Long-term retinal PEDF overexpression prevents neovascularization in a murine adult model of retinopathy (Q34387956)

1 August 2017

Long-term retinal PEDF overexpression prevents neovascularization in a murine adult model of retinopathy (English)

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1 August 2017

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7

Fatima Bosch

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1 August 2017

Virginia Haurigot

1

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1 August 2017

Pilar Villacampa

2

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1 August 2017

Albert Ribera

3

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1 August 2017

Assumpcio Bosch

4

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1 August 2017

David Ramos

5

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1 August 2017

Jesus Ruberte

6

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1 August 2017

language of work or name

English

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publication date

20 July 2012

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1 August 2017

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1 August 2017

7

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7

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1 August 2017

e41511

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Creative Commons Attribution 4.0 International

1 August 2017

start time

20 July 2012

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Targeting cancer vasculature via endoglin/CD105: a novel antibody-based diagnostic and therapeutic strategy in solid tumours

6 July 2018

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The significance of neuronal and glial cell changes in the rat retina during oxygen-induced retinopathy

6 July 2018

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Molecular signatures of disease brain endothelia provide new sites for CNS-directed enzyme therapy

6 July 2018

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Increased intraocular insulin-like growth factor-I triggers blood-retinal barrier breakdown

6 July 2018

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Differential expression of anti-angiogenic factors and guidance genes in the developing macula

6 July 2018

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Detection of intact rAAV particles up to 6 years after successful gene transfer in the retina of dogs and primates

6 July 2018

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Endogenous VEGF is required for visual function: evidence for a survival role on müller cells and photoreceptors

6 July 2018

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Treatment of leber congenital amaurosis due to RPE65 mutations by ocular subretinal injection of adeno-associated virus gene vector: short-term results of a phase I trial

6 July 2018

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The angio-fibrotic switch of VEGF and CTGF in proliferative diabetic retinopathy

6 July 2018

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Effect of gene therapy on visual function in Leber's congenital amaurosis

6 July 2018

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Safety and efficacy of gene transfer for Leber's congenital amaurosis

6 July 2018

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Novel AAV serotypes for improved ocular gene transfer

6 July 2018

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The 37/67-kilodalton laminin receptor is a receptor for adeno-associated virus serotypes 8, 2, 3, and 9

6 July 2018

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PEDF induces apoptosis in human endothelial cells by activating p38 MAP kinase dependent cleavage of multiple caspases

6 July 2018

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Pigment epithelium-derived factor downregulates vascular endothelial growth factor (VEGF) expression and inhibits VEGF-VEGF receptor 2 binding in diabetic retinopathy

6 July 2018

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Salutary effect of pigment epithelium-derived factor in diabetic nephropathy: evidence for antifibrogenic activities

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401102

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401102

Pigment epithelium-derived factor (PEDF) is an endogenous antiinflammatory factor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401102

Retinal angiogenesis in development and disease

6 July 2018

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Pigment epithelium-derived factor inhibits angiogenesis via regulated intracellular proteolysis of vascular endothelial growth factor receptor 1

6 July 2018

1 reference

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Neuroprotective and antiangiogenic actions of PEDF in the eye: molecular targets and therapeutic potential.

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401102

Increased ocular levels of IGF-1 in transgenic mice lead to diabetes-like eye disease.

6 July 2018

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Recombinant adeno-associated virus serotype 4 mediates unique and exclusive long-term transduction of retinal pigmented epithelium in rat, dog, and nonhuman primate after subretinal delivery

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401102

Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401102

Adeno-associated virus type-2 expression of pigmented epithelium-derived factor or Kringles 1-3 of angiostatin reduce retinal neovascularization

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401102

AAV-mediated gene transfer of pigment epithelium-derived factor inhibits choroidal neovascularization

6 July 2018

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Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium-derived factor

6 July 2018

1 reference

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In vivo protection of photoreceptors from light damage by pigment epithelium-derived factor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401102

HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401102

Matrix metalloproteinases and their natural inhibitors in fibrovascular membranes of proliferative diabetic retinopathy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401102

Pigment epithelium-derived factor: a potent inhibitor of angiogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401102

Structural and comparative analysis of the mouse gene for pigment epithelium-derived factor (PEDF).

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401102

Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401102

Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401102

Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularization

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401102

Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401102

Neuronal differentiation of retinoblastoma cells induced by medium conditioned by human RPE cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401102

Novel mechanism for age-related macular degeneration: an equilibrium shift between the angiogenesis factors VEGF and PEDF.

6 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0041511

Real-time, noninvasive in vivo assessment of adeno-associated virus-mediated retinal transduction

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3401102

Pigment epithelium-derived factor delays the death of photoreceptors in mouse models of inherited retinal degenerations

27 October 2018

1 reference

12 December 2020

Vascular endothelial growth factor induces expression of connective tissue growth factor via KDR, Flt1, and phosphatidylinositol 3-kinase-akt-dependent pathways in retinal vascular cells

1 reference

12 December 2020

Vitreous levels of insulin-like growth factor-I in patients with proliferative diabetic retinopathy

1 reference

12 December 2020

Unbalanced vitreous levels of pigment epithelium-derived factor and vascular endothelial growth factor in diabetic retinopathy

1 reference

12 December 2020

Insulin-like growth factors in vitreous. Studies in control and diabetic subjects with neovascularization

1 reference

12 December 2020

Oxygen-induced retinopathy in the mouse

1 reference

12 December 2020

1 reference

12 December 2020

Vascular endothelial growth factor upregulates the expression of matrix metalloproteinases in vascular smooth muscle cells: role of flt-1

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0041511

Identifiers

DOI

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1 August 2017

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1 August 2017

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