Zidovudine exposure in HIV-1 infected Tanzanian women increases mitochondrial DNA levels in placenta and umbilical cords (Q34358732)

1 August 2017

title

Zidovudine exposure in HIV-1 infected Tanzanian women increases mitochondrial DNA levels in placenta and umbilical cords (English)

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1 August 2017

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Andrea Kunz

1

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1 August 2017

Nicole von Wurmb-Schwark

2

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1 August 2017

Julius Sewangi

3

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1 August 2017

Judith Ziske

4

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1 August 2017

Inga Lau

5

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1 August 2017

Paulina Mbezi

6

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1 August 2017

Stefanie Theuring

7

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1 August 2017

Andrea Hauser

8

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1 August 2017

Festo Dugange

9

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1 August 2017

Angela Katerna

10

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1 August 2017

Gundel Harms

11

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1 August 2017

language of work or name

English

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publication date

27 July 2012

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1 August 2017

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1 August 2017

volume

7

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1 August 2017

issue

7

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1 August 2017

page(s)

e41637

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Creative Commons CC0 License

1 August 2017

copyright license

start time

27 July 2012

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April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407225

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1 reference

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Adherence to combination prophylaxis for prevention of mother-to-child-transmission of HIV in Tanzania

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407225

European mitochondrial DNA haplogroups and metabolic changes during antiretroviral therapy in AIDS Clinical Trials Group Study A5142

6 July 2018

1 reference

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Progressive mitochondrial compromise in brains and livers of primates exposed in utero to nucleoside reverse transcriptase inhibitors (NRTIs)

6 July 2018

1 reference

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Neurodevelopment and in utero antiretroviral exposure of HIV-exposed uninfected infants

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407225

Antiretroviral exposure and lymphocyte mtDNA content among uninfected infants of HIV-1-infected women

6 July 2018

1 reference

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R964C mutation of DNA polymerase gamma imparts increased stavudine toxicity by decreasing nucleoside analog discrimination and impairing polymerase activity

6 July 2018

1 reference

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Mitochondrial DNA haplogroups influence lipoatrophy after highly active antiretroviral therapy

6 July 2018

1 reference

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Mutational analysis of the mitochondrial tRNA genes and flanking regions in umbilical cord tissue from uninfected infants receiving AZT-based therapies for prophylaxis of HIV-1.

6 July 2018

1 reference

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Mechanisms of zidovudine-induced mitochondrial toxicity and myopathy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407225

Increased mtDNA levels without change in mitochondrial enzymes in peripheral blood mononuclear cells of infants born to HIV-infected mothers on antiretroviral therapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407225

Age-dependent mitochondrial DNA 4977bp depletion in human skeletal muscle

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1 reference

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Adenosine 3',5'-cyclic monophosphate (cAMP)-dependent phosphoregulation of mitochondrial complex I is inhibited by nucleoside reverse transcriptase inhibitors

6 July 2018

1 reference

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Impact of nucleoside reverse transcriptase inhibitors on mitochondria in human immunodeficiency virus type 1-infected children receiving highly active antiretroviral therapy

6 July 2018

1 reference

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Mitochondrial AZT metabolism

6 July 2018

1 reference

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Anti-HIV drugs and the mitochondria

6 July 2018

1 reference

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Cell culture models for the investigation of NRTI-induced mitochondrial toxicity. Relevance for the prediction of clinical toxicity

6 July 2018

1 reference

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Mitochondrial DNA and RNA increase in peripheral blood mononuclear cells from HIV-1-infected patients randomized to receive stavudine-containing or stavudine-sparing combination therapy

6 July 2018

1 reference

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Possible ways nucleoside analogues can affect mitochondrial DNA content and gene expression during HIV therapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407225

HIV-1 triggers mitochondrion death.

6 July 2018

1 reference

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HIV-associated mitochondrial toxicity in pregnancy

6 July 2018

1 reference

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Mitochondrial haplogroups and peripheral neuropathy during antiretroviral therapy: an adult AIDS clinical trials group study

6 July 2018

1 reference

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Mitochondrial toxicity in fetal Erythrocebus patas monkeys exposed transplacentally to zidovudine plus lamivudine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407225

Mitochondrial dna depletion, oxidative stress, and mutation: mechanisms of dysfunction from nucleoside reverse transcriptase inhibitors

6 July 2018

1 reference

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Mitochondrial DNA variation in human evolution and disease

6 July 2018

1 reference

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Mutations in mitochondrial DNA accumulate differentially in three different human tissues during ageing

6 July 2018

1 reference

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Role of placental cytokines and inflammation in vertical transmission of HIV infection

6 July 2018

1 reference

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Inflammatory cytokine expression is correlated with the level of human immunodeficiency virus (HIV) transcripts in HIV-infected placental trophoblastic cells

6 July 2018

1 reference

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The study of mitochondrial gene modifications in human placenta.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407225

Mitochondrial myopathy caused by long-term zidovudine therapy

6 July 2018

1 reference

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Effect of anti-human immunodeficiency virus nucleoside analogs on mitochondrial DNA and its implication for delayed toxicity

6 July 2018

1 reference

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Depletion of muscle mitochondrial DNA in AIDS patients with zidovudine-induced myopathy

6 July 2018

1 reference

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Deleterious mitochondrial DNA mutations accumulate in aging human tissues

6 July 2018

1 reference

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1 reference

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Mitochondrial DNA damage is involved in apoptosis caused by pro-inflammatory cytokines in human OA chondrocytes.

6 July 2018

1 reference

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Erythrocebus patas monkey offspring exposed perinatally to NRTIs sustain skeletal muscle mitochondrial compromise at birth and at 1 year of age.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3407225

Transplacentally exposed human and monkey newborn infants show similar evidence of nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity

27 October 2018

1 reference

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Effect of tea catechins on mitochondrial DNA 4977-bp deletions in human leucocytes

27 October 2018

1 reference

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27 October 2018

1 reference

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1 reference

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27 October 2018

1 reference

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27 October 2018

1 reference

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27 October 2018

1 reference

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27 October 2018

1 reference

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27 October 2018

1 reference

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27 October 2018

1 reference

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Differential incorporation and removal of antiviral deoxynucleotides by human DNA polymerase gamma

27 October 2018

1 reference

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Apparent Turnover of Mitochondrial Deoxyribonucleic Acid and Mitochondrial Phospholipids in the Tissues of the Rat

27 October 2018

1 reference

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27 October 2018

1 reference

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27 October 2018

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12 December 2020

Reproducible quantitative PCR of mitochondrial and nuclear DNA copy number using the LightCycler

1 reference

12 December 2020

Quantification of human mitochondrial DNA in a real time PCR

1 reference

12 December 2020

Mitochondrial (mt)DNA changes in tissue may not be reflected by depletion of mtDNA in peripheral blood mononuclear cells in HIV-infected patients

1 reference

12 December 2020

Sensitive detection of the 4977-bp deletion in human mitochondrial DNA of young individuals

1 reference

12 December 2020

Infection with HIV-1 induces a decrease in mtDNA

1 reference

12 December 2020

The mitochondrial pharmacogenomics of haplogroup T: MTND2*LHON4917G and antiretroviral therapy-associated peripheral neuropathy

1 reference

12 December 2020

Long-term mitochondrial toxicity in HIV-uninfected infants born to HIV-infected mothers

1 reference

12 December 2020

Fetal patas monkeys sustain mitochondrial toxicity as a result of in utero zidovudine exposure

1 reference

12 December 2020

Smoking-associated mitochondrial DNA mutations and lipid peroxidation in human lung tissues

1 reference

12 December 2020

Depletion of mitochondrial DNA in HIV-1-infected patients and its amelioration by antiretroviral therapy

1 reference

12 December 2020

Novel mutation of human DNA polymerase gamma associated with mitochondrial toxicity induced by anti-HIV treatment

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12 December 2020

Down modulation of TNF-alpha mRNA placental expression by AZT used for the prevention of HIV-1 mother-to-child transmission

1 reference

12 December 2020

Mitochondrial DNA Levels in Fat and Blood Cells from Patients with Lipodystrophy or Peripheral Neuropathy and the Effect of 90 Days of High-Dose Coenzyme Q Treatment: A Randomized, Double-Blind, Placebo-Controlled Pilot Study

1 reference

12 December 2020

The effect of chronic alcohol consumption on mitochondrial DNA mutagenesis in human blood

1 reference

12 December 2020

Nucleoside exposure in the children of HIV-infected women receiving antiretroviral drugs: absence of clear evidence for mitochondrial disease in children who died before 5 years of age in five United States cohorts

1 reference

12 December 2020

Decrease in cytochrome c oxidase and cytochrome oxidase subunit I messenger RNA levels in preeclamptic pregnancies

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0041637

Identifiers

DOI

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1 August 2017

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1 August 2017

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