HLXB9 activates IL6 in Hodgkin lymphoma cell lines and is regulated by PI3K signalling involving E2F3. (Q34403841)

1 August 2017

title

HLXB9 activates IL6 in Hodgkin lymphoma cell lines and is regulated by PI3K signalling involving E2F3. (English)

1 reference

1 August 2017

1 reference

6

Drexler HG

1 reference

1 August 2017

3

Quentmeier H

1 reference

1 August 2017

Nagel S

1

1 reference

1 August 2017

Scherr M

2

1 reference

1 August 2017

Kaufmann M

4

1 reference

1 August 2017

Zaborski M

5

1 reference

1 August 2017

MacLeod RA

7

1 reference

1 August 2017

publication date

1 May 2005

1 reference

1 August 2017

1 reference

1 August 2017

volume

19

1 reference

1 August 2017

issue

5

1 reference

1 August 2017

page(s)

841-846

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.leu.2403716

1 August 2017

exact match

0 references

cites work

IL-6 levels and genotype are associated with risk of young adult Hodgkin lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

Constitutive NF-kappaB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

A multiple cytokine- and second messenger-responsive element in the enhancer of the human interleukin-6 gene: similarities with c-fos gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

Activation of interleukin-6 gene expression through the NF-kappa B transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

Epstein-Barr virus-encoded LMP1 and CD40 mediate IL-6 production in epithelial cells via an NF-kappaB pathway involving TNF receptor-associated factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

STAT3 is constitutively activated in Hodgkin cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

MEK/ERK pathway is aberrantly active in Hodgkin disease: a signaling pathway shared by CD30, CD40, and RANK that regulates cell proliferation and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

Coexpression of BMI-1 and EZH2 polycomb group genes in Reed-Sternberg cells of Hodgkin's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

Unique polycomb gene expression pattern in Hodgkin's lymphoma and Hodgkin's lymphoma-derived cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

Abnormal PcG protein expression in Hodgkin's lymphoma. Relation with E2F6 and NFkappaB transcription factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

HOX and non-HOX homeobox genes in leukemic hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

Beyond the Hox: how widespread is homeobox gene clustering?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

Activation of HOX11L2 by juxtaposition with 3'-BCL11B in an acute lymphoblastic leukemia cell line (HPB-ALL) with t(5;14)(q35;q32.2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

A homeobox gene, HLXB9, is the major locus for dominantly inherited sacral agenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

Activation of HLXB9 by juxtaposition with MYB via formation of t(6;7)(q23;q36) in an AML-M4 cell line (GDM-1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

CD30 triggering by agonistic antibodies regulates CXCR4 expression and CXCL12 chemotactic activity in the cell line L540.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

The homeobox gene GBX2, a target of the myb oncogene, mediates autocrine growth and monocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

Analysis of embryonic motoneuron gene regulation: derepression of general activators function in concert with enhancer factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

Differential signaling pathways are activated in the Epstein-Barr virus-associated malignancies nasopharyngeal carcinoma and Hodgkin lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

c-Myb transcription is activated by protein kinase B (PKB) following interleukin 2 stimulation of Tcells and is required for PKB-mediated protection from apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

Amplification and overexpression of E2F3 in human bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

p70(s6k) integrates phosphatidylinositol 3-kinase and rapamycin-regulated signals for E2F regulation in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

Specificity in the activation and control of transcription factor E2F-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

Role of PI3K/AKT/mTOR signaling in the cell cycle progression of human prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

Identification of a novel E2F3 product suggests a mechanism for determining specificity of repression by Rb proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

E2F target genes: unraveling the biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

Identification of genes periodically expressed in the human cell cycle and their expression in tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

E2F3 activity is regulated during the cell cycle and is required for the induction of S phase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

RYBP, a new repressor protein that interacts with components of the mammalian Polycomb complex, and with the transcription factor YY1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

Interaction of YY1 with E2Fs, mediated by RYBP, provides a mechanism for specificity of E2F function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

Hodgkin and Reed-Sternberg cells harbor alterations in the major tumor suppressor pathways and cell-cycle checkpoints: analyses using tissue microarrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

Soluble cytokine levels correlate with the activity and clinical stage of Hodgkin's disease at diagnosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

7 January 2021

Interleukin 6 expression by Hodgkin/Reed-Sternberg cells is associated with the presence of 'B' symptoms and failure to achieve complete remission in patients with advanced Hodgkin's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

7 January 2021

High-throughput tissue microarray analysis of G1-cyclin alterations in classical Hodgkin's lymphoma indicates overexpression of cyclin E1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

7 January 2021

The homeodomain transcription factors Islet 1 and HB9 are expressed in adult alpha and gamma motoneurons identified by selective retrograde tracing

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

7 January 2021

Pancreas dorsal lobe agenesis and abnormal islets of Langerhans in Hlxb9-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

7 January 2021

Monitoring of BCR-ABL expression using real-time RT-PCR in CML after bone marrow or peripheral blood stem cell transplantation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403716

7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2403716

1 reference

Dimensions Publication ID

1 August 2017

1047278129

0 references

1 reference