A new tumour suppression mechanism by p27Kip1: EGFR down-regulation mediated by JNK/c-Jun pathway inhibition. (Q34406424)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25121353%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

title

A new tumour suppression mechanism by p27Kip1: EGFR down-regulation mediated by JNK/c-Jun pathway inhibition (English)

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12 March 2020

10

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12 March 2020

Chuanshu Huang

11

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12 March 2020

author name string

Yong Fang

1

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12 March 2020

Yihong Wang

2

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12 March 2020

Yulei Wang

3

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12 March 2020

Yan Meng

4

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12 March 2020

Junlan Zhu

5

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12 March 2020

Honglei Jin

6

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12 March 2020

Jingxia Li

7

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12 March 2020

Dongyun Zhang

8

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12 March 2020

Yonghui Yu

9

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12 March 2020

language of work or name

English

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publication date

1 November 2014

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12 March 2020

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12 March 2020

volume

463

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12 March 2020

issue

3

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12 March 2020

page(s)

383-392

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Creative Commons Attribution 3.0 Unported

12 March 2020

copyright license

start time

25 July 2019

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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Novel mechanism of reduced proliferation in ovarian clear cell carcinoma cells: cytoplasmic sequestration of CDK2 by p27.

6 July 2018

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Dual blockade of EGFR and c-Met abrogates redundant signaling and proliferation in head and neck carcinoma cells

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Silencing kinase-interacting stathmin gene enhances erlotinib sensitivity by inhibiting Ser¹⁰ p27 phosphorylation in epidermal growth factor receptor-expressing breast cancer

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p27 suppresses arsenite-induced Hsp27/Hsp70 expression through inhibiting JNK2/c-Jun- and HSF-1-dependent pathways

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TM4SF5 accelerates G1/S phase progression via cytosolic p27Kip1 expression and RhoA activity

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6 July 2018

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c-Jun/AP-1 pathway-mediated cyclin D1 expression participates in low dose arsenite-induced transformation in mouse epidermal JB6 Cl41 cells

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Targeting the p27 E3 ligase SCF(Skp2) results in p27- and Skp2-mediated cell-cycle arrest and activation of autophagy

6 July 2018

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c-jun-NH2JNK mediates invasive potential and EGFR activation by regulating the expression of HB-EGF in a urokinase-stimulated pathway

6 July 2018

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Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation

6 July 2018

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Testing the importance of p27 degradation by the SCFskp2 pathway in murine models of lung and colon cancer.

6 July 2018

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Neuromedin U is regulated by the metastasis suppressor RhoGDI2 and is a novel promoter of tumor formation, lung metastasis and cancer cachexia

6 July 2018

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p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion

6 July 2018

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JNK activation is required for JB6 cell transformation induced by tumor necrosis factor-alpha but not by 12-O-tetradecanoylphorbol-13-acetate

6 July 2018

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Arsenic induces apoptosis through a c-Jun NH2-terminal kinase-dependent, p53-independent pathway.

6 July 2018

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Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

6 July 2018

1 reference

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Cytoplasmic p27 expression is an independent prognostic factor in ovarian cancer.

6 July 2018

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Attenuated expression of menin and p27 (Kip1) in an aggressive case of multiple endocrine neoplasia type 1 (MEN1) associated with an atypical prolactinoma and a malignant pancreatic endocrine tumor.

21 January 2018

1 reference

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Cyclin D1 induction through IkappaB kinase beta/nuclear factor-kappaB pathway is responsible for arsenite-induced increased cell cycle G1-S phase transition in human keratinocytes

21 January 2018

1 reference

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Large-scale analysis of cell cycle regulators in urothelial bladder cancer identifies p16 and p27 as potentially useful prognostic markers.

21 January 2018

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Cdk2 is dispensable for cell cycle inhibition and tumor suppression mediated by p27(Kip1) and p21(Cip1).

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20140103

Combined loss of p21(waf1/cip1) and p27(kip1) enhances tumorigenesis in mice.

21 January 2018

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PAkt, cyclin D1 and p27/Kip.1 in glioblastomas with and without EGFR amplification and PTEN mutation.

21 January 2018

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Reduced expression of p27(Kip1) correlates with an early stage of cancer invasion in oral squamous cell carcinoma

27 October 2018

1 reference

12 December 2020

p27/Kip1 mutation found in breast cancer

1 reference

12 December 2020

p27: tumor suppressor and oncogene ...?

1 reference

12 December 2020

Constitutive activation of c-Jun N-terminal kinase correlates with histologic grade and EGFR expression in diffuse gliomas

1 reference

12 December 2020

Normal intestinal epithelial cell differentiation in the absence of p21 and p27: new insights from old knock-out mice

1 reference

12 December 2020

Identifiers

DOI

10.1042/BJ20140103

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25121353%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25121353%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25121353%20AND%20SRC:MED&resulttype=core&format=json