Association of reduced type IX collagen gene expression in human osteoarthritic chondrocytes with epigenetic silencing by DNA hypermethylation (Q34416053)

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English	Association of reduced type IX collagen gene expression in human osteoarthritic chondrocytes with epigenetic silencing by DNA hypermethylation	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 August 2017

Association of reduced type IX collagen gene expression in human osteoarthritic chondrocytes with epigenetic silencing by DNA hypermethylation (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

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hypermethylation

1 reference

based on heuristic

inferred from title

8

object named as

Richard O C Oreffo

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Europe PubMed Central

PubMed publication ID

2 August 2017

Mary B Goldring

7

object named as

Mary B Goldring

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Europe PubMed Central

PubMed publication ID

2 August 2017

author name string

Kei Imagawa

1

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Europe PubMed Central

PubMed publication ID

2 August 2017

María C de Andrés

2

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Europe PubMed Central

PubMed publication ID

2 August 2017

Ko Hashimoto

3

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Eiji Itoi

4

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Miguel Otero

5

1 reference

Europe PubMed Central

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2 August 2017

Helmtrud I Roach

6

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PubMed publication ID

2 August 2017

publication date

1 November 2014

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Europe PubMed Central

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2 August 2017

Arthritis & Rheumatology

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Europe PubMed Central

PubMed publication ID

2 August 2017

66

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Europe PubMed Central

PubMed publication ID

2 August 2017

11

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Europe PubMed Central

PubMed publication ID

2 August 2017

3040-3051

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Europe PubMed Central

PubMed publication ID

2 August 2017

Comparative proteomic analysis of normal and collagen IX null mouse cartilage reveals altered extracellular matrix composition and novel components of the collagen IX interactome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211984

6 July 2018

Regulated transcription of human matrix metalloproteinase 13 (MMP13) and interleukin-1β (IL1B) genes in chondrocytes depends on methylation of specific proximal promoter CpG sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211984

6 July 2018

Loss of methylation in CpG sites in the NF-κB enhancer elements of inducible nitric oxide synthase is responsible for gene induction in human articular chondrocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211984

6 July 2018

Changes in the epigenetic status of the SOX-9 promoter in human osteoarthritic cartilage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211984

6 July 2018

cAMP response element-binding (CREB) recruitment following a specific CpG demethylation leads to the elevated expression of the matrix metalloproteinase 13 in human articular chondrocytes and osteoarthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211984

6 July 2018

Expression of the osteoarthritis-associated gene GDF5 is modulated epigenetically by DNA methylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211984

6 July 2018

The epigenetic effect of glucosamine and a nuclear factor-kappa B (NF-kB) inhibitor on primary human chondrocytes--implications for osteoarthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211984

6 July 2018

Superoxide dismutase downregulation in osteoarthritis progression and end-stage disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211984

6 July 2018

DNA demethylation at specific CpG sites in the IL1B promoter in response to inflammatory cytokines in human articular chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211984

6 July 2018

Methylation of the OP-1 promoter: potential role in the age-related decline in OP-1 expression in cartilage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211984

6 July 2018

Differential expression of GADD45beta in normal and osteoarthritic cartilage: potential role in homeostasis of articular chondrocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211984

6 July 2018

Connections between epigenetic gene silencing and human disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211984

6 July 2018

Articular cartilage collagen: an irreplaceable framework?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211984

6 July 2018

The control of chondrogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211984

6 July 2018

Association between the abnormal expression of matrix-degrading enzymes by human osteoarthritic chondrocytes and demethylation of specific CpG sites in the promoter regions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211984

6 July 2018

Evidence for a role of the genomic region of the gene encoding for the alpha1 chain of type IX collagen (COL9A1) in hip osteoarthritis: A population-based study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211984

6 July 2018

SOX9 expression does not correlate with type II collagen expression in adult articular chondrocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211984

6 July 2018

Regulation of human COL9A1 gene expression. Activation of the proximal promoter region by SOX9

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211984

6 July 2018

Collagen of articular cartilage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211984

6 July 2018

Hypoxia in cartilage: HIF-1alpha is essential for chondrocyte growth arrest and survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211984

6 July 2018

Regulation of human COL2A1 gene expression in chondrocytes. Identification of C-Krox-responsive elements and modulation by phenotype alteration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211984

6 July 2018

A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211984

6 July 2018

SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211984

6 July 2018

Mice lacking alpha 1 (IX) collagen develop noninflammatory degenerative joint disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211984

6 July 2018

Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211984

6 July 2018

Interleukin-1 beta-modulated gene expression in immortalized human chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211984

6 July 2018

A COL2A1 mutation in achondrogenesis type II results in the replacement of type II collagen by type I and III collagens in cartilage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211984

6 July 2018

The effects of 5-azacytidine and 5-azadeoxycytidine on chromosome structure and function: implications for methylation-associated cellular processes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211984

6 July 2018

Methylation in the preinitiation domain suppresses gene transcription by an indirect mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211984

6 July 2018

Correlation of COL10A1 induction during chondrogenesis of mesenchymal stem cells with demethylation of two CpG sites in the COL10A1 promoter.

1 reference

https://api.crossref.org/works/10.1002%2FART.38774

21 January 2018

Cellular and epigenetic features of a young healthy and a young osteoarthritic cartilage compared with aged control and OA cartilage.

1 reference

https://api.crossref.org/works/10.1002%2FART.38774

21 January 2018

Improved quantification of DNA methylation using methylation-sensitive restriction enzymes and real-time PCR.

1 reference

https://api.crossref.org/works/10.1002%2FART.38774

21 January 2018

Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein

1 reference

https://api.crossref.org/works/10.1002%2FART.38774

21 January 2018

Gene expression profiling of dedifferentiated human articular chondrocytes in monolayer culture

1 reference

https://api.crossref.org/works/10.1002%2FART.38774

21 January 2018

DNA methylation is not likely to be responsible for aggrecan down regulation in aged or osteoarthritic cartilage

1 reference

https://api.crossref.org/works/10.1002%2FART.38774

21 January 2018

Suitability of porcine chondrocyte micromass culture to model osteoarthritis in vitro

1 reference

https://api.crossref.org/works/10.1002%2FART.38774

21 January 2018

Genome-wide expression profiling reveals new candidate genes associated with osteoarthritis.

1 reference

https://api.crossref.org/works/10.1002%2FART.38774

21 January 2018

Hypoxia-inducible factor 1alpha inhibits the fibroblast-like markers type I and type III collagen during hypoxia-induced chondrocyte redifferentiation: hypoxia not only induces type II collagen and aggrecan, but it also inhibits type I and type III

1 reference

https://pubmed.ncbi.nlm.nih.gov/25048791

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia-inducible factor-2alpha is a catabolic regulator of osteoarthritic cartilage destruction

1 reference

https://pubmed.ncbi.nlm.nih.gov/25048791

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Linkage analysis of candidate genes as susceptibility loci for osteoarthritis-suggestive linkage of COL9A1 to female hip osteoarthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25048791

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of Sox9 and type IIA procollagen during attempted repair of articular cartilage damage in a transgenic mouse model of osteoarthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25048791

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Finer linkage mapping of a primary hip osteoarthritis susceptibility locus on chromosome 6

1 reference

https://pubmed.ncbi.nlm.nih.gov/25048791

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toward a human epigenome

1 reference

https://pubmed.ncbi.nlm.nih.gov/25048791

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Large-scale gene expression profiling reveals major pathogenetic pathways of cartilage degeneration in osteoarthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25048791

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional analysis of promoter CpG methylation using a CpG-free luciferase reporter vector

1 reference

https://pubmed.ncbi.nlm.nih.gov/25048791

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absence of the alpha1(IX) chain leads to a functional knock-out of the entire collagen IX protein in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/25048791

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SOX trio decrease in the articular cartilage with the advancement of osteoarthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25048791

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the pathogenic pathways in osteoarthritic hip cartilage: commonality and discord between hip and knee OA

1 reference

https://pubmed.ncbi.nlm.nih.gov/25048791

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of ADAMTS-4 by chondrocytes in the surface zone of human osteoarthritic cartilage is regulated by epigenetic DNA de-methylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25048791

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA methylation is not responsible for p21WAF1/CIP1 down-regulation in osteoarthritic chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/25048791

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/ART.38774

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

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