channel activation gating

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7 January 2021

Selectivity changes during activation of mutant Shaker potassium channels

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Probing ion permeation and gating in a K+ channel with backbone mutations in the selectivity filter.

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Flexibility of the Kir6.2 inward rectifier K(+) channel pore

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Architecture of a K+ channel inner pore revealed by stoichiometric covalent modification.

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Coupling Gbetagamma-dependent activation to channel opening via pore elements in inwardly rectifying potassium channels

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Yeast screen for constitutively active mutant G protein-activated potassium channels

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7 January 2021

Block of the cGMP-gated cation channel of catfish rod and cone photoreceptors by organic cations

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7 January 2021

Potassium channel inactivation peptide blocks cyclic nucleotide-gated channels by binding to the conserved pore domain.

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7 January 2021

Localization of regions affecting an allosteric transition in cyclic nucleotide-activated channels.

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7 January 2021

A histidine residue associated with the gate of the cyclic nucleotide-activated channels in rod photoreceptors

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7 January 2021

Direct activation of the olfactory cyclic nucleotide-gated channel through modification of sulfhydryl groups by NO compounds.

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7 January 2021

Altered ligand specificity by protonation in the ligand binding domain of cyclic nucleotide-gated channels.

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7 January 2021

Direct interaction between amino- and carboxyl-terminal domains of cyclic nucleotide-gated channels

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7 January 2021

Movement of gating machinery during the activation of rod cyclic nucleotide-gated channels

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7 January 2021

Three amino acids in the C-linker are major determinants of gating in cyclic nucleotide-gated channels

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7 January 2021

C-Linker of cyclic nucleotide-gated channels controls coupling of ligand binding to channel gating

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7 January 2021

Gating rearrangements in cyclic nucleotide-gated channels revealed by patch-clamp fluorometry.

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7 January 2021

Subunit interactions in coordination of Ni2+ in cyclic nucleotide-gated channels

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7 January 2021

Improvements in protein secondary structure prediction by an enhanced neural network

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7 January 2021

Molecular architecture of full-length KcsA: role of cytoplasmic domains in ion permeation and activation gating

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7 January 2021

Structure of the gating domain of a Ca2+-activated K+ channel complexed with Ca2+/calmodulin

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Structure of the MscL homolog from Mycobacterium tuberculosis: a gated mechanosensitive ion channel

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7 January 2021

Constraining ligand-binding site stoichiometry suggests that a cyclic nucleotide-gated channel is composed of two functional dimers.

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7 January 2021

Stoichiometry and arrangement of subunits in rod cyclic nucleotide-gated channels.

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7 January 2021

A functioning chimera of the cyclic nucleotide-binding domain from the bovine retinal rod ion channel and the DNA-binding domain from catabolite gene-activating protein

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7 January 2021

Structure of the RCK domain from the E. coli K+ channel and demonstration of its presence in the human BK channel

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7 January 2021

Gating of retinal rod cation channel by different nucleotides: Comparative study of unitary currents

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7 January 2021

Interactions between divalent cations and the gating machinery of cyclic GMP-activated channels in salamander retinal rods

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7 January 2021

Structure of a complex of catabolite gene activator protein and cyclic AMP refined at 2.5 A resolution

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7 January 2021

Molecular code for cooperativity in hemoglobin

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7 January 2021

Control of ligand specificity in cyclic nucleotide-gated channels from rod photoreceptors and olfactory epithelium

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7 January 2021

Molecular mechanism for ligand discrimination of cyclic nucleotide-gated channels

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7 January 2021

Predicted ligand interactions of 3'5'-cyclic nucleotide-gated channel binding sites: comparison of retina and olfactory binding site models

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7 January 2021

Allosteric activation and tuning of ligand efficacy in cyclic-nucleotide-gated channels

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7 January 2021

Three residues predicted by molecular modeling to interact with the purine moiety alter ligand binding and channel gating in cyclic nucleotide-gated channels

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7 January 2021

Molecular rearrangements in the ligand-binding domain of cyclic nucleotide-gated channels

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7 January 2021

Sequence of events underlying the allosteric transition of rod cyclic nucleotide-gated channels

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7 January 2021

Mechanism of allosteric modulation of rod cyclic nucleotide-gated channels

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7 January 2021

Gated access to the pore of a voltage-dependent K+ channel

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7 January 2021

Blocker protection in the pore of a voltage-gated K+ channel and its structural implications

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7 January 2021

SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

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7 January 2021

Identifiers

DOI

10.1038/35090015

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Dimensions Publication ID

1 August 2017

1038282156

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Fatcat ID

release_z6qk4aclovajnoernqa6sjmh3q

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Fatcat

https://api.fatcat.wiki/v0/release/z6qk4aclovajnoernqa6sjmh3q

24 November 2022

mapped directly with Wikidata item

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