Induction of FPN1 transcription by MTF-1 reveals a role for ferroportin in transition metal efflux (Q34374111)

1 August 2017

Induction of FPN1 transcription by MTF-1 reveals a role for ferroportin in transition metal efflux (English)

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1 August 2017

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Marie-Berengere Troadec

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1 August 2017

Diane McVey Ward

2

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1 August 2017

Eric Lo

3

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1 August 2017

Jerry Kaplan

4

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1 August 2017

Ivana De Domenico

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1 August 2017

language of work or name

English

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publication date

5 August 2010

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1 August 2017

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116

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4657-4664

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22

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describes a project that uses

1 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2996121/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Heme controls ferroportin1 (FPN1) transcription involving Bach1, Nrf2 and a MARE/ARE sequence motif at position -7007 of the FPN1 promoter

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Cadmium increases ferroportin-1 gene expression in J774 macrophage cells via the production of reactive oxygen species

6 July 2018

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Effects of various metal ions on the gene expression of iron exporter ferroportin-1 in J774 macrophages

6 July 2018

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Ferroportin is a manganese-responsive protein that decreases manganese cytotoxicity and accumulation

6 July 2018

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Regulation of hepcidin and iron-overload disease

6 July 2018

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Hepcidin-induced internalization of ferroportin requires binding and cooperative interaction with Jak2.

6 July 2018

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Iron loading increases ferroportin heterogeneous nuclear RNA and mRNA levels in murine J774 macrophages

6 July 2018

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Iron homeostasis and erythropoiesis

6 July 2018

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Sequential regulation of ferroportin expression after erythrophagocytosis in murine macrophages: early mRNA induction by haem, followed by iron-dependent protein expression

6 July 2018

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Understanding the mechanisms of zinc-sensing by metal-response element binding transcription factor-1 (MTF-1).

6 July 2018

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Efficacy of zinc treatment against iron-induced toxicity in rat hepatoma cell line H4-II-E-C3.

6 July 2018

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Zip14 (Slc39a14) mediates non-transferrin-bound iron uptake into cells

6 July 2018

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Effect of Zn treatment on wild type and MT-null cell lines in relation to apoptotic and/or necrotic processes and on MT isoform gene expression

6 July 2018

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Iron imports. III. Transfer of iron from the mucosa into circulation

6 July 2018

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Presence of the iron exporter ferroportin at the plasma membrane of macrophages is enhanced by iron loading and down-regulated by hepcidin

6 July 2018

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The molecular basis of ferroportin-linked hemochromatosis

6 July 2018

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Interleukin-6 regulates the zinc transporter Zip14 in liver and contributes to the hypozincemia of the acute-phase response

6 July 2018

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Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

6 July 2018

1 reference

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Loss of metal transcription factor-1 suppresses tumor growth through enhanced matrix deposition

6 July 2018

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Protection against zinc toxicity by metallothionein and zinc transporter 1

6 July 2018

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Activity of metal-responsive transcription factor 1 by toxic heavy metals and H2O2 in vitro is modulated by metallothionein

6 July 2018

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Knockout of 'metal-responsive transcription factor' MTF-1 in Drosophila by homologous recombination reveals its central role in heavy metal homeostasis

6 July 2018

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Inhibitors of histone deacetylase and DNA methyltransferase synergistically activate the methylated metallothionein I promoter by activating the transcription factor MTF-1 and forming an open chromatin structure

6 July 2018

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Iron increases expression of iron-export protein MTP1 in lung cells

6 July 2018

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Combinatorial control of yeast FET4 gene expression by iron, zinc, and oxygen.

6 July 2018

1 reference

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Placenta growth factor gene expression is induced by hypoxia in fibroblasts: a central role for metal transcription factor-1.

6 July 2018

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A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation

6 July 2018

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A novel mammalian iron-regulated protein involved in intracellular iron metabolism

6 July 2018

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Zinc and cadmium can promote rapid nuclear translocation of metal response element-binding transcription factor-1

6 July 2018

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Yeast SMF1 mediates H(+)-coupled iron uptake with concomitant uncoupled cation currents

6 July 2018

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Cloning and characterization of a mammalian proton-coupled metal-ion transporter

6 July 2018

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Zinc absorption in women during pregnancy and lactation: a longitudinal study

6 July 2018

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Regulation of metallothionein genes by heavy metals appears to be mediated by a zinc-sensitive inhibitor that interacts with a constitutively active transcription factor, MTF-1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996121

The transcription factor MTF-1 is essential for basal and heavy metal-induced metallothionein gene expression

6 July 2018

1 reference

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A 12-base-pair DNA motif that is repeated several times in metallothionein gene promoters confers metal regulation to a heterologous gene

6 July 2018

1 reference

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Identification of multiple metal regulatory elements in mouse metallothionein-I promoter by assaying synthetic sequences.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996121

Studies of marginal zinc deprivation in rhesus monkeys. III. Use of liver biopsy in the assessment of zinc status

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996121

The physiological role of zinc as an antioxidant

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996121

The ferroportin metal efflux proteins function in iron and cobalt homeostasis in Arabidopsis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996121

Zinc supplementation reduces iron absorption through age-dependent changes in small intestine iron transporter expression in suckling rat pups.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996121

Expression of the duodenal iron transporters divalent-metal transporter 1 and ferroportin 1 in iron deficiency and iron overload

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996121

The IRT1 protein from Arabidopsis thaliana is a metal transporter with a broad substrate range.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996121

Effect of Excess Dietary Zinc on Tissue Storage of Iron in Rats

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20688958

12 December 2020

inferred from PubMed ID database lookup

Zinc deficiency causes oxidative damage to proteins, lipids and DNA in rat testes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20688958

12 December 2020

inferred from PubMed ID database lookup

Zinc deficiency in pregnant Long-Evans hooded rats: teratogenicity and tissue trace elements

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20688958

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1182/BLOOD-2010-04-278614

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1 August 2017

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1 August 2017

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