The family of thiol-activated, cholesterol-binding cytolysins (Q34398264)

1 August 2017

1 reference

title

The family of thiol-activated, cholesterol-binding cytolysins (English)

1 reference

1 August 2017

Palmer M

1

1 reference

1 August 2017

1 November 2001

1 reference

1 August 2017

9

1 reference

inferred from page(s)

published in

Toxicon

1 reference

1 August 2017

39

1 reference

1 August 2017

1681-1689

1 reference

1 August 2017

11

1 reference

Streptolysin O: inhibition of the conformational change during membrane binding of the monomer prevents oligomerization and pore formation

1 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Cholesterol-binding cytolytic protein toxins

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Protein sorting in Plasmodium falciparum-infected red blood cells permeabilized with the pore-forming protein streptolysin O.

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Permeabilization of the erythrocyte membrane with streptolysin O allows access to the vacuolar membrane of Plasmodium falciparum and a molecular analysis of membrane topology.

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

pH-dependent perforation of macrophage phagosomes by listeriolysin O from Listeria monocytogenes.

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

The Toxoplasma gondii rhoptry protein ROP 2 is inserted into the parasitophorous vacuole membrane, surrounding the intracellular parasite, and is exposed to the host cell cytoplasm

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

The Arcanobacterium (Actinomyces) pyogenes hemolysin, pyolysin, is a novel member of the thiol-activated cytolysin family

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Structural analysis of the protein/lipid complexes associated with pore formation by the bacterial toxin pneumolysin

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Structure and function of pneumolysin, the multifunctional, thiol-activated toxin of Streptococcus pneumoniae

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

The potential to use PspA and other pneumococcal proteins to elicit protection against pneumococcal infection

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

The use of host cell machinery in the pathogenesis of Listeria monocytogenes.

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Secretory proteins move through the endoplasmic reticulum membrane via an aqueous, gated pore.

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

A PEST-like sequence in listeriolysin O essential for Listeria monocytogenes pathogenicity

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Effect of streptolysin O on erythrocyte membranes, liposomes, and lipid dispersions. A protein-cholesterol interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

The effect of Streptococcus pneumoniae pneumolysin on human respiratory epithelium in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Role of listeriolysin O in cell-to-cell spread of Listeria monocytogenes

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Two structural transitions in membrane pore formation by pneumolysin, the pore-forming toxin of Streptococcus pneumoniae.

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Streptococcal toxic shock syndrome: synthesis of tumor necrosis factor and interleukin-1 by monocytes stimulated with pyrogenic exotoxin A and streptolysin O.

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

The aqueous pore through the translocon has a diameter of 40-60 A during cotranslational protein translocation at the ER membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Cholesterol-Streptolysin O Interaction: An EM Study of Wild-Type and Mutant Streptolysin O.

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Mechanism of membrane insertion of a multimeric beta-barrel protein: perfringolysin O creates a pore using ordered and coupled conformational changes

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Arresting pore formation of a cholesterol-dependent cytolysin by disulfide trapping synchronizes the insertion of the transmembrane beta-sheet from a prepore intermediate

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Role of the essential thiol group in the thiol-activated cytolysin from Clostridium perfringens

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Effect of isolated C-terminal fragment of theta-toxin (perfringolysin O) on toxin assembly and membrane lysis

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Listeriolysin O: cholesterol inhibits cytolysis but not binding to cellular membranes.

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Nucleotide sequence of the streptolysin O (SLO) gene: structural homologies between SLO and other membrane-damaging, thiol-activated toxins

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Structure and molecular mechanism of a functional form of pneumolysin: a cholesterol-dependent cytolysin from Streptococcus pneumoniae

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Dissecting the molecular mechanisms of polarized membrane traffic: reconstitution of three transport steps in epithelial cells using streptolysin-O permeabilization

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Role of streptolysin O in a mouse model of invasive group A streptococcal disease

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Attenuated mutants of the intracellular bacterium Listeria monocytogenes obtained by single amino acid substitutions in listeriolysin O

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Multivalent pneumococcal capsular polysaccharide conjugate vaccines employing genetically detoxified pneumolysin as a carrier protein

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Complement activation and antibody binding by pneumolysin via a region of the toxin homologous to a human acute-phase protein

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Subunit organisation and symmetry of pore-forming, oligomeric pneumolysin

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Interaction of theta-toxin (perfringolysin O), a cholesterol-binding cytolysin, with liposomal membranes: change in the aromatic side chains upon binding and insertion

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Immunization of mice with combinations of pneumococcal virulence proteins elicits enhanced protection against challenge with Streptococcus pneumoniae

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Cold-labile hemolysin produced by limited proteolysis of theta-toxin from Clostridium perfringens

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Protease-nicked theta-toxin of Clostridium perfringens, a new membrane probe with no cytolytic effect, reveals two classes of cholesterol as toxin-binding sites on sheep erythrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

A cytolysin, theta-toxin, preferentially binds to membrane cholesterol surrounded by phospholipids with 18-carbon hydrocarbon chains in cholesterol-rich region

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Effect of lipidic factors on membrane cholesterol topology--mode of binding of theta-toxin to cholesterol in liposomes

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

The projection structure of perfringolysin O (Clostridium perfringens theta-toxin)

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Kinetics of streptolysin O self-assembly

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Membrane-penetrating domain of streptolysin O identified by cysteine scanning mutagenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Assembly mechanism of the oligomeric streptolysin O pore: the early membrane lesion is lined by a free edge of the lipid membrane and is extended gradually during oligomerization

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Streptolysin O: a proposed model of allosteric interaction between a pore-forming protein and its target lipid bilayer

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Interaction of streptolysin O with sterols

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

PEST sequences and regulation by proteolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Structure of a cholesterol-binding, thiol-activated cytolysin and a model of its membrane form

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Evidence for membrane cholesterol as the common binding site for cereolysin, streptolysin O and saponin.

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

The Mechanism of Membrane Insertion for a Cholesterol-Dependent Cytolysin

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Identification of a Membrane-Spanning Domain of the Thiol-Activated Pore-Forming ToxinClostridium perfringensPerfringolysin O: An α-Helical to β-Sheet Transition Identified by Fluorescence Spectroscopy†

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

The mechanism of pore assembly for a cholesterol-dependent cytolysin: formation of a large prepore complex precedes the insertion of the transmembrane beta-hairpins

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

C-terminal amino acid residues are required for the folding and cholesterol binding property of perfringolysin O, a pore-forming cytolysin

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Transmembrane beta-barrel of staphylococcal alpha-toxin forms in sensitive but not in resistant cells

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Oligomerization of the channel-forming toxin aerolysin precedes insertion into lipid bilayers.

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Delivery of proteins into living cells by reversible membrane permeabilization with streptolysin-O

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Pore-forming toxins trigger shedding of receptors for interleukin 6 and lipopolysaccharide.

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Sterol structural requirements for inhibition of streptolysin O activity

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Streptolysin O: the C-terminal, tryptophan-rich domain carries functional sites for both membrane binding and self-interaction but not for stable oligomerization

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Coupling of cholesterol and cone-shaped lipids in bilayers augments membrane permeabilization by the cholesterol-specific toxins streptolysin O and Vibrio cholerae cytolysin

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Effect of defined point mutations in the pneumolysin gene on the virulence of Streptococcus pneumoniae

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Comparative virulence of Streptococcus pneumoniae strains with insertion-duplication, point, and deletion mutations in the pneumolysin gene

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Pneumolysin, a protein toxin of Streptococcus pneumoniae, induces nitric oxide production from macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Cytotoxic Effects In Vitro of Highly Purified Streptolysin O on Mouse Macrophages Cultured in a Serum-Free Medium

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Purification, characterization, and toxicity of the sulfhydryl-activated hemolysin listeriolysin O from Listeria monocytogenes

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Pneumolysin, the thiol-activated toxin of Streptococcus pneumoniae, does not require a thiol group for in vitro activity

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Binding, oligomerization, and pore formation by streptolysin O in erythrocytes and fibroblast membranes: detection of nonlytic polymers

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

Molecular cloning, characterization, and complete nucleotide sequence of the gene for pneumolysin, the sulfhydryl-activated toxin of Streptococcus pneumoniae

1 reference

https://api.crossref.org/works/10.1016%2FS0041-0101%2801%2900155-6

7 January 2021

10.1016/S0041-0101(01)00155-6

Identifiers

DOI

1 reference

1 August 2017

1 reference

PubMed ID

11595631