Receptor signaling and structure: insights from serotonin-1 receptors (Q34432932)

2 August 2017

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title

Receptor signaling and structure: insights from serotonin-1 receptors (English)

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2 August 2017

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Albert PR

1

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PubMed ID

11701344

2 August 2017

Tiberi M

series ordinal

2

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2 August 2017

1 December 2001

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Trends in Endocrinology and Metabolism

2 August 2017

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2 August 2017

12

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2 August 2017

10

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2 August 2017

453-460

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The structure and signalling properties of 5-HT receptors: an endless diversity?

2 August 2017

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The recombinant 5-HT1A receptor: G protein coupling and signalling pathways.

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The 5-HT1A receptor: signaling, desensitization, and gene transcription

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Dissecting the role of the serotonin system in neuropsychiatric disorders using knockout mice

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Cell communication networks: epidermal growth factor receptor transactivation as the paradigm for interreceptor signal transmission

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7 January 2021

New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades

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7 January 2021

Activation of a mitogen-activated protein kinase (ERK2) by the 5-hydroxytryptamine1A receptor is sensitive not only to inhibitors of phosphatidylinositol 3-kinase, but to an inhibitor of phosphatidylcholine hydrolysis

1 reference

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7 January 2021

Ras-dependent activation of fibroblast mitogen-activated protein kinase by 5-HT1A receptor via a G protein beta gamma-subunit-initiated pathway.

1 reference

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7 January 2021

Rapid activation of sodium-proton exchange and extracellular signal-regulated protein kinase in fibroblasts by G protein-coupled 5-HT1A receptor involves distinct signalling cascades.

1 reference

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7 January 2021

Serotonin 5-HT1A receptor-mediated Erk activation requires calcium/calmodulin-dependent receptor endocytosis

1 reference

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7 January 2021

5-Hydroxytryptamine1A receptor/Gibetagamma stimulates mitogen-activated protein kinase via NAD(P)H oxidase and reactive oxygen species upstream of src in chinese hamster ovary fibroblasts

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7 January 2021

EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF

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7 January 2021

Autoregulation of cell-specific MAP kinase control of the tryptophan hydroxylase promoter.

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7 January 2021

Differential regulation of mitogen-activated protein kinase-responsive genes by the duration of a calcium signal

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7 January 2021

Expression of the human 5-hydroxytryptamine1A receptor in Sf9 cells. Reconstitution of a coupled phenotype by co-expression of mammalian G protein subunits

1 reference

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7 January 2021

Human 5-HT1 receptor subtypes exhibit distinct G protein coupling behaviors in membranes from Sf9 cells

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7 January 2021

Stimulation of cAMP synthesis by Gi-coupled receptors upon ablation of distinct Galphai protein expression. Gi subtype specificity of the 5-HT1A receptor

1 reference

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7 January 2021

QEHA27, a peptide that binds to G-protein beta gamma-subunits, reduces the inhibitory effect of 5-HT on the Ca2+ current of rat dorsal raphe neurons.

1 reference

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7 January 2021

Distinct Roles for Gαi2, Gαi3, and Gβγ in Modulation of Forskolin- or Gs-mediated cAMP Accumulation and Calcium Mobilization by Dopamine D2S Receptors

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7 January 2021

Pharmacological characterisation of 5-HT receptors positively coupled to adenylyl cyclase in the rat hippocampus.

1 reference

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7 January 2021

5-HT1A receptor activates Na+/H+ exchange in CHO-K1 cells through Gialpha2 and Gialpha3.

1 reference

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7 January 2021

Fluorescent BODIPY-GTP analogs: real-time measurement of nucleotide binding to G proteins

1 reference

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7 January 2021

Stimulated [35S]GTP gamma S binding by 5-HT1A receptor agonists in recombinant cell lines. Modulation of apparent efficacy by G-protein activation state

1 reference

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7 January 2021

Inhibition of the constitutive activity of human 5-HT1A receptors by the inverse agonist, spiperone but not the neutral antagonist, WAY 100,635

1 reference

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7 January 2021

Mechanisms of agonism and inverse agonism at serotonin 5-HT1A receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2801%2900498-2

7 January 2021

Constitutive G(i2)-dependent activation of adenylyl cyclase type II by the 5-HT1A receptor. Inhibition by anxiolytic partial agonists

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2801%2900498-2

7 January 2021

Site-directed mutations in the third intracellular loop of the serotonin 5-HT(1A) receptor alter G protein coupling from G(i) to G(s) in a ligand-dependent manner

1 reference

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7 January 2021

Inverse agonism: pharmacological curiosity or potential therapeutic strategy?

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2801%2900498-2

7 January 2021

Adenylyl cyclase regulates signal onset via the inhibitory GTP-binding protein, Gi

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2801%2900498-2

7 January 2021

Inverse agonism and constitutive activity as functional correlates of serotonin h5-HT(1B) receptor/G-protein stoichiometry

1 reference

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7 January 2021

Activation of constitutive 5-hydroxytryptamine(1B) receptor by a series of mutations in the BBXXB motif: positioning of the third intracellular loop distal junction and its G(o)alpha protein interactions

1 reference

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7 January 2021

Two amino acids within the alpha4 helix of Galphai1 mediate coupling with 5-hydroxytryptamine1B receptors

1 reference

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7 January 2021

Agonist selective regulation of G proteins by cannabinoid CB(1) and CB(2) receptors

1 reference

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7 January 2021

Coupling efficacy and selectivity of the human mu-opioid receptor expressed as receptor-Galpha fusion proteins in Escherichia coli.

1 reference

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7 January 2021

Characterization of 5-HT1A receptor-mediated [35S]GTPgammaS binding in rat hippocampal membranes

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2801%2900498-2

7 January 2021

High constitutive activity of native H3 receptors regulates histamine neurons in brain.

1 reference

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7 January 2021

Agonist-induced desensitization and phosphorylation of human 5-HT1A receptor expressed in Sf9 insect cells.

1 reference

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7 January 2021

Activation of the beta(2)-adrenergic receptor-Galpha(s) complex leads to rapid depalmitoylation and inhibition of repalmitoylation of both the receptor and Galpha(s).

1 reference

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7 January 2021

Regulation of galpha i palmitoylation by activation of the 5-hydroxytryptamine-1A receptor

1 reference

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7 January 2021

Crystal structure of rhodopsin: A G protein-coupled receptor

1 reference

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7 January 2021

G-proteins are involved in 5-HT receptor-mediated modulation of N- and P/Q- but not T-type Ca2+ channels

1 reference

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7 January 2021

Structural variants of a human 5-HT1a receptor intracellular loop 3 peptide

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2801%2900498-2

7 January 2021

A conserved threonine residue in the second intracellular loop of the 5-hydroxytryptamine 1A receptor directs signaling specificity.

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2801%2900498-2

7 January 2021

A Putative alpha-helical Gbetagamma-coupling Domain in the Second Intracellular Loop of the 5-HT1A Receptora

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2801%2900498-2

7 January 2021

10.1016/S1043-2760(01)00498-2

Identifiers

DOI

1 reference

2 August 2017

1 reference

PubMed ID

11701344