Molecular heterogeneity of the XbaI defined 44kb allele of the CYP2D locus within the Caucasian population (Q34403562)

1 August 2017

title

Molecular heterogeneity of the XbaI defined 44kb allele of the CYP2D locus within the Caucasian population (English)

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1 August 2017

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Mura C

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1 August 2017

Gerard N

2

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1 August 2017

Vincent-Viry M

3

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1 August 2017

Galteau MM

4

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1 August 2017

Jacqz-Aigrain E

5

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1 August 2017

Krishnamoorthy R

6

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1 August 2017

language of work or name

English

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publication date

1 February 1993

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British Journal of Clinical Pharmacology

1 August 2017

published in

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1 August 2017

volume

35

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1 August 2017

issue

2

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1 August 2017

page(s)

161-165

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A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population.

1 August 2017

cites work

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Genetically determined oxidation capacity and the disposition of debrisoquine

6 July 2018

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P450 genes: structure, evolution, and regulation

6 July 2018

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Two mutant alleles of the human cytochrome P-450db1 gene (P450C2D1) associated with genetically deficient metabolism of debrisoquine and other drugs

6 July 2018

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The human debrisoquine 4-hydroxylase (CYP2D) locus: sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene

6 July 2018

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Multiple mutations of the human cytochrome P450IID6 gene (CYP2D6) in poor metabolizers of debrisoquine. Study of the functional significance of individual mutations by expression of chimeric genes

6 July 2018

1 reference

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The genetic polymorphism of debrisoquine/sparteine metabolism--clinical aspects

6 July 2018

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Recent developments in hepatic drug oxidation. Implications for clinical pharmacokinetics

6 July 2018

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The genetic polymorphism of debrisoquine/sparteine metabolism-molecular mechanisms

6 July 2018

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The human CYP2D locus associated with a common genetic defect in drug oxidation: a G1934----A base change in intron 3 of a mutant CYP2D6 allele results in an aberrant 3' splice recognition site

6 July 2018

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Identification of the primary gene defect at the cytochrome P450 CYP2D locus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381508

Distinct phenotypes and genotypes of debrisoquine hydroxylation among Europeans and Chinese

6 July 2018

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Phenotypic debrisoquine 4-hydroxylase activity among extensive metabolizers is unrelated to genotype as determined by the Xba-I restriction fragment length polymorphism

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381508

Debrisoquine/sparteine hydroxylation genotype and phenotype: analysis of common mutations and alleles of CYP2D6 in a European population

6 July 2018

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Molecular genetics of the debrisoquin-sparteine polymorphism

6 July 2018

1 reference

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Deletion of the entire cytochrome P450 CYP2D6 gene as a cause of impaired drug metabolism in poor metabolizers of the debrisoquine/sparteine polymorphism

6 July 2018

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Polymorphic hydroxylation of Debrisoquine in man.

6 July 2018

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Direct determination of dextromethorphan and its three metabolites in urine by high-performance liquid chromatography using a precolumn switching system for sample clean-up

6 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1993.TB05681.X

Analysis of the CYP2D6 gene in relation to debrisoquin and desipramine hydroxylation in a Swedish population

21 January 2018

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12 December 2020

Phenotyping polymorphic drug metabolism in the French Caucasian population

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12 December 2020

Clinical significance of the sparteine/debrisoquine oxidation polymorphism

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12 December 2020

Xbal 16- plus 9-kilobase DNA restriction fragments identify a mutant allele for debrisoquin hydroxylase: report of a family study

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12 December 2020

Molecular genotyping to predict debrisoquine hydroxylation phenotype

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12 December 2020

Detection of debrisoquine hydroxylation phenotypes

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12 December 2020

Hydroxylation polymorphisms of debrisoquine and mephenytoin in European populations

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12 December 2020

Genetic analysis of the interethnic difference between Chinese and Caucasians in the polymorphic metabolism of debrisoquine and codeine

1 reference

12 December 2020

10.1111/J.1365-2125.1993.TB05681.X

Identifiers

DOI

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1 August 2017

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1 August 2017

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