Simultaneous blockade of multiple immune system inhibitory checkpoints enhances antitumor activity mediated by interleukin-15 in a murine metastatic colon carcinoma model (Q34420239)

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English	Simultaneous blockade of multiple immune system inhibitory checkpoints enhances antitumor activity mediated by interleukin-15 in a murine metastatic colon carcinoma model	scientific article

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15 February 2020

Simultaneous blockade of multiple immune system inhibitory checkpoints enhances antitumor activity mediated by interleukin-15 in a murine metastatic colon carcinoma model (English)

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15 February 2020

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colon carcinoma

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inferred from title

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15 February 2020

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Ping Yu

1

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15 February 2020

Meili Zhang

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15 February 2020

John C Morris

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15 February 2020

Thomas A Waldmann

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5 October 2010

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15 February 2020

Clinical Cancer Research

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15 February 2020

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15 February 2020

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15 February 2020

6019-6028

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15 February 2020

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

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6 July 2018

Interleukin-15 and its receptor augment dendritic cell vaccination against the neu oncogene through the induction of antibodies partially independent of CD4 help.

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6 July 2018

Trans-presentation: a novel mechanism regulating IL-15 delivery and responses

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6 July 2018

Interleukin-15 combined with an anti-CD40 antibody provides enhanced therapeutic efficacy for murine models of colon cancer

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6 July 2018

Blockade of PD-1/B7-H1 interaction restores effector CD8+ T cell responses in a hepatitis C virus core murine model

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PD-1 and its ligands in tolerance and immunity

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CD8 T cell dysfunction during chronic viral infection.

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6 July 2018

Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses

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6 July 2018

Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

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The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design

1 reference

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6 July 2018

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6 July 2018

Restoring function in exhausted CD8 T cells during chronic viral infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005104

6 July 2018

CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms

1 reference

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6 July 2018

IL-15: targeting CD8+ T cells for immunotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005104

6 July 2018

Tumor immunotherapy: preclinical and clinical activity of anti-CTLA4 antibodies

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6 July 2018

Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function.

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6 July 2018

Role of trans-cellular IL-15 presentation in the activation of NK cell-mediated killing, which leads to enhanced tumor immunosurveillance

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Importance of IL-10 for CTLA-4-mediated inhibition of tumor-eradicating immunity

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IL-15Ralpha recycles and presents IL-15 In trans to neighboring cells

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Interleukin 15 controls both proliferation and survival of a subset of memory-phenotype CD8(+) T cells

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1 reference

https://pubmed.ncbi.nlm.nih.gov/20924130

12 December 2020

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10.1158/1078-0432.CCR-10-1966

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15 February 2020

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15 February 2020

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15 February 2020

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