Influence of hepatic impairment on pharmacokinetics of the human GLP-1 analogue, liraglutide. (Q34381400)

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18 January 2020

title

Influence of hepatic impairment on pharmacokinetics of the human GLP-1 analogue, liraglutide (English)

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18 January 2020

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18 January 2020

author name string

Anne Flint

1

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18 January 2020

Khalil Nazzal

2

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18 January 2020

Charlotte Hindsberger

4

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18 January 2020

Milan Zdravkovic

5

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18 January 2020

language of work or name

English

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publication date

1 December 2010

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British Journal of Clinical Pharmacology

18 January 2020

published in

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18 January 2020

volume

70

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18 January 2020

issue

6

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18 January 2020

page(s)

807-814

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Effect of renal impairment on the pharmacokinetics of the GLP-1 analogue liraglutide

18 January 2020

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Glucagon-like peptide-1 as a treatment option for type 2 diabetes and its role in restoring beta-cell mass

6 July 2018

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Effects of liraglutide (NN2211), a long-acting GLP-1 analogue, on glycaemic control and bodyweight in subjects with Type 2 diabetes

6 July 2018

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One week's treatment with the long-acting glucagon-like peptide 1 derivative liraglutide (NN2211) markedly improves 24-h glycemia and alpha- and beta-cell function and reduces endogenous glucose release in patients with type 2 diabetes.

6 July 2018

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GLP-1 derivative liraglutide in rats with beta-cell deficiencies: influence of metabolic state on beta-cell mass dynamics

6 July 2018

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The long-acting GLP-1 derivative NN2211 ameliorates glycemia and increases beta-cell mass in diabetic mice

6 July 2018

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The pharmacokinetics, pharmacodynamics, safety and tolerability of NN2211, a new long-acting GLP-1 derivative, in healthy men.

6 July 2018

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Amylase, Hepatic Enzymes and Bilirubin in Serum of Chronic Alcoholics

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Metabolism and excretion of the once-daily human glucagon-like peptide-1 analog liraglutide in healthy male subjects and its in vitro degradation by dipeptidyl peptidase IV and neutral endopeptidase

6 July 2018

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Effects of the long-acting human glucagon-like peptide-1 analog liraglutide on beta-cell function in normal living conditions.

27 October 2018

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Liraglutide, a long-acting human glucagon-like peptide-1 analog, given as monotherapy significantly improves glycemic control and lowers body weight without risk of hypoglycemia in patients with type 2 diabetes

27 October 2018

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Five weeks of treatment with the GLP-1 analogue liraglutide improves glycaemic control and lowers body weight in subjects with type 2 diabetes

27 October 2018

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The long-acting glucagon-like peptide-1 analogue, liraglutide, inhibits beta-cell apoptosis in vitro

27 October 2018

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The effect of liraglutide, a long-acting glucagon-like peptide 1 derivative, on glycemic control, body composition, and 24-h energy expenditure in patients with type 2 diabetes

27 October 2018

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Improved glycemic control with no weight increase in patients with type 2 diabetes after once-daily treatment with the long-acting glucagon-like peptide 1 analog liraglutide (NN2211): a 12-week, double-blind, randomized, controlled trial

27 October 2018

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The GLP-1 derivative NN2211 restores beta-cell sensitivity to glucose in type 2 diabetic patients after a single dose

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Bedtime administration of NN2211, a long-acting GLP-1 derivative, substantially reduces fasting and postprandial glycemia in type 2 diabetes

27 October 2018

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12 December 2020

Effect of Three Different Injection Sites on the Pharmacokinetics of the Once-Daily Human GLP-1 Analogue Liraglutide

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12 December 2020

Both Subcutaneously and Intravenously Administered Glucagon-Like Peptide I Are Rapidly Degraded From the NH2-Terminus in Type II Diabetic Patients and in Healthy Subjects

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12 December 2020

Glucagon-like peptide-1 reduces hepatic glucose production indirectly through insulin and glucagon in humans

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12 December 2020

10.1111/J.1365-2125.2010.03762.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21175436%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21175436%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PubMed publication ID

21175436

1 reference