Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition. (Q34433867)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129481%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

title

Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition (English)

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12 March 2020

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1 reference

3

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12 March 2020

Claire A Higgins

5

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12 March 2020

author name string

Luzhou Xing

1

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12 March 2020

Zhenpeng Dai

2

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12 March 2020

Jane E Cerise

4

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12 March 2020

Weijuan Gong

6

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12 March 2020

Annemieke de Jong

7

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12 March 2020

Sivan Harel

8

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12 March 2020

Gina M DeStefano

9

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Lisa Rothman

10

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12 March 2020

Pallavi Singh

11

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12 March 2020

Lynn Petukhova

12

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12 March 2020

Julian Mackay-Wiggan

13

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12 March 2020

Angela M Christiano

14

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12 March 2020

Raphael Clynes

15

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12 March 2020

language of work or name

English

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publication date

17 August 2014

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12 March 2020

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12 March 2020

volume

20

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12 March 2020

page(s)

1043-1049

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12 March 2020

issue

9

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https://scigraph.springernature.com/pub.10.1038/nm.3645

12 March 2020

exact match

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cites work

Abnormal interactions between perifollicular mast cells and CD8+ T-cells may contribute to the pathogenesis of alopecia areata

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362521

Janus kinase inhibitors in autoimmune diseases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362521

Transcriptional insights into the CD8(+) T cell response to infection and memory T cell formation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362521

Molecular definition of the identity and activation of natural killer cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362521

JAK inhibition with ruxolitinib versus best available therapy for myelofibrosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362521

Modulation of innate and adaptive immune responses by tofacitinib (CP-690,550).

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362521

Contribution of astrocyte-derived IL-15 to CD8 T cell effector functions in multiple sclerosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362521

Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362521

Genome-wide association study in alopecia areata implicates both innate and adaptive immunity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362521

Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362521

The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362521

Reprogramming of CTLs into natural killer-like cells in celiac disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362521

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362521

Gene Expression Dynamics Inspector (GEDI): for integrative analysis of expression profiles.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362521

Interleukin 15: biology and relevance to human disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362521

Autoimmune hair loss (alopecia areata) transferred by T lymphocytes to human scalp explants on SCID mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362521

6 July 2018

1 reference

Coordinated induction by IL15 of a TCR-independent NKG2D signaling pathway converts CTL into lymphokine-activated killer cells in celiac disease.

21 January 2018

1 reference

Interferon-gamma-deficient mice are resistant to the development of alopecia areata.

21 January 2018

1 reference

Reduced Expression of Interleukin-2 Decreases the Frequency of Alopecia Areata Onset in C3H/HeJ Mice

21 January 2018

1 reference

Preliminary clinical activity of a topical JAK1/2 inhibitor in the treatment of psoriasis.

21 January 2018

1 reference

Companies hope for kinase inhibitor JAKpot.

21 January 2018

1 reference

Transfer of CD8(+) cells induces localized hair loss whereas CD4(+)/CD25(-) cells promote systemic alopecia areata and CD4(+)/CD25(+) cells blockade disease onset in the C3H/HeJ mouse model

21 January 2018

1 reference

12 December 2020

Alopecia areata induced in C3H/HeJ mice by interferon-gamma: evidence for loss of immune privilege

1 reference

12 December 2020

Maintenance of hair follicle immune privilege is linked to prevention of NK cell attack

1 reference

12 December 2020

Alopecia areata in aging C3H/HeJ mice

1 reference

12 December 2020

Interleukin-2 receptor alpha-chain expression in patients with alopecia areata

1 reference

12 December 2020

Interleukin-15 induces the expression of mRNAs of cytolytic mediators and augments cytotoxic activities in primary murine lymphocytes

1 reference

12 December 2020

Experimental induction of alopecia areata-like hair loss in C3H/HeJ mice using full-thickness skin grafts

1 reference

12 December 2020

Identifiers

DOI

10.1038/NM.3645

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129481%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25129481%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

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