Mutational analysis of the structural organization of polyglutamine aggregates (Q34430560)

2 August 2017

Mutational analysis of the structural organization of polyglutamine aggregates (English)

1 reference

2 August 2017

1 reference

Ashwani K Thakur

1

1 reference

PubMed ID

12444250

2 August 2017

Ronald Wetzel

series ordinal

2

1 reference

PubMed ID

12444250

2 August 2017

language of work or name

English

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publication date

20 November 2002

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Proceedings of the National Academy of Sciences of the United States of America

2 August 2017

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2 August 2017

99

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2 August 2017

26

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2 August 2017

17014-17019

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A linear lattice model for polyglutamine in CAG-expansion diseases

2 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139261

Huntington's disease age-of-onset linked to polyglutamine aggregation nucleation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139261

Ideas of order for amyloid fibril structure

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139261

Amyloid fibers are water-filled nanotubes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139261

A protein sequence that can encode native structure by disfavoring alternate conformations

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139261

Conformational Abs recognizing a generic amyloid fibril epitope

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139261

The architecture of parallel beta-helices and related folds

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139261

Design of folded peptides

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139261

Length-dependent stability and strand length limits in antiparallel -sheet secondary structure

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139261

Solubilization and disaggregation of polyglutamine peptides

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139261

Huntington's disease: the challenge for cell biologists

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139261

Abeta amyloid fibrils possess a core structure highly resistant to hydrogen exchange

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139261

Fourteen and counting: unraveling trinucleotide repeat diseases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139261

Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139261

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139261

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139261

Models of amyloid seeding in Alzheimer's disease and scrapie: mechanistic truths and physiological consequences of the time-dependent solubility of amyloid proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139261

Point substitution in the central hydrophobic cluster of a human beta-amyloid congener disrupts peptide folding and abolishes plaque competence

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139261

Trinucleotide repeats and long homopeptides in genes and proteins associated with nervous system disease and development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139261

Structure of beta-crystallite assemblies formed by Alzheimer beta-amyloid protein analogues: analysis by x-ray diffraction.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139261

Intranuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3.

6 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.252523899

Aggregated polyglutamine peptides delivered to nuclei are toxic to mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.252523899

Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.252523899

Polyglutamine aggregation behavior in vitro supports a recruitment mechanism of cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.252523899

Solution structure of polyglutamine tracts in GST-polyglutamine fusion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.252523899

Amyloid-like features of polyglutamine aggregates and their assembly kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.252523899

Photoaffinity cross-linking of Alzheimer's disease amyloid fibrils reveals interstrand contact regions between assembled beta-amyloid peptide subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.252523899

Structural and dynamic features of Alzheimer's Abeta peptide in amyloid fibrils studied by site-directed spin labeling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.252523899

Effects of sequential proline substitutions on amyloid formation by human amylin20-29.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.252523899

Aggregation and neurotoxicity of mutant amyloid beta (A beta) peptides with proline replacement: importance of turn formation at positions 22 and 23.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.252523899

Amyloid beta-protein fibrillogenesis. Detection of a protofibrillar intermediate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.252523899

Analysis of protein aggregation kinetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.252523899

Folding of oligoglutamines: a theoretical approach based upon thermodynamics and molecular mechanics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.252523899

Structural features of the Abeta amyloid fibril elucidated by limited proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.252523899

Prolines and amyloidogenicity in fragments of the Alzheimer's peptide beta/A4

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.252523899

Observation of metastable Abeta amyloid protofibrils by atomic force microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.252523899

21 January 2018

Identifiers

DOI

10.1073/PNAS.252523899

1 reference

2 August 2017

0 references

1 reference

2 August 2017

1 reference

PubMed ID

12444250