Engineering novel biocatalytic routes for production of semisynthetic opiate drugs (Q34355605)

1 August 2017

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title

Engineering novel biocatalytic routes for production of semisynthetic opiate drugs (English)

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1 August 2017

Boonstra B

1

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1 August 2017

Rathbone DA

series ordinal

2

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1 August 2017

Bruce NC

series ordinal

3

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1 August 2017

publication date

1 September 2001

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1 August 2017

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1 August 2017

volume

18

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1 August 2017

issue

2

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1 August 2017

page(s)

41-47

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Morphine Synthesis and Biosynthesis-An Update

1 August 2017

cites work

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Purification and characterization of NAD-dependent morphine 6-dehydrogenase from hamster liver cytosol, a new member of the aldo-keto reductase superfamily

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Identification of transformation products arising from bacterial oxidation of codeine by Streptomyces griseus.

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Microbial degradation of the morphine alkaloids: identification of morphine as an intermediate in the metabolism of morphine by Pseudomonas putida M10

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Transformations of morphine alkaloids by Pseudomonas putida M10

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Transformations of codeine to important semisynthetic opiate derivatives by Pseudomonas putida m10.

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Biological synthesis of the analgesic hydromorphone, an intermediate in the metabolism of morphine, by Pseudomonas putida M10

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Microbial degradation of the morphine alkaloids. Purification and characterization of morphine dehydrogenase from Pseudomonas putida M10.

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Bacterial morphine dehydrogenase further defines a distinct superfamily of oxidoreductases with diverse functional activities

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Nucleotide sequence and over-expression of morphine dehydrogenase, a plasmid-encoded gene from Pseudomonas putida M10.

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Towards engineering pathways for the synthesis of analgesics and antitussives.

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Purification and characterization of morphinone reductase from Pseudomonas putida M10.

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Bacterial morphinone reductase is related to Old Yellow Enzyme

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Crystallization and preliminary diffraction studies of morphinone reductase, a flavoprotein involved in the degradation of morphine alkaloids.

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7 January 2021

Reductive and oxidative half-reactions of morphinone reductase from Pseudomonas putida M10: a kinetic and thermodynamic analysis

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7 January 2021

Mechanistic studies of morphine dehydrogenase and stabilization against covalent inactivation

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An amperometric opiate assay

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Bioluminescent assay for heroin and its metabolites

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Biological production of semisynthetic opiates using genetically engineered bacteria

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Redesign of the coenzyme specificity of a dehydrogenase by protein engineering

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Determinants of cofactor specificity in isocitrate dehydrogenase: structure of an engineered NADP+ --> NAD+ specificity-reversal mutant

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7 January 2021

Cofactor regeneration by a soluble pyridine nucleotide transhydrogenase for biological production of hydromorphone

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7 January 2021

Cloning, sequence, and properties of the soluble pyridine nucleotide transhydrogenase of Pseudomonas fluorescens

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7 January 2021

Cloning, DNA sequencing and expression of (3-17)beta hydroxysteroid dehydrogenase from Pseudomonas testosteroni

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7 January 2021

Industrial biocatalysis today and tomorrow

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7 January 2021

10.1016/S1389-0344(01)00084-3

Identifiers

DOI

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1 August 2017

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