Elevated circulating Sclerostin concentrations in individuals with high bone mass, with and without LRP5 mutations. (Q34396458)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24606091%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

title

Elevated circulating Sclerostin concentrations in individuals with high bone mass, with and without LRP5 mutations (English)

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9 March 2020

1

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9 March 2020

Emma L. Duncan

4

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9 March 2020

Joern Rittweger

5

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9 March 2020

Jon H Tobias

8

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9 March 2020

7

George Davey Smith

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9 March 2020

3

Eugene V McCloskey

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9 March 2020

author name string

Kenneth E S Poole

2

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9 March 2020

William D Fraser

6

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9 March 2020

language of work or name

English

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publication date

25 February 2014

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The Journal of Clinical Endocrinology and Metabolism

9 March 2020

published in

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9 March 2020

volume

99

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9 March 2020

page(s)

2897-2907

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9 March 2020

issue

8

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Association of circulating sclerostin with bone mineral mass, microstructure, and turnover biochemical markers in healthy elderly men and women

9 March 2020

cites work

1 reference

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Sclerostin and bone strength in women in their 10th decade of life

6 July 2018

1 reference

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WNT signaling in bone homeostasis and disease: from human mutations to treatments

6 July 2018

1 reference

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High bone mass is associated with an increased prevalence of joint replacement: a case-control study

6 July 2018

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Analysis of body composition in individuals with high bone mass reveals a marked increase in fat mass in women but not men

6 July 2018

1 reference

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The high bone mass phenotype is characterised by a combined cortical and trabecular bone phenotype: findings from a pQCT case-control study

6 July 2018

1 reference

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Serum sclerostin increases in healthy adult men during bed rest.

6 July 2018

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A multinational study to develop universal standardization of whole-body bone density and composition using GE Healthcare Lunar and Hologic DXA systems

6 July 2018

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Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

6 July 2018

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Weight loss in obese older adults increases serum sclerostin and impairs hip geometry but both are prevented by exercise training

6 July 2018

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Genome-wide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk

6 July 2018

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'Sink or swim': an evaluation of the clinical characteristics of individuals with high bone mass

6 July 2018

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Levels of serotonin, sclerostin, bone turnover markers as well as bone density and microarchitecture in patients with high-bone-mass phenotype due to a mutation in Lrp5

6 July 2018

1 reference

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Relation of age, gender, and bone mass to circulating sclerostin levels in women and men.

6 July 2018

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Effects of parathyroid hormone treatment on circulating sclerostin levels in postmenopausal women

6 July 2018

1 reference

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Regulation of circulating sclerostin levels by sex steroids in women and in men.

6 July 2018

1 reference

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Does standardized BMD still remove differences between Hologic and GE-Lunar state-of-the-art DXA systems?

6 July 2018

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Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions

6 July 2018

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Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin

6 July 2018

1 reference

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Recommendations for thresholds for cortical bone geometry and density measurement by peripheral quantitative computed tomography

6 July 2018

1 reference

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Sclerostin is a delayed secreted product of osteocytes that inhibits bone formation

6 July 2018

1 reference

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High bone mass in mice expressing a mutant LRP5 gene

6 July 2018

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A 52-kb deletion in the SOST-MEOX1 intergenic region on 17q12-q21 is associated with van Buchem disease in the Dutch population

6 July 2018

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Identification of a 52 kb deletion downstream of the SOST gene in patients with van Buchem disease

6 July 2018

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Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST)

6 July 2018

1 reference

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Validation in London of a physical activity questionnaire for use in a study of postmenopausal osteopaenia

6 July 2018

1 reference

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The assessment of historical physical activity and its relation to adult bone parameters

6 July 2018

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Comparative effect of zoledronic acid versus denosumab on serum sclerostin and dickkopf-1 levels of naive postmenopausal women with low bone mass: a randomized, head-to-head clinical trial

6 July 2018

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Acute effects of glucocorticoids on serum markers of osteoclasts, osteoblasts, and osteocytes

27 October 2018

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Lower fracture risk in older men with higher sclerostin concentration: a prospective analysis from the MINOS study.

27 October 2018

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Physical activity in relation to serum sclerostin, insulin-like growth factor-1, and bone turnover markers in healthy premenopausal women: a cross-sectional and a longitudinal study

27 October 2018

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Sclerostin levels associated with inhibition of the Wnt/β-catenin signaling and reduced bone turnover in type 2 diabetes mellitus

27 October 2018

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Association of circulating sclerostin levels with fat mass and metabolic disease--related markers in Japanese postmenopausal women.

27 October 2018

1 reference

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Long-term treatment with raloxifene, but not bisphosphonates, reduces circulating sclerostin levels in postmenopausal women.

27 October 2018

1 reference

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Sclerostin mediates bone response to mechanical unloading through antagonizing Wnt/beta-catenin signaling.

27 October 2018

1 reference

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The International Physical Activity Questionnaire (IPAQ): a study of concurrent and construct validity.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207929

Reproducibility of a self-administered lifetime physical activity questionnaire among female college alumnae.

27 October 2018

1 reference

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Universal standardization of bone density measurements: a method with optimal properties for calibration among several instruments.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207929

Patients with sclerosteosis and disease carriers: human models of the effect of sclerostin on bone turnover

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207929

Standardization of femur BMD

27 October 2018

1 reference

12 December 2020

Determinants of serum sclerostin in healthy pre- and postmenopausal women

1 reference

12 December 2020

Circulating Levels of Sclerostin Are Increased in Patients with Type 2 Diabetes Mellitus

1 reference

12 December 2020

Serum sclerostin levels positively correlate with lumbar spinal bone mineral density in postmenopausal women--the six-month effect of risedronate and teriparatide

1 reference

12 December 2020

Sclerostin and DKK1 levels during 14 and 21 days of bed rest in healthy young men

1 reference

12 December 2020

Correlates of bone microarchitectural parameters and serum sclerostin levels in men: the STRAMBO study

1 reference

12 December 2020

RELIABILITY AND VALIDITY OF THE INTERNATIONAL PHYSICAL ACTIVITY QUESTIONNAIRE (IPAQ)

1 reference

12 December 2020

Targeted ablation of osteocytes induces osteoporosis with defective mechanotransduction

1 reference

12 December 2020

Increased sclerostin serum levels associated with bone formation and resorption markers in patients with immobilization-induced bone loss

1 reference

12 December 2020

Identifiers

DOI

10.1210/JC.2013-3958

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24606091%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24606091%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24606091%20AND%20SRC:MED&resulttype=core&format=json