A phase I dose-escalation study to a predefined dose of a transforming growth factor-β1 monoclonal antibody (TβM1) in patients with metastatic cancer (Q34432864)

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English	A phase I dose-escalation study to a predefined dose of a transforming growth factor-β1 monoclonal antibody (TβM1) in patients with metastatic cancer	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

2 August 2017

A phase I dose-escalation study to a predefined dose of a transforming growth factor-β1 monoclonal antibody (TβM1) in patients with metastatic cancer (English)

1 reference

Europe PubMed Central

2 August 2017

author name string

Allen Cohn

1

1 reference

Europe PubMed Central

2 August 2017

Michael M Lahn

2

1 reference

Europe PubMed Central

2 August 2017

Kristen E Williams

3

1 reference

Europe PubMed Central

2 August 2017

Ann L Cleverly

4

1 reference

Europe PubMed Central

2 August 2017

Celine Pitou

5

1 reference

Europe PubMed Central

2 August 2017

Sunil K Kadam

6

1 reference

Europe PubMed Central

2 August 2017

Mark W Farmen

7

1 reference

Europe PubMed Central

2 August 2017

Durisala Desaiah

8

1 reference

Europe PubMed Central

2 August 2017

Robert Raju

9

1 reference

Europe PubMed Central

2 August 2017

Paul Conkling

10

1 reference

Europe PubMed Central

2 August 2017

Donald Richards

11

1 reference

Europe PubMed Central

2 August 2017

publication date

26 September 2014

1 reference

Europe PubMed Central

2 August 2017

International Journal of Oncology

1 reference

Europe PubMed Central

2 August 2017

45

1 reference

Europe PubMed Central

2 August 2017

6

1 reference

Europe PubMed Central

2 August 2017

2221-2231

1 reference

Europe PubMed Central

2 August 2017

Antibody targeting of TGF-β in cancer patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215585

6 July 2018

A phase 1, single-dose study of fresolimumab, an anti-TGF-β antibody, in treatment-resistant primary focal segmental glomerulosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215585

6 July 2018

Analysis and variability of TGFbeta measurements in cancer patients with skeletal metastases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215585

6 July 2018

Dual role of transforming growth factor beta in mammary tumorigenesis and metastatic progression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215585

6 July 2018

Development of TGF-beta signalling inhibitors for cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215585

6 July 2018

Antibody pharmacokinetics and pharmacodynamics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215585

6 July 2018

Monoclonal antibodies in cancer therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215585

6 July 2018

Association of pre- and postoperative plasma levels of transforming growth factor beta(1) and interleukin 6 and its soluble receptor with prostate cancer progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215585

6 July 2018

Tumor-suppressive and promoting function of transforming growth factor beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215585

6 July 2018

Synthesis and activity of new aryl- and heteroaryl-substituted pyrazole inhibitors of the transforming growth factor-beta type I receptor kinase domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215585

6 July 2018

Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215585

6 July 2018

Transforming growth factor-beta1 in invasion and metastasis in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215585

6 July 2018

Lifetime exposure to a soluble TGF-beta antagonist protects mice against metastasis without adverse side effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215585

6 July 2018

Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215585

6 July 2018

The disposition (ADME) of antisense oligonucleotides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215585

6 July 2018

Enhanced tumorigenesis and reduced transforming growth factor-beta type II receptor in lung tumors from mice with reduced gene dosage of transforming growth factor-beta1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215585

6 July 2018

Role of transforming growth factor-beta signaling in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215585

6 July 2018

Mitogenic conversion of transforming growth factor-beta1 effect by oncogenic Ha-Ras-induced activation of the mitogen-activated protein kinase signaling pathway in human prostate cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215585

6 July 2018

Elevated levels of circulating interleukin-6 and transforming growth factor-beta1 in patients with metastatic prostatic carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215585

6 July 2018

TGF-beta signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215585

6 July 2018

Determinants of specificity in TGF-beta signal transduction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215585

6 July 2018

Risks and benefits of phase 1 oncology trials, 1991 through 2002.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215585

27 October 2018

The addition of interleukin-6 soluble receptor and transforming growth factor beta1 improves a preoperative nomogram for predicting biochemical progression in patients with clinically localized prostate cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215585

27 October 2018

Increased TGFbeta1 plasma level in patients with lung cancer: potential mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215585

27 October 2018

Application of T cell-based transcriptomics to identify three candidate biomarkers for monitoring anti-TGFβR therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4215585

9 December 2018

TGF-β signalling-related markers in cancer patients with bone metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25270361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preoperative plasma levels of transforming growth factor beta(1) (TGF-beta(1)) strongly predict progression in patients undergoing radical prostatectomy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25270361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma transforming growth factor-beta 1 reflects disease status in patients with lung cancer after radiotherapy: a possible tumor marker

1 reference

https://pubmed.ncbi.nlm.nih.gov/25270361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated plasma levels of TGF-β1 in patients with invasive prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25270361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum levels of transforming growth factor beta1 in patients with breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25270361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated plasma transforming growth factor-beta 1 levels in breast cancer patients decrease after surgical removal of the tumor

1 reference

https://pubmed.ncbi.nlm.nih.gov/25270361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An expression index for Affymetrix GeneChips based on the generalized logarithm

1 reference

https://pubmed.ncbi.nlm.nih.gov/25270361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circulating transforming growth factor beta 1 as a predictor of liver metastasis after resection in colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25270361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated serum levels of transforming growth factor-beta1 in patients with colorectal carcinoma: its association with tumor progression and its significant decrease after curative surgical resection

1 reference

https://pubmed.ncbi.nlm.nih.gov/25270361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevation of serum transforming growth factor-β1 Level in patients with metastatic prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25270361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma transforming growth factor-beta1 level before radiotherapy correlates with long term outcome of patients with lung carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/25270361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3892/IJO.2014.2679

1 reference

Europe PubMed Central

2 August 2017

release_unx4nespl5b4fgp3bxiw4bwjem

1 reference

https://api.fatcat.wiki/v0/release/unx4nespl5b4fgp3bxiw4bwjem

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

2 August 2017

1 reference

Europe PubMed Central

2 August 2017

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