RNA polymerase mutants found through adaptive evolution reprogram Escherichia coli for optimal growth in minimal media (Q34377515)

1 August 2017

title

RNA polymerase mutants found through adaptive evolution reprogram Escherichia coli for optimal growth in minimal media (English)

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1 August 2017

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6

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1 August 2017

8

Bernhard Ø Palsson

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1 August 2017

Tom M Conrad

1

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1 August 2017

Michael Frazier

2

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1 August 2017

Andrew R Joyce

3

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1 August 2017

Byung-Kwan Cho

4

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1 August 2017

Eric M Knight

5

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1 August 2017

Robert Landick

7

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1 August 2017

language of work or name

English

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publication date

5 November 2010

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Proceedings of the National Academy of Sciences of the United States of America

1 August 2017

published in

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1 August 2017

volume

107

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1 August 2017

issue

47

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1 August 2017

page(s)

20500-20505

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Regulatory and metabolic rewiring during laboratory evolution of ethanol tolerance in E. coli.

1 August 2017

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6 July 2018

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Whole-genome resequencing of Escherichia coli K-12 MG1655 undergoing short-term laboratory evolution in lactate minimal media reveals flexible selection of adaptive mutations

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Impact of individual mutations on increased fitness in adaptively evolved strains of Escherichia coli

6 July 2018

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The global, ppGpp-mediated stringent response to amino acid starvation in Escherichia coli

6 July 2018

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Transcription profiling of the stringent response in Escherichia coli

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Evolution of global regulatory networks during a long-term experiment with Escherichia coli

6 July 2018

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Direct versus limited-step reconstitution reveals key features of an RNA hairpin-stabilized paused transcription complex

6 July 2018

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6 July 2018

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Structural perspective on mutations affecting the function of multisubunit RNA polymerases

6 July 2018

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Mouse intestine selects nonmotile flhDC mutants of Escherichia coli MG1655 with increased colonizing ability and better utilization of carbon sources

6 July 2018

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Parallel adaptive evolution cultures of Escherichia coli lead to convergent growth phenotypes with different gene expression states

6 July 2018

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ppGpp: a global regulator in Escherichia coli.

6 July 2018

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6 July 2018

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Statistical significance for genomewide studies

6 July 2018

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Parallel changes in gene expression after 20,000 generations of evolution in Escherichiacoli

6 July 2018

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6 July 2018

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6 July 2018

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The rpoB mutants destabilizing initiation complexes at stringently controlled promoters behave like "stringent" RNA polymerases in Escherichia coli

6 July 2018

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6 July 2018

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The Escherichia coli K-12 "wild types" W3110 and MG1655 have an rph frameshift mutation that leads to pyrimidine starvation due to low pyrE expression levels

6 July 2018

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Effects of the antiterminator BoxA on transcription elongation kinetics and ppGpp inhibition of transcription elongation in Escherichia coli

6 July 2018

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High concentrations of ppGpp decrease the RNA chain growth rate. Implications for protein synthesis and translational fidelity during amino acid starvation in Escherichia coli.

6 July 2018

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A direct effect of guanosine tetraphosphate on pausing of Escherichia coli RNA polymerase during RNA chain elongation.

6 July 2018

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Mapping and sequencing of mutations in the Escherichia colirpoB gene that lead to rifampicin resistance

6 July 2018

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6 July 2018

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6 July 2018

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RpoB8, a rifampicin-resistant termination-proficient RNA polymerase, has an increased Km for purine nucleotides during transcription elongation

6 July 2018

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Isolation of RNA polymerase suppressors of a (p)ppGpp deficiency

6 July 2018

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Comparative genome sequencing of Escherichia coli allows observation of bacterial evolution on a laboratory timescale

21 January 2018

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Ubiquitous transcriptional pausing is independent of RNA polymerase backtracking.

21 January 2018

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21 January 2018

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Gene replacement without selection: regulated suppression of amber mutations in Escherichia coli

21 January 2018

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Mutations of the beta subunit of RNA polymerase alter both transcription pausing and transcription termination in the trp operon leader region in vitro

27 October 2018

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DksA: a critical component of the transcription initiation machinery that potentiates the regulation of rRNA promoters by ppGpp and the initiating NTP

27 October 2018

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12 December 2020

The downstream DNA jaw of bacterial RNA polymerase facilitates both transcriptional initiation and pausing

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12 December 2020

Co-overexpression of Escherichia coli RNA polymerase subunits allows isolation and analysis of mutant enzymes lacking lineage-specific sequence insertions

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12 December 2020

Residual guanosine 3',5'-bispyrophosphate synthetic activity of relA null mutants can be eliminated by spoT null mutations

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12 December 2020

A central role of the RNA polymerase trigger loop in active-site rearrangement during transcriptional pausing

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0911253107

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1 August 2017

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1 August 2017

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