Voltage-gated sodium channel Nav1.6 is modulated by p38 mitogen-activated protein kinase. (Q34433609)

2 August 2017

Voltage-gated sodium channel Nav1.6 is modulated by p38 mitogen-activated protein kinase (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725417&resulttype=core&format=json

12 May 2020

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Ellen K Wittmack

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725417&resulttype=core&format=json

12 May 2020

Anthony M Rush

2

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12 May 2020

Andy Hudmon

3

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12 May 2020

Stephen G Waxman

4

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12 May 2020

Sulayman D Dib-Hajj

5

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12 May 2020

language of work or name

English

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publication date

1 July 2005

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2 August 2017

Journal of Neuroscience

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12 May 2020

volume

25

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12 May 2020

issue

28

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12 May 2020

page(s)

6621-6630

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Function of WW domains as phosphoserine- or phosphothreonine-binding modules

12 May 2020

cites work

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12 December 2020

cAMP-dependent phosphorylation of the tetrodotoxin-resistant voltage-dependent sodium channel SNS.

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12 December 2020

Nedd4-like proteins: an emerging family of ubiquitin-protein ligases implicated in diverse cellular functions

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12 December 2020

MEK1 protein kinase inhibition protects against damage resulting from focal cerebral ischemia

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12 December 2020

New insights into the control of MAP kinase pathways

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12 December 2020

Regulation of the cardiac voltage-gated Na+ channel (H1) by the ubiquitin-protein ligase Nedd4.

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12 December 2020

Sodium channel Na(v)1.6 is localized at nodes of ranvier, dendrites, and synapses

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12 December 2020

p38 MAP kinases: beyond the stress response

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12 December 2020

Activation of mitogen-activated protein kinases after transient forebrain ischemia in gerbil hippocampus

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12 December 2020

Structural basis for phosphoserine-proline recognition by group IV WW domains

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12 December 2020

Docking domains and substrate-specificity determination for MAP kinases

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12 December 2020

The A-type potassium channel Kv4.2 is a substrate for the mitogen-activated protein kinase ERK.

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12 December 2020

SB 239063, a second-generation p38 mitogen-activated protein kinase inhibitor, reduces brain injury and neurological deficits in cerebral focal ischemia.

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12 December 2020

NeW wrinkles for an old domain

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12 December 2020

Compact myelin dictates the differential targeting of two sodium channel isoforms in the same axon.

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12 December 2020

Differential control of clustering of the sodium channels Na(v)1.2 and Na(v)1.6 at developing CNS nodes of Ranvier

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12 December 2020

Neuromodulation of Na+ channels: an unexpected form of cellular plasticity

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12 December 2020

Determinants of ligand specificity in groups I and IV WW domains as studied by surface plasmon resonance and model building.

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12 December 2020

Protein kinase modulation of dendritic K+ channels in hippocampus involves a mitogen-activated protein kinase pathway.

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12 December 2020

Docking interactions in the mitogen-activated protein kinase cascades

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12 December 2020

Molecular mechanism of convergent regulation of brain Na(+) channels by protein kinase C and protein kinase A anchored to AKAP-15.

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12 December 2020

p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia

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12 December 2020

Sodium channel Na(v)1.6 is expressed along nonmyelinated axons and it contributes to conduction.

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12 December 2020

Destabilization of Nav1.7 Sodium Channel α-Subunit mRNA by Constitutive Phosphorylation of Extracellular Signal-Regulated Kinase: Negative Regulation of Steady-State Level of Cell Surface Functional Sodium Channels in Adrenal Chromaffin Cells

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12 December 2020

p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain.

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12 December 2020

Distinct repriming and closed-state inactivation kinetics of Nav1.6 and Nav1.7 sodium channels in mouse spinal sensory neurons

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12 December 2020

Calmodulin binds to the C terminus of sodium channels Nav1.4 and Nav1.6 and differentially modulates their functional properties.

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12 December 2020

Functional modulation of brain sodium channels by cAMP-dependent phosphorylation

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12 December 2020

Activation of p38 mitogen-activated protein kinase in spinal hyperactive microglia contributes to pain hypersensitivity following peripheral nerve injury

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12 December 2020

Modulation of Nav1.7 and Nav1.8 peripheral nerve sodium channels by protein kinase A and protein kinase C.

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12 December 2020

Co-localization of sodium channel Nav1.6 and the sodium-calcium exchanger at sites of axonal injury in the spinal cord in EAE.

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12 December 2020

Anisomycin downregulates gap-junctional intercellular communication via the p38 MAP-kinase pathway

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12 December 2020

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

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12 December 2020

Molecular changes in neurons in multiple sclerosis: altered axonal expression of Nav1.2 and Nav1.6 sodium channels and Na+/Ca2+ exchanger

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12 December 2020

Cardiac voltage-gated sodium channel Nav1.5 is regulated by Nedd4-2 mediated ubiquitination

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12 December 2020

Mitogen-activated protein kinase p38 mediates reduced nerve conduction velocity in experimental diabetic neuropathy: interactions with aldose reductase

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12 December 2020

Acquired dendritic channelopathy in temporal lobe epilepsy

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12 December 2020

Fibroblast growth factor homologous factor 2B: association with Nav1.6 and selective colocalization at nodes of Ranvier of dorsal root axons

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12 December 2020

Sodium channels contribute to microglia/macrophage activation and function in EAE and MS.

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12 December 2020

Role of mitogen-activated protein kinase activation in injured and intact primary afferent neurons for mechanical and heat hypersensitivity after spinal nerve ligation.

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12 December 2020

Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins

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12 December 2020

Electrophysiological properties of two axonal sodium channels, Nav1.2 and Nav1.6, expressed in mouse spinal sensory neurones

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12 December 2020

Nav1.6 channels generate resurgent sodium currents in spinal sensory neurons

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12 December 2020

Simulations of conduction in uniform myelinated fibers. Relative sensitivity to changes in nodal and internodal parameters

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12 December 2020

Parallel signal processing among mammalian MAPKs

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12 December 2020

A novel, abundant sodium channel expressed in neurons and glia

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12 December 2020

A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

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12 December 2020

Conduction slowing without conduction block of compound muscle and nerve action potentials due to sodium channel block.

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12 December 2020

Solubilization and purification of enzymatically active glutathione S-transferase (pGEX) fusion proteins

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12 December 2020

ERK6, a mitogen-activated protein kinase involved in C2C12 myoblast differentiation

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12 December 2020

Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta)

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12 December 2020

The primary structure of p38 gamma: a new member of p38 group of MAP kinases

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12 December 2020

SAP kinase-3, a new member of the family of mammalian stress-activated protein kinases

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12 December 2020

Spinal sensory neurons express multiple sodium channel alpha-subunit mRNAs.

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12 December 2020

Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38delta

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12 December 2020

Functional analysis of the rat I sodium channel in xenopus oocytes.

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12 December 2020

Modulation of TTX-R INa by PKC and PKA and their role in PGE2-induced sensitization of rat sensory neurons in vitro.

1 reference

12 December 2020

10.1523/JNEUROSCI.0541-05.2005

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725417&resulttype=core&format=json

12 May 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725417&resulttype=core&format=json

12 May 2020

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