Lactisole interacts with the transmembrane domains of human T1R3 to inhibit sweet taste. (Q34387670)

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7 January 2020

title

Lactisole interacts with the transmembrane domains of human T1R3 to inhibit sweet taste (English)

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7 January 2020

main subject

transmembrane protein

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author

Robert Margolskee

8

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7 January 2020

author name string

Peihua Jiang

1

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7 January 2020

Meng Cui

2

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7 January 2020

Baohua Zhao

3

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7 January 2020

Zhan Liu

4

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7 January 2020

Lenore A Snyder

5

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7 January 2020

Lumie M J Benard

6

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7 January 2020

Roman Osman

7

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7 January 2020

Marianna Max

9

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7 January 2020

language of work or name

English

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publication date

24 January 2005

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Journal of Biological Chemistry

7 January 2020

published in

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7 January 2020

volume

280

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issue

15

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7 January 2020

page(s)

15238-15246

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Receptors and transduction in taste

7 January 2020

cites work

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Human receptors for sweet and umami taste

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Mammalian sweet taste receptors

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The receptors for mammalian sweet and umami taste

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Detection of sweet and umami taste in the absence of taste receptor T1r3.

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Putative mammalian taste receptors: a class of taste-specific GPCRs with distinct topographic selectivity

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Positional cloning of the mouse saccharin preference (Sac) locus

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Tas1r3, encoding a new candidate taste receptor, is allelic to the sweet responsiveness locus Sac.

21 January 2018

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Molecular genetic identification of a candidate receptor gene for sweet taste

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The heptahelical domain of GABA(B2) is activated directly by CGP7930, a positive allosteric modulator of the GABA(B) receptor

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Modeling and Mutagenesis of the Binding Site of Calhex 231, a Novel Negative Allosteric Modulator of the Extracellular Ca2+-sensing Receptor

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Positive and negative allosteric modulators of the Ca2+-sensing receptor interact within overlapping but not identical binding sites in the transmembrane domain

21 January 2018

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The cysteine-rich region of T1R3 determines responses to intensely sweet proteins

21 January 2018

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Different functional roles of T1R subunits in the heteromeric taste receptors

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Selective Inhibition of Sweetness by the Sodium Salt of +/-2-(4-Methoxyphenoxy)propanoic Acid

21 January 2018

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21 January 2018

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The serotonin binding site of human and murine 5-HT2B receptors: molecular modeling and site-directed mutagenesis

21 January 2018

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Random mutagenesis of the M3 muscarinic acetylcholine receptor expressed in yeast. Identification of point mutations that "silence" a constitutively active mutant M3 receptor and greatly impair receptor/G protein coupling

21 January 2018

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Conformational changes that occur during M3 muscarinic acetylcholine receptor activation probed by the use of an in situ disulfide cross-linking strategy

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M414287200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15668251%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference