The major human abasic endonuclease: formation, consequences and repair of abasic lesions in DNA. (Q34390593)

1 August 2017

1 reference

title

The major human abasic endonuclease: formation, consequences and repair of abasic lesions in DNA. (English)

1 reference

1 August 2017

Wilson DM 3rd

1

1 reference

PubMed ID

11585362

1 August 2017

Barsky D

series ordinal

2

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PubMed ID

11585362

1 August 2017

language of work or name

English

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publication date

1 May 2001

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1 August 2017

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1 August 2017

485

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1 August 2017

4

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1 August 2017

283-307

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Studies on depurination of DNA by heat

1 August 2017

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7 January 2021

Rate of depurination of native deoxyribonucleic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Heat-induced depyrimidination of deoxyribonucleic acid in neutral solution

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Mutagenesis by apurinic/apyrimidinic sites

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Instability and decay of the primary structure of DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

DNA glycosylases in the base excision repair of DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Initiation of base excision repair: glycosylase mechanisms and structures

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

A method for detecting abasic sites in living cells: age-dependent changes in base excision repair

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Role of exonuclease III in the base excision repair of uracil-containing DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Depurination causes mutations in SOS-induced cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

The response of eukaryotic topoisomerases to DNA damage

1 reference

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7 January 2021

Effects of uracil incorporation, DNA mismatches, and abasic sites on cleavage and religation activities of mammalian topoisomerase I.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Depurination decreases fidelity of DNA synthesis in vitro

1 reference

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7 January 2021

Coding properties of poly(deoxycytidylic acid) templates containing uracil or apyrimidinic sites: in vitro modulation of mutagenesis by deoxyribonucleic acid repair enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Insertion of nucleotides opposite apurinic/apyrimidinic sites in deoxyribonucleic acid during in vitro synthesis: uniqueness of adenine nucleotides

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Depurination-induced infidelity of deoxyribonucleic acid synthesis with purified deoxyribonucleic acid replication proteins in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Infidelity of DNA synthesis associated with bypass of apurinic sites

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Mutational specificity of depurination

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Mutation frequency and spectrum resulting from a single abasic site in a single-stranded vector

1 reference

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7 January 2021

Effects of abasic sites and DNA single-strand breaks on prokaryotic RNA polymerases

1 reference

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7 January 2021

On the mechanism of preferential incorporation of dAMP at abasic sites in translesional DNA synthesis. Role of proofreading activity of DNA polymerase and thermodynamic characterization of model template-primers containing an abasic site

1 reference

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7 January 2021

Mechanism of bypass synthesis through an abasic site analog by DNA polymerase I

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Translesional synthesis on DNA templates containing a single abasic site. A mechanistic study of the "A rule".

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Abasic sites induce triplet-repeat expansion during DNA replication in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

SOS and Mayday: multiple inducible mutagenic pathways in Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Specificity of mutagenesis resulting from the induction of the SOS system in the absence of mutagenic treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Roles of E. coli DNA polymerases IV and V in lesion-targeted and untargeted SOS mutagenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Specificity of the mutator caused by deletion of the yeast structural gene (APN1) for the major apurinic endonuclease

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Novel mutagenic properties of abasic sites in Saccharomyces cerevisiae.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Lesions in DNA: hurdles for polymerases

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Mutagenic properties of a unique abasic site in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Mutagenicity of a unique apurinic/apyrimidinic site in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Coding properties of a unique apurinic/apyrimidinic site replicated in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Mechanism of mutation on DNA templates containing synthetic abasic sites: study with a double strand vector

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Mutagenesis by apurinic sites in normal and ataxia telangiectasia human lymphoblastoid cells

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Mechanisms of accurate translesion synthesis by human DNA polymerase eta

1 reference

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7 January 2021

The human DINB1 gene encodes the DNA polymerase Poltheta

1 reference

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7 January 2021

Error-prone lesion bypass by human DNA polymerase eta.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Error-free and error-prone lesion bypass by human DNA polymerase kappa in vitro

1 reference

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7 January 2021

Inefficient bypass of an abasic site by DNA polymerase eta.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Proliferating cell nuclear antigen promotes DNA synthesis past template lesions by mammalian DNA polymerase delta

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

The human REV1 gene codes for a DNA template-dependent dCMP transferase

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Eukaryotic polymerases iota and zeta act sequentially to bypass DNA lesions

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

An abasic site in DNA. Solution conformation determined by proton NMR and molecular mechanics calculations.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

NMR studies of abasic sites in DNA duplexes: deoxyadenosine stacks into the helix opposite acyclic lesions

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Refined solution structure of a DNA heteroduplex containing an aldehydic abasic site

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Solution conformation of an abasic DNA undecamer duplex d(CGCACXCACGC) x d(GCGTGTGTGCG): the unpaired thymine stacks inside the helix

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

NMR studies of abasic sites in DNA duplexes: deoxyadenosine stacks into the helix opposite the cyclic analogue of 2-deoxyribose

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

The abasic site as a challenge to DNA polymerase. A nuclear magnetic resonance study of G, C and T opposite a model abasic site

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

High-field NMR and restrained molecular modeling studies on a DNA heteroduplex containing a modified apurinic abasic site in the form of covalently linked 9-aminoellipticine

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Solution structure of a duplex DNA with an abasic site in a dA tract

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

2-Aminopurine fluorescence studies of base stacking interactions at abasic sites in DNA: metal-ion and base sequence effects

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Experimental and theoretical studies of the conformational perturbations induced by an abasic site

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

The impact of abasic sites on DNA flexibility

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Abasic sites in duplex DNA: molecular modeling of sequence-dependent effects on conformation

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

New insights into the structure of abasic DNA from molecular dynamics simulations

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

2'-deoxyribonolactone lesion in DNA: refined solution structure determined by nuclear magnetic resonance and molecular modeling

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Influence of abasic and anucleosidic sites on the stability, conformation, and melting behavior of a DNA duplex: correlations of thermodynamic and structural data

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Thermodynamic consequences of an abasic lesion in duplex DNA are strongly dependent on base sequence

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Base-base mismatches. Thermodynamics of double helix formation for dCA3XA3G + dCT3YT3G (X, Y = A,C,G,T).

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Sequence-dependent repair of synthetic AP sites in 15-mer and 35-mer oligonucleotides: role of thermodynamic stability imposed by neighbor bases

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

A specific partner for abasic damage in DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Interaction and solvation energies of nonpolar DNA base analogues and their role in polymerase insertion fidelity

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Endonuclease IV of Escherichia coli is induced by paraquat

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: definition of a family of DNA repair enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Isolation of cDNA clones encoding a human apurini/apyrimidinic endonuclease that corects DNA repair and mutagenisis defects inE.coli xth(exonuclease III) mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

cDNA cloning, sequencing, expression and possible domain structure of human APEX nuclease homologous to Escherichia coli exonuclease III

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Two distinct human DNA diesterases that hydrolyze 3′-blocking deoxyribose fragments from oxidized DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Yeast structural gene (APN1) for the major apurinic endonuclease: homology to Escherichia coli endonuclease IV

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Identification of APN2, the Saccharomyces cerevisiae homolog of the major human AP endonuclease HAP1, and its role in the repair of abasic sites

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

The Saccharomyces cerevisiae ETH1 gene, an inducible homolog of exonuclease III that provides resistance to DNA-damaging agents and limits spontaneous mutagenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Apurinic endonuclease activity of yeast Apn2 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Regulation of eukaryotic abasic endonucleases and their role in genetic stability

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Repair of oxidative damage to DNA: enzymology and biology

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Removal of 3'-phosphoglycolate from DNA strand-break damage in an oligonucleotide substrate by recombinant human apurinic/apyrimidinic endonuclease 1

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

3'-phosphodiesterase activity of human apurinic/apyrimidinic endonuclease at DNA double-strand break ends

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Base excision repair of oxidative DNA damage activated by XPG protein

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicals

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

A novel action of human apurinic/apyrimidinic endonuclease: excision of L-configuration deoxyribonucleoside analogs from the 3' termini of DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Second human protein with homology to the Escherichia coli abasic endonuclease exonuclease III

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Purification and amino-terminal amino acid sequence of an apurinic/apyrimidinic endonuclease from calf thymus

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Isolation of cDNA clones encoding an enzyme from bovine cells that repairs oxidative DNA damagein vitro: homology with bacterial repair enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Domain mapping of human apurinic/apyrimidinic endonuclease. Structural and functional evidence for a disordered amino terminus and a tight globular carboxyl domain.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]

1 reference

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7 January 2021

Two divalent metal ions in the active site of a new crystal form of human apurinic/apyrimidinic endonuclease, Ape1: implications for the catalytic mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Structure and function of the multifunctional DNA-repair enzyme exonuclease III

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Functionally unrelated signalling proteins contain a fold similar to Mg2+-dependent endonucleases

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

1 reference

7 January 2021

Incision activity of human apurinic endonuclease (Ape) at abasic site analogs in DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Elements in abasic site recognition by the major human and Escherichia coli apurinic/apyrimidinic endonucleases

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Mechanism of DNA cleavage and substrate recognition by a bovine apurinic endonuclease.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

The role of Mg2+ and specific amino acid residues in the catalytic reaction of the major human abasic endonuclease: new insights from EDTA-resistant incision of acyclic abasic site analogs and site-directed mutagenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Dynamics of the interaction of human apurinic endonuclease (Ape1) with its substrate and product

1 reference

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7 January 2021

Cleavage of single- and double-stranded DNAs containing an abasic residue by Escherichia coli exonuclease III (AP endonuclease VI)

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Specific recognition of apurinic sites in DNA by a tryptophan-containing peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Abasic site recognition mechanism by the Escherichia coli exonuclease III.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Conformations of nicked and gapped DNA structures by NMR and molecular dynamic simulations in water

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Substrate binding by human apurinic/apyrimidinic endonuclease indicates a Briggs-Haldane mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Abasic site binding by the human apurinic endonuclease, Ape, and determination of the DNA contact sites

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Human apurinic/apyrimidinic endonuclease is processive

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Abasic site recognition by two apurinic/apyrimidinic endonuclease families in DNA base excision repair: the 3' ends justify the means

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Conversion of bovine pancreatic DNase I to a repair endonuclease with a high selectivity for abasic sites

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Mapping the protein-DNA interface and the metal-binding site of the major human apurinic/apyrimidinic endonuclease

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Human L1 retrotransposon encodes a conserved endonuclease required for retrotransposition

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Targeting of human retrotransposon integration is directed by the specificity of the L1 endonuclease for regions of unusual DNA structure.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

DNA recognition by DNase I.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

The open reading frame 1 of the L1Tc retrotransposon of Trypanosoma cruzi codes for a protein with apurinic-apyrimidinic nuclease activity

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Characterization of a non-long terminal repeat retrotransposon cDNA (L1Tc) from Trypanosoma cruzi: homology of the first ORF with the ape family of DNA repair enzymes.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Exonuclease III and endonuclease IV remove 3' blocks from DNA synthesis primers in H2O2-damaged Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Site-directed mutagenesis of the human DNA repair enzyme HAP1: identification of residues important for AP endonuclease and RNase H activity

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Conserved domains in DNA repair proteins and evolution of repair systems

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Structure of the DNA repair enzyme endonuclease IV and its DNA complex: double-nucleotide flipping at abasic sites and three-metal-ion catalysis

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Endonuclease-resistant apyrimidinic sites formed by neocarzinostatin at cytosine residues in DNA: evidence for a possible role in mutagenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Bleomycin-treated DNA is specifically cleaved only by endonuclease IV in E. coli

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Recognition of oxidized abasic sites by repair endonucleases

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Alpha-deoxyadenosine, a major anoxic radiolysis product of adenine in DNA, is a substrate for Escherichia coli endonuclease IV.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

In vitro detection of endonuclease IV-specific DNA damage formed by bleomycin in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Differential cleavage of oligonucleotides containing the benzene-derived adduct, 1,N6-benzetheno-dA, by the major human AP endonuclease HAP1 and Escherichia coli exonuclease III and endonuclease IV.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Evidence for a common active site for cleavage of an AP site and the benzene-derived exocyclic adduct, 3,N4-benzetheno-dC, in the major human AP endonuclease

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Intragenic suppression of an active site mutation in the human apurinic/apyrimidinic endonuclease

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Identification of critical active-site residues in the multifunctional human DNA repair enzyme HAP1.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Rapid dissociation of human apurinic endonuclease (Ape1) from incised DNA induced by magnesium

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Single-turnover analysis of mutant human apurinic/apyrimidinic endonuclease

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Metal Activation of Enzymes in Nucleic Acid Biochemistry

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

X-ray structure of the DNase I-d(GGTATACC)2 complex at 2.3 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Substitution of Asp-210 in HAP1 (APE/Ref-1) eliminates endonuclease activity but stabilises substrate binding.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Site-directed mutagenesis of the catalytic residues of bovine pancreatic deoxyribonuclease I.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Structural basis for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Human thymine DNA glycosylase binds to apurinic sites in DNA but is displaced by human apurinic endonuclease 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Thermodynamics of human DNA ligase I trimerization and association with DNA polymerase beta

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Functional sites of interaction between release factor RF1 and the ribosome

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Redox regulation of fos and jun DNA-binding activity in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Characterization of the DNA-binding properties of the early growth response-1 (Egr-1) transcription factor: evidence for modulation by a redox mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Identification of redox/repair protein Ref-1 as a potent activator of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

A redox mechanism controls differential DNA binding activities of hypoxia-inducible factor (HIF) 1alpha and the HIF-like factor.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

An 'environment to nucleus' signaling system operates in B lymphocytes: redox status modulates BSAP/Pax-5 activation through Ref-1 nuclear translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

The solution structure of human thioredoxin complexed with its target from Ref-1 reveals peptide chain reversal

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

The redox and DNA-repair activities of Ref-1 are encoded by nonoverlapping domains

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Deletion analysis of human AP-endonuclease: minimum sequence required for the endonuclease activity

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Expression and subcellular localization of human AP endonuclease 1 (HAP1/Ref-1) protein: a basis for its role in human disease

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Phosphorylation of the DNA repair protein APE/REF-1 by CKII affects redox regulation of AP-1

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Identification of residues in the human DNA repair enzyme HAP1 (Ref-1) that are essential for redox regulation of Jun DNA binding

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

The interaction between Ku antigen and REF1 protein mediates negative gene regulation by extracellular calcium

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Negative regulation of the major human AP-endonuclease, a multifunctional protein

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Oxidants as stimulators of signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Going APE over ref-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

A murine AP-endonuclease gene-targeted deficiency with post-implantation embryonic progression and ionizing radiation sensitivity.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

A role for the human DNA repair enzyme HAP1 in cellular protection against DNA damaging agents and hypoxic stress

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Biological Responses of Human Apurinic Endonuclease to Radiation‐Induced DNA Damage

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Stable expression in rat glioma cells of sense and antisense nucleic acids to a human multifunctional DNA repair enzyme, APEX nuclease.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Endonuclease IV (nfo) mutant of Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Cellular role of yeast Apn1 apurinic endonuclease/3'-diesterase: repair of oxidative and alkylation DNA damage and control of spontaneous mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

AP endonuclease activity in humans: Development of a simple assay and analysis of ten normal individuals

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Genetic interaction between HAP1/REF-1 and p53

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Mutant AP endonuclease in patients with amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Evidence of reduced DNA repair in amyotrophic lateral sclerosis brain tissue.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Molecular genetic analysis of the APEX nuclease gene in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Screening of AP endonuclease as a candidate gene for amyotrophic lateral sclerosis (ALS)

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Functional characterization of Ape1 variants identified in the human population

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Human AP endonuclease 1 (HAP1) protein expression in breast cancer correlates with lymph node status and angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Nuclear localization of human AP endonuclease 1 (HAP1/Ref-1) associates with prognosis in early operable non-small cell lung cancer (NSCLC).

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Overlapping specificities of base excision repair, nucleotide excision repair, recombination, and translesion synthesis pathways for DNA base damage in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Damage repertoire of the Escherichia coli UvrABC nuclease complex includes abasic sites, base-damage analogues, and lesions containing adjacent 5' or 3' nicks

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

In vitro repair of oxidative DNA damage by human nucleotide excision repair system: possible explanation for neurodegeneration in xeroderma pigmentosum patients

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Evidence for the involvement of nucleotide excision repair in the removal of abasic sites in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Mechanism of UV endonuclease V cleavage of abasic sites in DNA determined by carbon-13 labeling

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Life without DNA repair

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Mammalian base excision repair and DNA polymerase beta

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Base excision repair in yeast and mammals

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Suppression of spontaneous mutagenesis in human cells by DNA base excision-repair

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

XRCC1 keeps DNA from getting stranded

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Poly(ADP-ribose) polymerase-1: what have we learned from the deficient mouse model?

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Crystallographic refinement and structure of DNase I at 2 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

VMD: visual molecular dynamics

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Raster3D: photorealistic molecular graphics

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Schizosaccharomyces pombe apn1 encodes a homologue of the Escherichia coli endonuclease IV family of DNA repair proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

Analysis of the genome sequence of the flowering plant Arabidopsis thaliana

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2801%2900063-5

7 January 2021

10.1016/S0921-8777(01)00063-5

Identifiers

DOI

1 reference

1 August 2017

1 reference

PubMed ID

11585362