Increased noncanonical splicing of autoantigen transcripts provides the structural basis for expression of untolerized epitopes (Q34373182)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15577853%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

title

Increased noncanonical splicing of autoantigen transcripts provides the structural basis for expression of untolerized epitopes (English)

1 reference

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5 January 2020

1

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5 January 2020

Leif E. Peterson

7

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5 January 2020

author name string

Fan Yang

2

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5 January 2020

David P Huston

3

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5 January 2020

Yan Yan

4

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5 January 2020

Yu Yang

5

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5 January 2020

Zeyu Xiong

6

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5 January 2020

Hong Wang

8

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5 January 2020

Xiao-Feng Yang

9

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5 January 2020

language of work or name

English

0 references

publication date

1 December 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15577853%20AND%20SRC:MED&resulttype=core&format=json

The Journal of Allergy and Clinical Immunology

5 January 2020

published in

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5 January 2020

volume

114

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5 January 2020

page(s)

1463-1470

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5 January 2020

issue

6

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A novel mechanism of alternative promoter and splicing regulates the epitope generation of tumor antigen CML66-L.

5 January 2020

cites work

1 reference

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Advances in B-cell epitope analysis of autoantigens in connective tissue diseases

6 July 2018

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Mechanisms of alternative pre-messenger RNA splicing

6 July 2018

1 reference

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Finding signals that regulate alternative splicing in the post-genomic era

6 July 2018

1 reference

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Signals and their transduction pathways regulating alternative splicing: a new dimension of the human genome

6 July 2018

1 reference

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Distinct sets of adjacent heterogeneous nuclear ribonucleoprotein (hnRNP) A1/A2 binding sites control 5' splice site selection in the hnRNP A1 mRNA precursor

6 July 2018

1 reference

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From T to B and back again: positive feedback in systemic autoimmune disease

6 July 2018

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A genomic view of alternative splicing

6 July 2018

1 reference

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Novel alternative splicings of BPAG1 (bullous pemphigoid antigen 1) including the domain structure closely related to MACF (microtubule actin cross-linking factor)

6 July 2018

1 reference

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Lupus autoantibodies recognize the product of an alternative open reading frame of SmB/B'.

6 July 2018

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Regulation of the immune response by antigen

6 July 2018

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Genome-wide detection of alternative splicing in expressed sequences of human genes

6 July 2018

1 reference

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A listing of human tumor antigens recognized by T cells

6 July 2018

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Differential splicing of the IA-2 mRNA in pancreas and lymphoid organs as a permissive genetic mechanism for autoimmunity against the IA-2 type 1 diabetes autoantigen

6 July 2018

1 reference

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Initial sequencing and analysis of the human genome

6 July 2018

1 reference

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"Promiscuous" expression of tissue antigens in the thymus: a key to T-cell tolerance and autoimmunity?

6 July 2018

1 reference

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Death, autoantigen modifications, and tolerance

6 July 2018

1 reference

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Humoral autoreactivity to an alternatively spliced variant of ICA512/IA-2 in Type I diabetes

6 July 2018

1 reference

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Conditional up-regulation of MHC class I in skeletal muscle leads to self-sustaining autoimmune myositis and myositis-specific autoantibodies

6 July 2018

1 reference

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Characterization of the histone H1-binding protein, NASP, as a cell cycle-regulated somatic protein

6 July 2018

1 reference

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Identification and characterization of a novel Golgi protein, golgin-67.

6 July 2018

1 reference

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Brain and muscle express a unique alternative transcript of alphaII spectrin

6 July 2018

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Cleavage by granzyme B is strongly predictive of autoantigen status: implications for initiation of autoimmunity

6 July 2018

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Identification of both shared and distinct proteins in the major and minor spliceosomes

6 July 2018

1 reference

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Fine specificity of the autoimmune response to the Ro/SSA and La/SSB ribonucleoproteins

6 July 2018

1 reference

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Two COOH-terminal truncated cytoplasmic forms of topoisomerase II alpha in a VP-16-selected lung cancer cell line result from partial gene deletion and alternative splicing

6 July 2018

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Molecular cloning of the RNA polymerase I transcription factor hUBF/NOR-90 (UBTF) gene and localization to 17q21.3 by fluorescence in situ hybridization and radiation hybrid mapping

6 July 2018

1 reference

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A comparison of expressed sequence tags (ESTs) to human genomic sequences

6 July 2018

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Cloning and characterization of islet cell antigen-related protein-tyrosine phosphatase (PTP), a novel receptor-like PTP and autoantigen in insulin-dependent diabetes

6 July 2018

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An alternative splicing product of the lamin A/C gene lacks exon 10.

6 July 2018

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Nuclear proteins of the bovine esophageal epithelium. II. The NuMA gene gives rise to multiple mRNAs and gene products reactive with monoclonal antibody W1

6 July 2018

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One gene, two transcripts: isolation of an alternative transcript encoding for the autoantigen La/SS-B from a cDNA library of a patient with primary Sjögrens' syndrome

6 July 2018

1 reference

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Human 60-kDa SS-A/Ro ribonucleoprotein autoantigen gene (SSA2) localized to 1q31 by fluorescence in situ hybridization

6 July 2018

1 reference

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52-kD SS-A/Ro: genomic structure and identification of an alternatively spliced transcript encoding a novel leucine zipper-minus autoantigen expressed in fetal and adult heart

6 July 2018

1 reference

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Antinuclear antibodies: diagnostic markers for autoimmune diseases and probes for cell biology

6 July 2018

1 reference

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The antigenic index: a novel algorithm for predicting antigenic determinants.

6 July 2018

1 reference

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Evidence for the expression of four myelin basic protein variants in the developing human spinal cord through cDNA cloning

6 July 2018

1 reference

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KU 70/80 lupus autoantigen is the transcription factor induced by interleukins (IL)-13 and -4 leading to induction of 15-lipoxygenase (15-LO) in human cells.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902068

Interferon-alpha, but not the ABL-kinase inhibitor imatinib (STI571), induces expression of myeloblastin and a specific T-cell response in chronic myeloid leukemia

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902068

EST comparison indicates 38% of human mRNAs contain possible alternative splice forms.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902068

Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells.

27 October 2018

1 reference

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Human thyroperoxidase in its alternatively spliced form (TPO2) is enzymatically inactive and exhibits changes in intracellular processing and trafficking

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15577853

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.JACI.2004.09.006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15577853%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15577853%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

1 reference