The nuclear localization sequences of the BRCA1 protein interact with the importin-alpha subunit of the nuclear transport signal receptor (Q34410413)

2 August 2017

title

The nuclear localization sequences of the BRCA1 protein interact with the importin-alpha subunit of the nuclear transport signal receptor (English)

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2 August 2017

Chen CF

1

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2 August 2017

Li S

2

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2 August 2017

Chen Y

3

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2 August 2017

Chen PL

4

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2 August 2017

Sharp ZD

5

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2 August 2017

Lee WH

6

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2 August 2017

language of work or name

English

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publication date

1 December 1996

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Journal of Biological Chemistry

2 August 2017

published in

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2 August 2017

volume

271

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2 August 2017

issue

51

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2 August 2017

page(s)

32863-32868

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A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

2 August 2017

cites work

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Expression of Brca1 is associated with terminal differentiation of ectodermally and mesodermally derived tissues in mice

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The developmental pattern of Brca1 expression implies a role in differentiation of the breast and other tissues

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Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities

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Inactivation of the mouse Brca1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development.

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The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse

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BRCA1 mutations in primary breast and ovarian carcinomas

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A somatic BRCA1 mutation in an ovarian tumour

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Has the breast cancer gene been found?

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Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion

21 January 2018

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Protein import into the nucleus: an integrated view

21 January 2018

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Nuclear targeting sequences--a consensus?

21 January 2018

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Nuclear import can be separated into distinct steps in vitro: nuclear pore binding and translocation

21 January 2018

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A polypeptide domain that specifies migration of nucleoplasmin into the nucleus

21 January 2018

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A short amino acid sequence able to specify nuclear location

21 January 2018

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Isolation of a protein that is essential for the first step of nuclear protein import

21 January 2018

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Two different subunits of importin cooperate to recognize nuclear localization signals and bind them to the nuclear envelope

21 January 2018

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The GTP-binding protein Ran/TC4 is required for protein import into the nucleus

21 January 2018

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Distinct functions for the two importin subunits in nuclear protein import

21 January 2018

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Aberrant subcellular localization of BRCA1 in breast cancer

21 January 2018

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BRCA1 is secreted and exhibits properties of a granin

21 January 2018

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Identification of hSRP1 alpha as a functional receptor for nuclear localization sequences

21 January 2018

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Identification of a protein complex that is required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins

21 January 2018

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The retinoblastoma gene product is a cell cycle-dependent, nuclear matrix-associated protein

21 January 2018

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The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit

21 January 2018

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Separation of DNA binding from the transcription-activating function of a eukaryotic regulatory protein

21 January 2018

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Deletion analysis of GAL4 defines two transcriptional activating segments

21 January 2018

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Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: identification of a class of bipartite nuclear targeting sequence

21 January 2018

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Nuclear location signals in polyoma virus large-T.

21 January 2018

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Nuclear localization of the adenovirus DNA-binding protein: requirement for two signals and complementation during viral infection

21 January 2018

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BRCA1 protein products: Antibody specificity…

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.271.51.32863

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2 August 2017

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