Lipid biosynthesis as a target for antibacterial agents (Q34395560)

1 August 2017

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title

Lipid biosynthesis as a target for antibacterial agents (English)

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1 August 2017

Heath RJ

1

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1 August 2017

White SW

series ordinal

2

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1 August 2017

Rock CO

series ordinal

3

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1 August 2017

publication date

1 November 2001

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Progress in Lipid Research

1 August 2017

published in

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1 August 2017

volume

40

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1 August 2017

issue

6

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1 August 2017

page(s)

467-497

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Escherichia coli as a model for the regulation of dissociable (type II) fatty acid biosynthesis

1 August 2017

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Preparation and antibacterial activities of new 1,2,3-diazaborine derivatives and analogues

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Boron-containing antibacterial agents: effects on growth and morphology of bacteria under various culture conditions

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Inhibitor binding studies on enoyl reductase reveal conformational changes related to substrate recognition

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Crystal structure of the Mycobacterium tuberculosis enoyl-ACP reductase, InhA, in complex with NAD+ and a C16 fatty acyl substrate

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The X-ray structure of Escherichia coli enoyl reductase with bound NAD+ at 2.1 A resolution

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Molecular genetic analysis of enoyl-acyl carrier protein reductase inhibition by diazaborine.

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7 January 2021

Enzymatic characterization of the target for isoniazid in Mycobacterium tuberculosis

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7 January 2021

Kinetic mechanism of NADH-enoyl-ACP reductase from Brassica napus.

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7 January 2021

Triclosan: applications and safety

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Triclosan targets lipid synthesis

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7 January 2021

Mechanism of triclosan inhibition of bacterial fatty acid synthesis

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Kinetic and structural characteristics of the inhibition of enoyl (acyl carrier protein) reductase by triclosan

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7 January 2021

Molecular basis of triclosan activity

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Structural basis and mechanism of enoyl reductase inhibition by triclosan

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7 January 2021

Crystallographic analysis of triclosan bound to enoyl reductase

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7 January 2021

Molecular basis for triclosan activity involves a flipping loop in the active site

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Isoniazid Inhibition of the Synthesis of Monounsaturated Long-Chain Fatty Acids in Mycobacterium tuberculosis H37Ra

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7 January 2021

Inhibition of a Mycobacterium tuberculosis beta-ketoacyl ACP synthase by isoniazid.

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Thiolactomycin and related analogues as novel anti-mycobacterial agents targeting KasA and KasB condensing enzymes in Mycobacterium tuberculosis

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Triclosan offers protection against blood stages of malaria by inhibiting enoyl-ACP reductase of Plasmodium falciparum

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7 January 2021

The X-ray crystal structure of beta-ketoacyl [acyl carrier protein] synthase I

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Crystal structure of beta-ketoacyl-acyl carrier protein synthase II from E.coli reveals the molecular architecture of condensing enzymes

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7 January 2021

Structure of the complex between the antibiotic cerulenin and its target, beta-ketoacyl-acyl carrier protein synthase

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7 January 2021

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7 January 2021

Substitution of cellular fatty acids in yeast cells by the antibiotic cerulenin and exogenous fatty acids

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7 January 2021

Cerulenin-inhibited cells of Staphylococcus aureus resume growth when supplemented with either a saturated or an unsaturated fatty acid

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7 January 2021

Cerulenin effect on phospholipid metabolism in Mycobacterium smegmatis ATCC 607

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7 January 2021

Inhibition of unsaturated fatty acid synthesis in Escherichia coli by the antibiotic cerulenin

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7 January 2021

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7 January 2021

Inhibition of fatty acid synthetases by the antibiotic cerulenin

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7 January 2021

Thiolactomycin, a new antibiotic. II. Structure elucidation

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7 January 2021

Structure of thiolactomycin

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7 January 2021

Thiolactomycin, a new antibiotic. I. Taxonomy of the producing organism, fermentation and biological properties.

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7 January 2021

Thiolactomycin, a new antibiotic. III. In vitro antibacterial activity.

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7 January 2021

Antimicrobial activities of thiolactomycin against gram-negative anaerobes associated with periodontal disease. f1

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7 January 2021

Specialized fatty acid synthesis in African trypanosomes: myristate for GPI anchors

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7 January 2021

Thiolactomycin, a new antibiotic. IV. Biological properties and chemotherapeutic activity in mice.

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Overproduction of beta-ketoacyl-acyl carrier protein synthase I imparts thiolactomycin resistance to Escherichia coli K-12

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https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

Effect of thiolactomycin on the individual enzymes of the fatty acid synthase system in Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

Novel inhibitors of the condensing enzymes of the type II fatty acid synthase of pea (Pisum sativum).

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

On the mode of interaction of -hydroxydecanoyl thioester dehydrase with allenic acid derivatives

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

Structure of a dehydratase-isomerase from the bacterial pathway for biosynthesis of unsaturated fatty acids: two catalytic activities in one active site

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

Suicide substrates, mechanism-based enzyme inactivators: recent developments

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

Overproduction of acetyl-CoA carboxylase activity increases the rate of fatty acid biosynthesis in Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

Synthesis of a reaction intermediate analogue of biotin-dependent carboxylases via a selective derivatization of biotin

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

Inhibition of biotin carboxylase by a reaction intermediate analog: implications for the kinetic mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

Three-dimensional structure of the biotin carboxylase subunit of acetyl-CoA carboxylase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

Movement of the biotin carboxylase B-domain as a result of ATP binding

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

Antibacterial activity of phenolic compounds and aromatic alcohols

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

Antibacterial activity of phenethyl alcohol and resulting membrane alterations

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

Effects of temperature variation and phenethyl alcohol addition on acyl chain order and lipid organization in Escherichia coli derived membrane systems. A 2H- and 31P-NMR study

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

Effects of Phenethyl Alcohol on Phospholipid Metabolism in Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

Fatty acid synthesis in Escherichia coli is indirectly inhibited by phenethyl alcohol

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

Purification and reconstitution of murine mitochondrial glycerol-3-phosphate acyltransferase. Functional expression in baculovirus-infected insect cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

A gene (plsD) from Clostridium butyricum that functionally substitutes for the sn-glycerol-3-phosphate acyltransferase gene (plsB) of Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

Analysis of amino acid motifs diagnostic for the sn-glycerol-3-phosphate acyltransferase reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

sn-Glycerol-3-phosphate auxotrophy of plsB strains of Escherichia coli: evidence that a second mutation, plsX, is required

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

Antibacterial agents that inhibit lipid A biosynthesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

Antibacterial agents that target lipid A biosynthesis in gram-negative bacteria. Inhibition of diverse UDP-3-O-(r-3-hydroxymyristoyl)-n-acetylglucosamine deacetylases by substrate analogs containing zinc binding motifs

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

A left-handed parallel beta helix in the structure of UDP-N-acetylglucosamine acyltransferase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

The effect of diflufenican on lipid metabolism in plants

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

Clinical Experiences in Cases of Primary Tuberculosis with Tuberculostaticum Isoxyl

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

Isoxyl: A Review of the Results of its Use Over a Five-Year Period in the Tuberculosis Field Service of a Large Urban Area

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

Effects of Ethionamide and Isoxyl on Mycolic Acid Synthesis in Mycobacterium tuberculosis bcg

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

Antimycobacterial activities of isoxyl and new derivatives through the inhibition of mycolic acid synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

Cloning, sequencing, and expression of the pantothenate kinase (coaA) gene of Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

Cloning and characterization of a eukaryotic pantothenate kinase gene (panK) from Aspergillus nidulans

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

Pantothenate kinase regulation of the intracellular concentration of coenzyme A.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

Cloning, overproduction, and characterization of the Escherichia coli holo-acyl carrier protein synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

Biochemical and molecular analyses of the Streptococcus pneumoniae acyl carrier protein synthase, an enzyme essential for fatty acid biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

Crystal structure of Streptococcus pneumoniae acyl carrier protein synthase: an essential enzyme in bacterial fatty acid biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

Crystal structures of substrate binding to Bacillus subtilis holo-(acyl carrier protein) synthase reveal a novel trimeric arrangement of molecules resulting in three active sites

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

Identification and analysis of the acyl carrier protein (ACP) docking site on beta-ketoacyl-ACP synthase III

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

The X-ray structure of Brassica napus beta-keto acyl carrier protein reductase and its implications for substrate binding and catalysis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900012-1

7 January 2021

10.1016/S0163-7827(01)00012-1

Identifiers

DOI

1 reference

1 August 2017

1 reference