Glial expression of tumor necrosis factor in transgenic animals: how do these models reflect the "normal situation"? (Q34398665)

1 August 2017

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title

Glial expression of tumor necrosis factor in transgenic animals: how do these models reflect the "normal situation"? (English)

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1 August 2017

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2

Akassoglou K

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1 August 2017

Probert L

1

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PubMed ID

11596129

1 August 2017

language of work or name

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1 November 2001

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1 August 2017

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1 August 2017

36

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1 August 2017

2

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1 August 2017

212-219

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Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice: models for multiple sclerosis with primary oligodendrogliopathy.

1 August 2017

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Impairment of TNF-receptor-1 signaling but not fas signaling diminishes T-cell apoptosis in myelin oligodendrocyte glycoprotein peptide-induced chronic demyelinating autoimmune encephalomyelitis in mice

21 January 2018

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An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

21 January 2018

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Chronic tumor necrosis factor alters T cell responses by attenuating T cell receptor signaling

21 January 2018

1 reference

A critical role of the p75 tumor necrosis factor receptor (p75TNF-R) in organ inflammation independent of TNF, lymphotoxin alpha, or the p55TNF-R.

21 January 2018

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Repeated therapy with monoclonal antibody to tumour necrosis factor alpha (cA2) in patients with rheumatoid arthritis

21 January 2018

1 reference

Tumor necrosis factor-alpha is required in the protective immune response against Mycobacterium tuberculosis in mice

21 January 2018

1 reference

Tumor necrosis factor alpha and lymphotoxin alpha are not required for induction of acute experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

Danger signals: SOS to the immune system

21 January 2018

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The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor

21 January 2018

1 reference

Local expression of transgene encoded TNF alpha in islets prevents autoimmune diabetes in nonobese diabetic (NOD) mice by preventing the development of auto-reactive islet-specific T cells

21 January 2018

1 reference

Tumor necrosis factor identified in multiple sclerosis brain

21 January 2018

1 reference

Prevention of diabetes in nonobese diabetic mice by tumor necrosis factor (TNF): similarities between TNF-alpha and interleukin 1.

21 January 2018

1 reference

Uncoupling the proinflammatory from the immunosuppressive properties of tumor necrosis factor (TNF) at the p55 TNF receptor level: implications for pathogenesis and therapy of autoimmune demyelination

21 January 2018

1 reference

Critical points of tumor necrosis factor action in central nervous system autoimmune inflammation defined by gene targeting

21 January 2018

1 reference

The -308 tumor necrosis factor-alpha promoter polymorphism effects transcription.

21 January 2018

1 reference

TNF is a potent anti-inflammatory cytokine in autoimmune-mediated demyelination.

21 January 2018

1 reference

Crucial role of tumor necrosis factor (TNF) receptor 2 and membrane-bound TNF in experimental cerebral malaria.

21 January 2018

1 reference

Distinct patterns of multiple sclerosis pathology indicates heterogeneity on pathogenesis

21 January 2018

1 reference

A quantitative analysis of oligodendrocytes in multiple sclerosis lesions. A study of 113 cases

21 January 2018

1 reference

Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination

21 January 2018

1 reference

Characterization of tumor necrosis factor-deficient mice

21 January 2018

1 reference

Variation in the TNF-alpha promoter region associated with susceptibility to cerebral malaria.

21 January 2018

1 reference

Cytokines in inflammatory brain lesions: helpful and harmful

21 January 2018

1 reference

Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune re

21 January 2018

1 reference

Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor alpha

21 January 2018

1 reference

An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis

21 January 2018

1 reference

Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions

21 January 2018

1 reference

Association between Tumor Necrosis Factor-α and Disease Progression in Patients with Multiple Sclerosis

21 January 2018

1 reference

Innate immunity and autoimmunity: from self-protection to self-destruction

21 January 2018

1 reference

Late-onset chronic inflammatory encephalopathy in immune-competent and severe combined immune-deficient (SCID) mice with astrocyte-targeted expression of tumor necrosis factor

21 January 2018

1 reference

A critical role for lymphotoxin in experimental allergic encephalomyelitis

21 January 2018

1 reference

The roles of Fas/APO-1 (CD95) and TNF in antigen-induced programmed cell death in T cell receptor transgenic mice.

21 January 2018

1 reference

The two different receptors for tumor necrosis factor mediate distinct cellular responses

21 January 2018

1 reference

A novel domain within the 55 kd TNF receptor signals cell death

21 January 2018

1 reference

The pathophysiology of tumor necrosis factors

21 January 2018

1 reference

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

21 January 2018

1 reference

Two tumour necrosis factor receptors: structure and function.

21 January 2018

1 reference

Treatment of Crohn's disease with anti-tumor necrosis factor chimeric monoclonal antibody (cA2).

21 January 2018

1 reference

Cell death induction by receptors of the TNF family: towards a molecular understanding.

21 January 2018

1 reference

Analysis of gene expression in mutiple sclerosis lesions using cDNA microarrays

21 January 2018

1 reference

Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation

21 January 2018

1 reference

Induction of apoptosis in mature T cells by tumour necrosis factor

21 January 2018

1 reference

Genetic control of multiple sclerosis: increased production of lymphotoxin and tumor necrosis factor-alpha by HLA-DR2+ T cells.

21 January 2018

1 reference

Astrocytes induce blood–brain barrier properties in endothelial cells

21 January 2018

1 reference

Control of established experimental allergic encephalomyelitis by inhibition of tumor necrosis factor (TNF) activity within the central nervous system using monoclonal antibodies and TNF receptor-immunoglobulin fusion proteins

21 January 2018

1 reference

Regulation of autoimmunity by proinflammatory cytokines

21 January 2018

1 reference

Differential expression, cytokine modulation, and specific functions of type-1 and type-2 tumor necrosis factor receptors in rat glia

21 January 2018

1 reference

Severity of symptoms and demyelination in MOG-induced EAE depends on TNFR1

21 January 2018

1 reference

Interferon beta-1b treatment modulates TNFalpha and IFNgamma spontaneous gene expression in MS

21 January 2018

1 reference

Allele-specific quantification of tumor necrosis factor alpha (TNF) transcription and the role of promoter polymorphisms in rheumatoid arthritis patients and healthy individuals

21 January 2018

1 reference

TNF accelerates the onset but does not alter the incidence and severity of myelin basic protein-induced experimental autoimmune encephalomyelitis

21 January 2018

1 reference

A tumor necrosis factor-induced model of human primary demyelinating diseases develops in immunodeficient mice

21 January 2018

1 reference

Tumor necrosis factor blockade in actively induced experimental autoimmune encephalomyelitis prevents clinical disease despite activated T cell infiltration to the central nervous system

21 January 2018

1 reference

Remyelination in multiple sclerosis

21 January 2018

1 reference

Immunological tolerance to a pancreatic antigen as a result of local expression of TNFalpha by islet beta cells

21 January 2018

1 reference

Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro

21 January 2018

1 reference

Prevention of chronic relapsing experimental autoimmune encephalomyelitis by soluble tumor necrosis factor receptor I

21 January 2018

1 reference

Increased severity of experimental autoimmune encephalomyelitis, chronic macrophage/microglial reactivity, and demyelination in transgenic mice producing tumor necrosis factor-alpha in the central nervous system

21 January 2018

1 reference

Transgenic models of TNF induced demyelination

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Differential susceptibility of human CNS-derived cell populations to TNF-dependent and independent immune-mediated injury.

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1002/GLIA.1110

1 reference

1 August 2017

1 reference

PubMed ID

11596129