mTOR target NDRG1 confers MGMT-dependent resistance to alkylating chemotherapy (Q34394233)

1 August 2017

mTOR target NDRG1 confers MGMT-dependent resistance to alkylating chemotherapy (English)

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1 August 2017

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23

Andreas von Deimling

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Martin Bendszus

22

Martin Bendszus

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Lukas Bunse

Lukas Bunse

7

0 references

Felix Sahm

Felix Sahm

4

0 references

Stefan Pusch

Stefan Pusch

3

0 references

Michael Platten

Michael Platten

27

0 references

Michael Weller

25

Michael Weller

1 reference

1 August 2017

28

Wolfgang Wick

1 reference

1 August 2017

19

Martina Schnölzer

1 reference

1 August 2017

5

Marcus Czabanka

1 reference

1 August 2017

26

Peter Vajkoczy

1 reference

1 August 2017

2

Jonas Blaes

1 reference

1 August 2017

8

Gergely Solecki

1 reference

1 August 2017

9

Viktoria Eichwald

1 reference

1 August 2017

10

Manfred Jugold

1 reference

1 August 2017

12

Matthias Osswald

1 reference

1 August 2017

14

Thomas Hielscher

1 reference

1 August 2017

15

Petra Rübmann

1 reference

1 August 2017

18

Tore Kempf

1 reference

1 August 2017

Michael W Ronellenfitsch

17

Michael Ronellenfitsch

1 reference

1 August 2017

Markus Weiler

1

1 reference

1 August 2017

Sebastian Luger

6

1 reference

1 August 2017

Sibylle Hodecker

11

1 reference

1 August 2017

Christoph Meisner

13

1 reference

1 August 2017

Philipp-Niklas Pfenning

16

1 reference

1 August 2017

Amir Abdollahi

20

1 reference

1 August 2017

Florian Lang

21

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1 August 2017

Frank Winkler

24

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1 August 2017

language of work or name

English

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publication date

23 December 2013

1 reference

Proceedings of the National Academy of Sciences of the United States of America

1 August 2017

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1 August 2017

111

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1 August 2017

1

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1 August 2017

409-414

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Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial

1 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890826

Suppression of proinvasive RGS4 by mTOR inhibition optimizes glioma treatment

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890826

Emerging insights into the molecular and cellular basis of glioblastoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890826

NDRG1/Cap43/Drg-1 may predict tumor angiogenesis and poor outcome in patients with lung cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890826

Oncogenic EGFR signaling activates an mTORC2-NF-κB pathway that promotes chemotherapy resistance

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890826

The N-myc downstream regulated gene (NDRG) family: diverse functions, multiple applications

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890826

Identification of sites subjected to serine/threonine phosphorylation by SGK1 affecting N-myc downstream-regulated gene 1 (NDRG1)/Cap43-dependent suppression of angiogenic CXC chemokine expression in human pancreatic cancer cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890826

Prolyl hydroxylases 2 and 3 act in gliomas as protective negative feedback regulators of hypoxia-inducible factors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890826

Hypoxia helps glioma to fight therapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890826

Differential dependence of hypoxia-inducible factors 1 alpha and 2 alpha on mTORC1 and mTORC2.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890826

mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890826

Mechanisms of chemoresistance to alkylating agents in malignant glioma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890826

Egr-1 mediates hypoxia-inducible transcription of the NDRG1 gene through an overlapping Egr-1/Sp1 binding site in the promoter

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890826

MGMT gene silencing and benefit from temozolomide in glioblastoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890826

Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: role of oxygenation, angiopoietin-1, and matrix metalloproteinases.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890826

Hypoxia--a key regulatory factor in tumour growth

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890826

Glucocorticoid receptor-mediated protection from apoptosis is associated with induction of the serine/threonine survival kinase gene, sgk-1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890826

Carcinogenic nickel induces genes involved with hypoxic stress

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890826

Decreased expression of NDRG1 in glioma is related to tumor progression and survival of patients.

6 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1314469111

Stable suppression of tumorigenicity by virus-mediated RNA interference

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1314469111

NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1314469111

Neuroprotection by hypoxic preconditioning requires sequential activation of vascular endothelial growth factor receptor and Akt.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3890826

27 October 2018

Identifiers

DOI

10.1073/PNAS.1314469111

1 reference

1 August 2017

0 references

1 reference

1 August 2017

1 reference