Phase I trial of hydroxychloroquine with dose-intense temozolomide in patients with advanced solid tumors and melanoma (Q34372972)

1 August 2017

title

Phase I trial of hydroxychloroquine with dose-intense temozolomide in patients with advanced solid tumors and melanoma (English)

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1 August 2017

main subject

phase I clinical trial

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Andrea B Troxel

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Katherine L Nathanson

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object named as

Katherine L Nathanson

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Reshma Rangwala

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Robert Leone

2

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Yunyoung C Chang

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Leslie A Fecher

4

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Lynn M Schuchter

5

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Amy Kramer

6

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Kay-See Tan

7

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Daniel F Heitjan

8

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Glenda Rodgers

9

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Maryann Gallagher

10

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Shengfu Piao

11

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Tracey L Evans

13

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Angela M DeMichele

14

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Peter J O'Dwyer

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Jonathon Kaiser

17

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Laura Pontiggia

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Lisa E Davis

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Ravi K Amaravadi

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1 August 2017

publication date

20 May 2014

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1 August 2017

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volume

10

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issue

8

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1 August 2017

page(s)

1369-1379

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A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme

1 August 2017

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Phase I clinical trial and pharmacodynamic evaluation of combination hydroxychloroquine and doxorubicin treatment in pet dogs treated for spontaneously occurring lymphoma

6 July 2018

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Combined autophagy and HDAC inhibition: a phase I safety, tolerability, pharmacokinetic, and pharmacodynamic analysis of hydroxychloroquine in combination with the HDAC inhibitor vorinostat in patients with advanced solid tumors

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Combined autophagy and proteasome inhibition: a phase 1 trial of hydroxychloroquine and bortezomib in patients with relapsed/refractory myeloma

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6 July 2018

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Extended schedule, escalated dose temozolomide versus dacarbazine in stage IV melanoma: final results of a randomised phase III study (EORTC 18032).

6 July 2018

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6 July 2018

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Measurements of tumor cell autophagy predict invasiveness, resistance to chemotherapy, and survival in melanoma

6 July 2018

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Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis.

6 July 2018

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Targeting autophagy augments in vitro and in vivo antimyeloma activity of DNA-damaging chemotherapy

6 July 2018

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6 July 2018

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Phase II Trial of Temozolomide and Sorafenib in Advanced Melanoma Patients with or without Brain Metastases

6 July 2018

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Dose-dense temozolomide regimen for the treatment of brain metastases from melanoma, breast cancer, or lung cancer not amenable to surgery or radiosurgery: a multicenter phase II study.

6 July 2018

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The history and future of chemotherapy for melanoma

6 July 2018

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Pharmacokinetics of hydroxychloroquine and its clinical implications in chemoprophylaxis against malaria caused by Plasmodium vivax

6 July 2018

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Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma

6 July 2018

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DNA damaging agent-induced autophagy produces a cytoprotective adenosine triphosphate surge in malignant glioma cells

6 July 2018

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Temozolomide in metastatic breast cancer (MBC): a phase II trial of the National Cancer Institute of Canada - Clinical Trials Group (NCIC-CTG).

6 July 2018

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Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

6 July 2018

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6 July 2018

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Temozolomide in non-small-cell lung cancer: preliminary results of a phase II trial in previously treated patients

6 July 2018

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6 July 2018

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New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada

6 July 2018

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6 July 2018

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Induction of autophagy in temozolomide treated malignant gliomas.

21 January 2018

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https://api.crossref.org/works/10.4161%2FAUTO.29118

Statistical properties of the traditional algorithm-based designs for phase I cancer clinical trials.

21 January 2018

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21 January 2018

Identifiers

DOI

10.4161/AUTO.29118

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1 August 2017

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1 August 2017

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