Identification of the gene cluster for the dithiolopyrrolone antibiotic holomycin in Streptomyces clavuligerus (Q34359207)

1 August 2017

Identification of the gene cluster for the dithiolopyrrolone antibiotic holomycin in Streptomyces clavuligerus (English)

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Streptomyces clavuligerus

1 August 2017

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Streptomyces coelicolor

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Streptomyces flavovirens

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Streptomyces katsurahamanus

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Streptomyces flavogriseus

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Streptomyces albidoflavus

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Streptomyces jumonjinensis

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N-{4-oxo-5H-[1,2]dithiolo[3,4-b]pyrrol-3-yl}ethanimidic acid

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1 reference

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Bo Li

1

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Christopher T. Walsh

series ordinal

2

object named as

Christopher T Walsh

1 reference

PubMed ID

21041678

1 August 2017

language of work or name

English

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publication date

1 November 2010

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1 August 2017

5

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full work available at URL

inferred from page(s)

https://www.pnas.org/content/pnas/107/46/19731.full.pdf

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1073/pnas.1014140107?email=unpaywall_01@example.com

published in

Proceedings of the National Academy of Sciences of the United States of America

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1 August 2017

107

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1 August 2017

46

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1 August 2017

19731-19735

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https://api.unpaywall.org/v2/10.1073/pnas.1014140107?email=unpaywall_01@example.com

1 August 2017

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19 March 2024

access restriction status

open access

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inferred from online access status

cites work

Dithiolopyrrolone antibiotic formation induced by adding valeric acid to the culture broth of Saccharothrix algeriensis.

1 reference

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Total biosynthesis: in vitro reconstitution of polyketide and nonribosomal peptide pathways.

6 July 2018

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The epipolythiodioxopiperazine (ETP) class of fungal toxins: distribution, mode of action, functions and biosynthesis

6 July 2018

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Biosynthesis and mode of action of lantibiotics.

6 July 2018

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PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin

6 July 2018

1 reference

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Mutants of Streptomyces clavuligerus with disruptions in different genes for clavulanic acid biosynthesis produce large amounts of holomycin: possible cross-regulation of two unrelated secondary metabolic pathways

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993409

New dithiolopyrrolone antibiotics from Saccharothrix sp. SA 233. II. Physicochemical properties and structure elucidation.

6 July 2018

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The clavulanic acid biosynthetic cluster of Streptomyces clavuligerus: genetic organization of the region upstream of the car gene

6 July 2018

1 reference

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Phosphopantothenoylcysteine synthetase from Escherichia coli. Identification and characterization of the last unidentified coenzyme A biosynthetic enzyme in bacteria

6 July 2018

1 reference

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Biosynthesis of complex polyketides in a metabolically engineered strain of E. coli

6 July 2018

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Antimicrobial properties and mode of action of the pyrrothine holomycin

6 July 2018

1 reference

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Thiomarinol, a new hybrid antimicrobial antibiotic produced by a marine bacterium. Fermentation, isolation, structure, and antimicrobial activity.

6 July 2018

1 reference

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Mode of Action of Thiolutin, an Inhibitor of Macromolecular Synthesis in Saccharomyces cerevisiae

6 July 2018

1 reference

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Utilization of ornithine and arginine as specific precursors of clavulanic acid

6 July 2018

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Biologically active metabolites from Xenorhabdus spp., Part 1. Dithiolopyrrolone derivatives with antibiotic activity.

6 July 2018

1 reference

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Holomycin and N-propionylholothin, antibiotics produced by a cephamycin C producer

6 July 2018

1 reference

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Holomycin and an antibiotic(MM 19290) related to tunicamycin, metabolites of Streptomyces clavuligerus

6 July 2018

1 reference

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In vitro study of clavulanic acid in combination with penicillin, amoxycillin, and carbenicillin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993409

Expression of pyrrothine N-acyltransferase activities in Saccharothrix algeriensis NRRL B-24137: new insights into dithiolopyrrolone antibiotic biosynthetic pathway.

6 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1014140107

The biosynthetic genes for clavulanic acid and cephamycin production occur as a 'super-cluster' in three Streptomyces

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21041678

12 December 2020

inferred from PubMed ID database lookup

Thiomarinols D, E, F and G, new hybrid antimicrobial antibiotics produced by a marine bacterium; isolation, structure, and antimicrobial activity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21041678

12 December 2020

inferred from PubMed ID database lookup

[Bactericidal, protozoicidal and fungicidal properties of thiolutin]

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21041678

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.1014140107

1 reference

1 August 2017

0 references

1 reference

1 August 2017

1 reference

PubMed ID

21041678