5-azacytidine reduces methylation, promotes differentiation and induces tumor regression in a patient-derived IDH1 mutant glioma xenograft. (Q34374136)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24077805%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

title

5-azacytidine reduces methylation, promotes differentiation and induces tumor regression in a patient-derived IDH1 mutant glioma xenograft (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24077805%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

1 reference

3

1 reference

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23 February 2020

6

Charles G Eberhart

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24077805%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

7

Jon D Weingart

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24077805%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

9

Stephen B Baylin

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24077805%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

author name string

Alexandra Borodovsky

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24077805%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Vafi Salmasi

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24077805%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Armida W M Fabius

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24077805%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Gilson S Baia

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24077805%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Gary L Gallia

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24077805%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Timothy A Chan

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24077805%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Gregory J Riggins

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24077805%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

language of work or name

English

0 references

publication date

1 October 2013

1 reference

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23 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24077805%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

volume

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24077805%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

page(s)

1737-1747

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24077805%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24077805%20AND%20SRC:MED&resulttype=core&format=json

Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT Inhibitor Decitabine.

23 February 2020

cites work

1 reference

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6 July 2018

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BMP4, a strong better prognosis predictor, has a subtype preference and cell development association in gliomas

6 July 2018

1 reference

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Disruption of wild-type IDH1 suppresses D-2-hydroxyglutarate production in IDH1-mutated gliomas.

6 July 2018

1 reference

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Identification of retinol binding protein 1 promoter hypermethylation in isocitrate dehydrogenase 1 and 2 mutant gliomas.

6 July 2018

1 reference

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A heterozygous IDH1R132H/WT mutation induces genome-wide alterations in DNA methylation.

6 July 2018

1 reference

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Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas

6 July 2018

1 reference

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Transient low doses of DNA-demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells

6 July 2018

1 reference

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A DNA hypermethylation module for the stem/progenitor cell signature of cancer.

6 July 2018

1 reference

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IDH mutation impairs histone demethylation and results in a block to cell differentiation

6 July 2018

1 reference

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IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype

6 July 2018

1 reference

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Frequent mutation of isocitrate dehydrogenase (IDH)1 and IDH2 in cholangiocarcinoma identified through broad-based tumor genotyping

6 July 2018

1 reference

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An in vivo patient-derived model of endogenous IDH1-mutant glioma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3858560

IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3858560

Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3858560

DNA methylation, isocitrate dehydrogenase mutation, and survival in glioma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3858560

Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3858560

Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3858560

Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3858560

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3858560

Recurring mutations found by sequencing an acute myeloid leukemia genome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3858560

CpG island methylation of TMS1/ASC and CASP8 genes in cervical cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3858560

IDH1 and IDH2 mutations in gliomas

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3858560

An integrated genomic analysis of human glioblastoma multiforme

6 July 2018

1 reference

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A novel small molecule that selectively inhibits glioblastoma cells expressing EGFRvIII.

6 July 2018

1 reference

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5-Aza-cytidine is a potent inhibitor of DNA methyltransferase 3a and induces apoptosis in HCT-116 colon cancer cells via Gadd45- and p53-dependent mechanisms

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3858560

Aberrant methylation and down-regulation of TMS1/ASC in human glioblastoma

6 July 2018

1 reference

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Contrasting in vivo and in vitro fates of glioblastoma cell subpopulations with amplified EGFR

6 July 2018

1 reference

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Biological effects of 5-azacytidine in eukaryotes

6 July 2018

1 reference

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Aberrant expression of SOX9 is associated with gastrokine 1 inactivation in gastric cancers

6 July 2018

1 reference

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IDH mutation status in prostate cancer.

27 October 2018

1 reference

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Bone morphogenetic protein 4 induces differentiation of colorectal cancer stem cells and increases their response to chemotherapy in mice.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3858560

Recurrent IDH mutations in high-risk myelodysplastic syndrome or acute myeloid leukemia with isolated del(5q).

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3858560

Genetic subgroups of anaplastic astrocytomas correlate with patient age and survival

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3858560

Plasma and cerebrospinal fluid pharmacokinetics of 5-Aza-2'-deoxycytidine in rabbits and dogs

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24077805

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.18632/ONCOTARGET.1408

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24077805%20AND%20SRC:MED&resulttype=core&format=json

release_eidwiep4jvexzlpwhmxjb6yn2m

23 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/eidwiep4jvexzlpwhmxjb6yn2m

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24077805%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24077805%20AND%20SRC:MED&resulttype=core&format=json