Polymorphisms in endothelial nitric oxide synthase (eNOS) and vascular endothelial growth factor (VEGF) predict sunitinib-induced hypertension (Q34403301)

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English	Polymorphisms in endothelial nitric oxide synthase (eNOS) and vascular endothelial growth factor (VEGF) predict sunitinib-induced hypertension	scientific article

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scholarly article

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1 August 2017

Polymorphisms in endothelial nitric oxide synthase (eNOS) and vascular endothelial growth factor (VEGF) predict sunitinib-induced hypertension (English)

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Europe PubMed Central

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1 August 2017

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arterial hypertension

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Henk-Jan Guchelaar

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author name string

K Eechoute

1

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1 August 2017

A A M van der Veldt

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1 August 2017

S Oosting

3

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1 August 2017

M H W Kappers

4

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1 August 2017

J A M Wessels

5

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1 August 2017

H Gelderblom

6

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1 August 2017

H-J Guchelaar

7

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1 August 2017

A K L Reyners

8

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1 August 2017

C M L van Herpen

9

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1 August 2017

J B Haanen

10

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1 August 2017

R H J Mathijssen

11

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1 August 2017

E Boven

12

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1 August 2017

language of work or name

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publication date

5 September 2012

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1 August 2017

Clinical Pharmacology & Therapeutics

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1 August 2017

92

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1 August 2017

4

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1 August 2017

503-510

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1 August 2017

Sunitinib: from rational design to clinical efficacy

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https://api.crossref.org/works/10.1038%2FCLPT.2012.136

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The biology of VEGF and its receptors

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Hallmarks of Cancer: The Next Generation

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Molecular mechanisms and clinical applications of angiogenesis

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https://api.crossref.org/works/10.1038%2FCLPT.2012.136

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Activity of sunitinib in patients with advanced neuroendocrine tumors

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https://api.crossref.org/works/10.1038%2FCLPT.2012.136

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Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial

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Sunitinib versus interferon alfa in metastatic renal-cell carcinoma

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Sunitinib malate for the treatment of pancreatic neuroendocrine tumors

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Sunitinib in urothelial cancer: clinical, pharmacokinetic, and immunohistochemical study of predictors of response.

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https://api.crossref.org/works/10.1038%2FCLPT.2012.136

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Hypertension as a biomarker of efficacy in patients with metastatic renal cell carcinoma treated with sunitinib

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https://api.crossref.org/works/10.1038%2FCLPT.2012.136

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Arterial hypertension and clinical benefit of sunitinib, sorafenib and bevacizumab in first and second-line treatment of metastatic renal cell cancer.

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https://api.crossref.org/works/10.1038%2FCLPT.2012.136

21 January 2018

Physiological antagonism of endothelin-1 in human conductance and resistance coronary artery

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https://api.crossref.org/works/10.1038%2FCLPT.2012.136

21 January 2018

Hypertension Induced by the Tyrosine Kinase Inhibitor Sunitinib Is Associated With Increased Circulating Endothelin-1 Levels

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.136

21 January 2018

Effective strategies for management of hypertension after vascular endothelial growth factor signaling inhibition therapy: results from a phase II randomized, factorial, double-blind study of Cediranib in patients with advanced solid tumors

1 reference

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21 January 2018

Pharmacogenetic pathway analysis for determination of sunitinib-induced toxicity

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https://api.crossref.org/works/10.1038%2FCLPT.2012.136

21 January 2018

Hypertension and rarefaction during treatment with telatinib, a small molecule angiogenesis inhibitor

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https://api.crossref.org/works/10.1038%2FCLPT.2012.136

21 January 2018

Reduction in skin microvascular density and changes in vessel morphology in patients treated with sunitinib

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.136

21 January 2018

Sunitinib induced hypertension, thrombotic microangiopathy and reversible posterior leukencephalopathy syndrome.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.136

21 January 2018

Reversible posterior leucoencephalopathy syndrome in an elderly male on sunitinib therapy

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https://api.crossref.org/works/10.1038%2FCLPT.2012.136

21 January 2018

VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.136

21 January 2018

Vascular endothelial growth factor genetic variability and coronary artery disease in Brazilian population.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.136

21 January 2018

VEGF polymorphisms and severity of atherosclerosis.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.136

21 January 2018

Replication protein A1 reduces transcription of the endothelial nitric oxide synthase gene containing a -786T-->C mutation associated with coronary spastic angina.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.136

21 January 2018

Endothelial nitric oxide synthase gene haplotypes affect nitrite levels in black subjects

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.136

21 January 2018

T-786-->C mutation in the 5'-flanking region of the endothelial nitric oxide synthase gene is associated with coronary spasm

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.136

21 January 2018

The outcome and predictive factors of sunitinib therapy in advanced gastrointestinal stromal tumors (GIST) after imatinib failure - one institution study

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.136

21 January 2018

VEGF pathway genetic variants as biomarkers of treatment outcome with bevacizumab: an analysis of data from the AViTA and AVOREN randomised trials

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.136

21 January 2018

Association of VEGF and VEGFR2 single nucleotide polymorphisms with hypertension and clinical outcome in metastatic clear cell renal cell carcinoma patients treated with sunitinib

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.136

21 January 2018

Genetic and pharmacogenetic associations between NOS3 polymorphisms, blood pressure, and cardiovascular events in hypertension

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.136

21 January 2018

Association between -T786C NOS3 polymorphism and resistant hypertension: a prospective cohort study

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.136

21 January 2018

The role of genetics in susceptibility to diabetic retinopathy

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.136

21 January 2018

Investigating the association between K198N coding polymorphism in EDN1 and hypertension, lipoprotein levels, the metabolic syndrome and cardiovascular disease.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.136

21 January 2018

Hypertension as a predictive factor for survival outcomes in patients with metastatic renal cell carcinoma treated with sunitinib after progression on cytokines

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.136

7 January 2021

based on heuristic

inferred from DOI database lookup

Diastolic blood pressure as a biomarker of axitinib efficacy in solid tumors

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.136

7 January 2021

based on heuristic

inferred from DOI database lookup

Hypertension as predictor of sunitinib treatment outcome in metastatic renal cell carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.136

7 January 2021

based on heuristic

inferred from DOI database lookup

NO and prostanoids blunt endothelin-mediated coronary vasoconstrictor influence in exercising swine

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.136

7 January 2021

based on heuristic

inferred from DOI database lookup

The vascular endothelial growth factor receptor inhibitor sunitinib causes a preeclampsia-like syndrome with activation of the endothelin system

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.136

7 January 2021

based on heuristic

inferred from DOI database lookup

The relationship of VEGF polymorphisms with serum VEGF levels and progression-free survival in patients with epithelial ovarian cancer

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.136

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA sequence variation in the promoter region of the VEGF gene impacts VEGF gene expression and maximal oxygen consumption

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.136

7 January 2021

based on heuristic

inferred from DOI database lookup

Interaction between smoking and polymorphism in the promoter region of the VEGFA gene is associated with ischemic heart disease and myocardial infarction in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.136

7 January 2021

based on heuristic

inferred from DOI database lookup

Modulation of nitric oxide formation by endothelial nitric oxide synthase gene haplotypes

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.136

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence of association of the ecNOS gene polymorphism with plasma NO metabolite levels in humans

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.136

7 January 2021

based on heuristic

inferred from DOI database lookup

eNOS haplotypes associated with gestational hypertension or preeclampsia

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.136

7 January 2021

based on heuristic

inferred from DOI database lookup

Single nucleotide polymorphism associations with response and toxic effects in patients with advanced renal-cell carcinoma treated with first-line sunitinib: a multicentre, observational, prospective study

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.136

7 January 2021

based on heuristic

inferred from DOI database lookup

Vascular endothelial growth factor polymorphisms and extent of coronary atherosclerosis in Chinese population with advanced coronary artery disease

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.136

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic polymorphisms associated with a prolonged progression-free survival in patients with metastatic renal cell cancer treated with sunitinib

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.136

7 January 2021

based on heuristic

inferred from DOI database lookup

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10.1038/CLPT.2012.136

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

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