Reconstitution of intestinal CD4 and Th17 T cells in antiretroviral therapy suppressed HIV-infected subjects: implication for residual immune activation from the results of a clinical trial (Q34394987)

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English	Reconstitution of intestinal CD4 and Th17 T cells in antiretroviral therapy suppressed HIV-infected subjects: implication for residual immune activation from the results of a clinical trial	scientific article

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scholarly article

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Europe PubMed Central

1 August 2017

Reconstitution of intestinal CD4 and Th17 T cells in antiretroviral therapy suppressed HIV-infected subjects: implication for residual immune activation from the results of a clinical trial (English)

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1 August 2017

anti-retroviral agent

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Gabriella d'Ettorre

1

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7 June 2020

2

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7 June 2020

Giancarlo Ceccarelli

4

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7 June 2020

Mauro Andreotti

5

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Alessandra Mallano

11

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Clementina Maria Galluzzo

12

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Claudio M. Mastroianni

14

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Mirko Paiardini

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Mirko Paiardini

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7 June 2020

Guido Silvestri

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Guido Silvestri

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Luca Micci

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Prachi Sharma

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7 June 2020

Gianfranco Fanello

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7 June 2020

Noemi Giustini

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7 June 2020

Stefano Vella

13

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7 June 2020

Vincenzo Vullo

17

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publication date

23 October 2014

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1 August 2017

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7 June 2020

9

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7 June 2020

10

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7 June 2020

e109791

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7 June 2020

copyright license

Creative Commons Attribution 4.0 International

23 October 2014

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April 2022 Public Data File from Crossref

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Antiretroviral therapy initiated within 6 months of HIV infection is associated with lower T-cell activation and smaller HIV reservoir size

1 reference

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Impact of highly active antiretroviral therapy initiation on CD4(+) T-cell repopulation in duodenal and rectal mucosa.

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6 July 2018

Paucity of IL-21-producing CD4(+) T cells is associated with Th17 cell depletion in SIV infection of rhesus macaques

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6 July 2018

Human immunodeficiency virus and the gastrointestinal immune system: does highly active antiretroviral therapy restore gut immunity?

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SIV replication in the infected rhesus macaque is limited by the size of the preexisting TH17 cell compartment

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6 July 2018

HIV RNA suppression and immune restoration: can we do better?

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Incomplete immune recovery in HIV infection: mechanisms, relevance for clinical care, and possible solutions

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Natural SIV hosts: showing AIDS the door

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6 July 2018

Impact of time to start treatment following infection with application to initiating HAART in HIV-positive patients

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6 July 2018

Altered CD4+ T cell homing to the gut impairs mucosal immune reconstitution in treated HIV-infected individuals

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6 July 2018

Evidence for polymicrobic flora translocating in peripheral blood of HIV-infected patients with poor immune response to antiretroviral therapy

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6 July 2018

CD4+ T cells, including Th17 and cycling subsets, are intact in the gut mucosa of HIV-1-infected long-term nonprogressors

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6 July 2018

Th17 cells and regulatory T cells in elite control over HIV and SIV.

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HIV-associated immune activation: from bench to bedside

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6 July 2018

Differences in HIV burden and immune activation within the gut of HIV-positive patients receiving suppressive antiretroviral therapy

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6 July 2018

Disruption of intestinal CD4+ T cell homeostasis is a key marker of systemic CD4+ T cell activation in HIV-infected individuals

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6 July 2018

Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections

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6 July 2018

Microbial translocation induces persistent macrophage activation unrelated to HIV-1 levels or T-cell activation following therapy

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6 July 2018

Th17, gut, and HIV: therapeutic implications

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6 July 2018

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6 July 2018

Th17 cells in natural SIV hosts

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6 July 2018

Th17 lineage commitment and HIV-1 pathogenesis

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Th17 and regulatory T cells: implications for AIDS pathogenesis

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Th17 cytokines in mucosal immunity and inflammation

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Susceptibility of human Th17 cells to human immunodeficiency virus and their perturbation during infection.

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6 July 2018

Cycling of gut mucosal CD4+ T cells decreases after prolonged anti-retroviral therapy and is associated with plasma LPS levels

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6 July 2018

Early initiation of highly active antiretroviral therapy fails to reverse immunovirological abnormalities in gut-associated lymphoid tissue induced by acute HIV infection

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6 July 2018

Transient nature of long-term nonprogression and broad virus-specific proliferative T-cell responses with sustained thymic output in HIV-1 controllers

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6 July 2018

Plasma levels of bacterial DNA correlate with immune activation and the magnitude of immune restoration in persons with antiretroviral-treated HIV infection

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6 July 2018

Critical loss of the balance between Th17 and T regulatory cell populations in pathogenic SIV infection

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6 July 2018

HIV infection, antiretroviral treatment, ageing, and non-AIDS related morbidity

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6 July 2018

Delayed loss of control of plasma lipopolysaccharide levels after therapy interruption in chronically HIV-1-infected patients.

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6 July 2018

Altered balance between Th17 and Th1 cells at mucosal sites predicts AIDS progression in simian immunodeficiency virus-infected macaques

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6 July 2018

Inflammatory and coagulation biomarkers and mortality in patients with HIV infection

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6 July 2018

Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections

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6 July 2018

Life expectancy of individuals on combination antiretroviral therapy in high-income countries: a collaborative analysis of 14 cohort studies

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6 July 2018

Th17 cells in human disease.

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6 July 2018

Changes in the risk of death after HIV seroconversion compared with mortality in the general population

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6 July 2018

Simian immunodeficiency virus-induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut.

1 reference

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6 July 2018

Differentiation and function of Th17 T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207675

6 July 2018

Lack of mucosal immune reconstitution during prolonged treatment of acute and early HIV-1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207675

6 July 2018

Microbial translocation is a cause of systemic immune activation in chronic HIV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207675

6 July 2018

Viral suppression and immune restoration in the gastrointestinal mucosa of human immunodeficiency virus type 1-infected patients initiating therapy during primary or chronic infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207675

6 July 2018

HIV disease: fallout from a mucosal catastrophe?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207675

6 July 2018

Early antiretroviral therapy for simian immunodeficiency virus infection leads to mucosal CD4+ T-cell restoration and enhanced gene expression regulating mucosal repair and regeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207675

6 July 2018

Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy

1 reference

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6 July 2018

Immune activation, apoptosis, and Treg activity are associated with persistently reduced CD4+ T-cell counts during antiretroviral therapy.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0109791

21 January 2018

Impaired CD4+ T-cell restoration in the small versus large intestine of HIV-1-positive South Africans receiving combination antiretroviral therapy.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0109791

21 January 2018

Sigmoid Th17 populations, the HIV latent reservoir, and microbial translocation in men on long-term antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0109791

21 January 2018

[Helper T cell paradigm: Th17 and regulatory T cells involved in autoimmune inflammatory disorders, pathogen defense and allergic diseases].

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0109791

21 January 2018

HIV-1 infection is characterized by profound depletion of CD161+ Th17 cells and gradual decline in regulatory T cells.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0109791

21 January 2018

Effective CD4+ T-cell restoration in gut-associated lymphoid tissue of HIV-infected patients is associated with enhanced Th17 cells and polyfunctional HIV-specific T-cell responses

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0109791

21 January 2018

Microbial translocation is associated with residual viral replication in HAART-treated HIV+ subjects with <50copies/ml HIV-1 RNA.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0109791

21 January 2018

HIV Persistence in the Gut Mucosa of HIV-Infected Subjects Undergoing Antiretroviral Therapy Correlates with Immune Activation and Increased Levels of LPS

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0109791

21 January 2018

Evidence for a cross-talk between human neutrophils and Th17 cells

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0109791

21 January 2018

Low Level of Regulatory T Cells and Maintenance of Balance Between Regulatory T Cells and TH17 Cells in HIV-1–Infected Elite Controllers

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0109791

21 January 2018

Immune reconstitution in the sigmoid colon after long-term HIV therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25340778

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term non-progressors display a greater number of Th17 cells than HIV-infected typical progressors

1 reference

https://pubmed.ncbi.nlm.nih.gov/25340778

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[HIV controllers: a homogeneous group of HIV-1 infected patients with a spontaneous control of viral replication]

1 reference

https://pubmed.ncbi.nlm.nih.gov/25340778

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0109791

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25340778%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

2014PLoSO...9j9791D

0 references

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25340778%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference

Europe PubMed Central

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7 June 2020

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