Structure-activity relationships in human Toll-like receptor 8-active 2,3-diamino-furo[2,3-c]pyridines. (Q34394100)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22924757%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

title

Structure-activity relationships in human Toll-like receptor 8-active 2,3-diamino-furo[2,3-c]pyridines (English)

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12 February 2020

0 references

1

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12 February 2020

Xinkun Wang

8

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12 February 2020

author name string

Euna Yoo

2

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12 February 2020

Nikunj M Shukla

3

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12 February 2020

Rajalakshmi Balakrishna

4

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12 February 2020

Subbalakshmi S Malladi

5

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12 February 2020

Katelyn J Serafin

6

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12 February 2020

Victor W Day

7

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12 February 2020

Sunil A David

9

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12 February 2020

language of work or name

English

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publication date

7 September 2012

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Journal of Medicinal Chemistry

12 February 2020

published in

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12 February 2020

volume

55

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12 February 2020

issue

18

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12 February 2020

page(s)

8137-8151

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Rethinking molecular similarity: comparing compounds on the basis of biological activity.

12 February 2020

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Review: Structural determinants of pattern recognition by lung collectins.

6 July 2018

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Immunoprofiling toll-like receptor ligands: Comparison of immunostimulatory and proinflammatory profiles in ex vivo human blood models.

6 July 2018

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Structure-activity relationships in toll-like receptor-2 agonistic diacylthioglycerol lipopeptides

6 July 2018

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Synthesis and biological evaluation of 8-oxoadenine derivatives as toll-like receptor 7 agonists introducing the antedrug concept

6 July 2018

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Regulation of adaptive immunity by the innate immune system

6 July 2018

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Pattern recognition by pentraxins

6 July 2018

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Regioisomerism-dependent TLR7 agonism and antagonism in an imidazoquinoline

6 July 2018

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Potential adjuvantic properties of innate immune stimuli

6 July 2018

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6 July 2018

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Structures of TLR-ligand complexes

6 July 2018

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6 July 2018

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Comparison of the immunostimulatory and proinflammatory activities of candidate Gram-positive endotoxins, lipoteichoic acid, peptidoglycan, and lipopeptides, in murine and human cells

6 July 2018

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Structural Basis of Toll-Like Receptor 3 Signaling with Double-Stranded RNA

6 July 2018

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Ficolins: novel pattern recognition molecules of the innate immune response

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: Activation of Toll-like receptor 7

6 July 2018

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6 July 2018

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6 July 2018

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Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

6 July 2018

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Toll-like receptors: critical proteins linking innate and acquired immunity

6 July 2018

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Toll-like receptors and innate immunity.

6 July 2018

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Selective transmission of R5-tropic HIV type 1 from dendritic cells to resting CD4+ T cells

6 July 2018

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Comparation interferon- inducing and antiviral properties of 2-amino-5-bromo-6-methyl-4-pyrimidinol (U-25,166), tilorone hydrochloride, and polyinosinic-polycytidylic acid

6 July 2018

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Structure-activity relationships in human Toll-like receptor 2-specific monoacyl lipopeptides.

6 July 2018

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2-Azidoalkoxy-7-hydro-8-oxoadenine derivatives as TLR7 agonists inducing dendritic cell maturation

27 October 2018

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Scaffold hopping in drug discovery using inductive logic programming.

27 October 2018

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Distinct indirect pathways govern human NK-cell activation by TLR-7 and TLR-8 agonists.

27 October 2018

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Synthesis and structure-activity relationships of 2-substituted-8-hydroxyadenine derivatives as orally available interferon inducers without emetic side effects

27 October 2018

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Discovery of 8-hydroxyadenines as a novel type of interferon inducer

27 October 2018

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Structure-activity relationship of synthetic toll-like receptor 4 agonists

27 October 2018

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12 December 2020

Comparison between Circulating Interferon and Drug Levels Following Administration of 2-amino-5-bromo-6-phenyl-4(3H)-Pyrimidinone (ABPP) to Different Animal Species

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Lipid A, the endotoxic center of bacterial lipopolysaccharides: relation of chemical structure to biological activity

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TLR2 engagement on CD8 T cells lowers the thresholdfor optimal antigen-induced T cell activation

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12 December 2020

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12 December 2020

Vaccine adjuvant activity of 3M-052: an imidazoquinoline designed for local activity without systemic cytokine induction

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12 December 2020

Identifiers

DOI

10.1021/JM301066H

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22924757%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22924757%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference