Huh-7 or HepG2 cells: which is the better model for studying human apolipoprotein-B100 assembly and secretion? (Q34395165)

1 August 2017

title

Huh-7 or HepG2 cells: which is the better model for studying human apolipoprotein-B100 assembly and secretion? (English)

1 reference

1 August 2017

Janet D Sparks

3

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Edward A Fisher

object named as

Edward A Fisher

series ordinal

4

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author name string

Steven J R Meex

series ordinal

1

1 reference

1 August 2017

Ursula Andreo

series ordinal

2

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1 August 2017

publication date

18 October 2010

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1 August 2017

number of pages

7

1 reference

Journal of Lipid Research

inferred from page(s)

published in

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1 August 2017

volume

52

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1 August 2017

issue

1

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1 August 2017

page(s)

152-158

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The ever-expanding role of degradation in the regulation of apolipoprotein B metabolism

1 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2999930

The many intersecting pathways underlying apolipoprotein B secretion and degradation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2999930

Lipids, lipoproteins, and apolipoproteins as risk markers of myocardial infarction in 52 countries (the INTERHEART study): a case-control study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2999930

Lipid droplets are arrested in the ER membrane by tight binding of lipidated apolipoprotein B-100.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2999930

MEK-ERK inhibition corrects the defect in VLDL assembly in HepG2 cells: potential role of ERK in VLDL-ApoB100 particle assembly

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2999930

Cotranslocational degradation protects the stressed endoplasmic reticulum from protein overload

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2999930

Cytoplasmic lipid droplets are sites of convergence of proteasomal and autophagic degradation of apolipoprotein B.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2999930

Wild-type PCSK9 inhibits LDL clearance but does not affect apoB-containing lipoprotein production in mouse and cultured cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2999930

Lipid peroxidation and oxidant stress regulate hepatic apolipoprotein B degradation and VLDL production

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2999930

The inhibition of microsomal triglyceride transfer protein activity in rat hepatoma cells promotes proteasomal and nonproteasomal degradation of apoprotein b100.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2999930

Distribution of microsomal triglyceride transfer protein within sub-endoplasmic reticulum regions in human hepatoma cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2999930

Complexity in the secretory pathway: the assembly and secretion of apolipoprotein B-containing lipoproteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2999930

The late addition of core lipids to nascent apolipoprotein B100, resulting in the assembly and secretion of triglyceride-rich lipoproteins, is independent of both microsomal triglyceride transfer protein activity and new triglyceride synthesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2999930

Apoprotein B100 has a prolonged interaction with the translocon during which its lipidation and translocation change from dependence on the microsomal triglyceride transfer protein to independence.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2999930

Myristic acid increases dense lipoprotein secretion by inhibiting apoB degradation and triglyceride recruitment

6 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1194%2FJLR.D008888

Transmembrane lipid transfer is crucial for providing neutral lipids during very low density lipoprotein assembly in endoplasmic reticulum

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1194%2FJLR.D008888

Regulated Co-translational ubiquitination of apolipoprotein B100. A new paradigm for proteasomal degradation of a secretory protein

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2999930

The degradation of apolipoprotein B100 is mediated by the ubiquitin-proteasome pathway and involves heat shock protein 70

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2999930

Ubiquitin-proteasome pathway mediates intracellular degradation of apolipoprotein B

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20956548

12 December 2020

inferred from PubMed ID database lookup

Co-translational degradation of apolipoprotein B100 by the proteasome is prevented by microsomal triglyceride transfer protein. Synchronized translation studies on HepG2 cells treated with an inhibitor of microsomal triglyceride transfer protein

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20956548

12 December 2020

inferred from PubMed ID database lookup

An MTP inhibitor that normalizes atherogenic lipoprotein levels in WHHL rabbits

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20956548

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1194/JLR.D008888

1 reference

1 August 2017

1 reference

1 August 2017

1 reference