Deregulated expression of RasGRP1 initiates thymic lymphomagenesis independently of T-cell receptors (Q34411416)

2 August 2017

Deregulated expression of RasGRP1 initiates thymic lymphomagenesis independently of T-cell receptors (English)

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2 August 2017

Mark B Klinger

1

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2 August 2017

Benoit Guilbault

series ordinal

2

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2 August 2017

Rebecca E Goulding

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3

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2 August 2017

Robert J Kay

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4

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2 August 2017

language of work or name

English

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publication date

1 April 2005

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2 August 2017

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2 August 2017

24

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2 August 2017

16

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2 August 2017

2695-2704

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1208334

2 August 2017

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CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity

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Genome-based identification of cancer genes by proviral tagging in mouse retrovirus-induced T-cell lymphomas

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A growing family of guanine nucleotide exchange factors is responsible for activation of ras-family GTPases

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Selection of the T cell repertoire.

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Activated Ras signals differentiation and expansion of CD4+8+ thymocytes

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Premature expression of T cell receptor (TCR)alphabeta suppresses TCRgammadelta gene rearrangement but permits development of gammadelta lineage T cells

21 January 2018

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Transgenic models of lymphoid neoplasia and development of a pan-hematopoietic vector

21 January 2018

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7 January 2021

Analysis of TCR, pT alpha, and RAG-1 in T-acute lymphoblastic leukemias improves understanding of early human T-lymphoid lineage commitment.

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7 January 2021

The alpha beta T cell receptor can replace the gamma delta receptor in the development of gamma delta lineage cells.

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7 January 2021

Loss of Rho function in the thymus is accompanied by the development of thymic lymphoma

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7 January 2021

The CD2-scl transgene alters the phenotype and frequency of T-lymphomas in N-ras transgenic or p53 deficient mice.

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7 January 2021

Distinct signals mediate maturation and allelic exclusion in lymphocyte progenitors

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7 January 2021

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

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7 January 2021

Autoimmunity as the consequence of a spontaneous mutation in Rasgrp1.

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7 January 2021

Isozyme variation in Larrea ameghinoi and Larrea nitida (Zygophyllaceae): genetic diversity and its bearing on their relationship

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208334

7 January 2021

Transgenic expression of RasGRP1 induces the maturation of double-negative thymocytes and enhances the production of CD8 single-positive thymocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208334

7 January 2021

RasGRP1 transduces low-grade TCR signals which are critical for T cell development, homeostasis, and differentiation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208334

7 January 2021

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

1 reference

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7 January 2021

Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1208334

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Dimensions Publication ID

2 August 2017

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