Ca2+-dependent desensitization of TRPV2 channels is mediated by hydrolysis of phosphatidylinositol 4,5-bisphosphate (Q34401757)

1 August 2017

title

Ca2+-dependent desensitization of TRPV2 channels is mediated by hydrolysis of phosphatidylinositol 4,5-bisphosphate (English)

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1 August 2017

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Jose Mercado

1

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1 August 2017

Ariela Gordon-Shaag

series ordinal

2

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1 August 2017

William N Zagotta

series ordinal

3

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1 August 2017

Sharona E Gordon

series ordinal

4

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1 August 2017

language of work or name

English

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publication date

1 October 2010

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1 August 2017

published in

Journal of Neuroscience

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1 August 2017

volume

30

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1 August 2017

issue

40

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1 August 2017

page(s)

13338-13347

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TRPV2 has a pivotal role in macrophage particle binding and phagocytosis

1 August 2017

cites work

1 reference

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6 July 2018

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6 July 2018

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6 July 2018

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Transient receptor potential channels meet phosphoinositides

6 July 2018

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Determinants of molecular specificity in phosphoinositide regulation. Phosphatidylinositol (4,5)-bisphosphate (PI(4,5)P2) is the endogenous lipid regulating TRPV1.

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Homo- and heteromeric assembly of TRPV channel subunits.

6 July 2018

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A TRPV2-PKA signaling module for transduction of physical stimuli in mast cells

6 July 2018

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2-aminoethoxydiphenyl borate is a common activator of TRPV1, TRPV2, and TRPV3

6 July 2018

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6 July 2018

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Desensitization of Capsaicin-activated Currents in the Vanilloid Receptor TRPV1 Is Decreased by the Cyclic AMP-dependent Protein Kinase Pathway

6 July 2018

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Structural determinant of TRPV1 desensitization interacts with calmodulin

6 July 2018

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Sorting out MIC, TRP, and CRAC ion channels.

6 July 2018

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Calmodulin regulates Ca(2+)-dependent feedback inhibition of store-operated Ca(2+) influx by interaction with a site in the C terminus of TrpC1.

6 July 2018

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The TRPM7 channel is inactivated by PIP(2) hydrolysis

6 July 2018

1 reference

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The transient receptor potential, TRP4, cation channel is a novel member of the family of calmodulin binding proteins

6 July 2018

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Identification of common binding sites for calmodulin and inositol 1,4,5-trisphosphate receptors on the carboxyl termini of trp channels

6 July 2018

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Competitive regulation of CaT-like-mediated Ca2+ entry by protein kinase C and calmodulin

6 July 2018

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Activation of Trp3 by inositol 1,4,5-trisphosphate receptors through displacement of inhibitory calmodulin from a common binding domain.

6 July 2018

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Translocation of a calcium-permeable cation channel induced by insulin-like growth factor-I

6 July 2018

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Vanilloid (Capsaicin) receptors and mechanisms

6 July 2018

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A capsaicin-receptor homologue with a high threshold for noxious heat

6 July 2018

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Visualization of phosphoinositides that bind pleckstrin homology domains: calcium- and agonist-induced dynamic changes and relationship to myo-[3H]inositol-labeled phosphoinositide pools

6 July 2018

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Calmodulin regulation of Drosophila light-activated channels and receptor function mediates termination of the light response in vivo

6 July 2018

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Binding of small basic peptides to membranes containing acidic lipids: theoretical models and experimental results

6 July 2018

1 reference

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Binding of neomycin to phosphatidylinositol 4,5-bisphosphate (PIP2).

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001133

Modulation of the transient receptor potential channel TRPA1 by phosphatidylinositol 4,5-biphosphate manipulators

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001133

Phosphatidylinositol 4,5-bisphosphate rescues TRPM4 channels from desensitization.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001133

PI(4,5)P2 regulates the activation and desensitization of TRPM8 channels through the TRP domain

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001133

Activation of protein kinase C reverses capsaicin-induced calcium-dependent desensitization of TRPV1 ion channels

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001133

Ca2+/calmodulin modulates TRPV1 activation by capsaicin.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001133

TRPV2 Is a Component of Osmotically Sensitive Cation Channels in Murine Aortic Myocytes

27 October 2018

1 reference

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A modular PIP2 binding site as a determinant of capsaicin receptor sensitivity

27 October 2018

1 reference

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cAMP-dependent protein kinase regulates desensitization of the capsaicin receptor (VR1) by direct phosphorylation

27 October 2018

1 reference

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Recovery from muscarinic modulation of M current channels requires phosphatidylinositol 4,5-bisphosphate synthesis

27 October 2018

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Calcium Channels Formed by Mammalian Trp Homologues

27 October 2018

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Intracellular ATP increases capsaicin-activated channel activity by interacting with nucleotide-binding domains.

27 October 2018

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Identification and characterization of two distinct calmodulin-binding sites in the Trpl ion-channel protein of Drosophila melanogaster

27 October 2018

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Structure of the N-terminal Ankyrin Repeat Domain of the TRPV2 Ion Channel

27 October 2018

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Inhibition of calmodulin-activated smooth-muscle myosin light-chain kinase by calmodulin-binding peptides and fluorescent (phosphodiesterase-activating) calmodulin derivatives

9 December 2018

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12 December 2020

Inhibition of calcineurin inhibits the desensitization of capsaicin-evoked currents in cultured dorsal root ganglion neurones from adult rats

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12 December 2020

Adsorption of cations to phosphatidylinositol 4,5-bisphosphate

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The role of calcium in the desensitization of capsaicin responses in rat dorsal root ganglion neurons

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Neurochemical characteristics of a novel dorsal root ganglion X neuroblastoma hybrid cell line, F-11

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10.1523/JNEUROSCI.2108-10.2010

Identifiers

DOI

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1 August 2017

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1 August 2017

1 reference