Structure function studies: identification of vitamin D analogs for the ligand-binding domains of important proteins in the vitamin D-endocrine system (Q34436436)

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English	Structure function studies: identification of vitamin D analogs for the ligand-binding domains of important proteins in the vitamin D-endocrine system	scientific article

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scholarly article

1 reference

Europe PubMed Central

2 August 2017

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Europe PubMed Central

Structure function studies: identification of vitamin D analogs for the ligand-binding domains of important proteins in the vitamin D-endocrine system (English)

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Europe PubMed Central

2 August 2017

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author name string

Norman AW

1

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Europe PubMed Central

2 August 2017

Silva FR

2

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Europe PubMed Central

2 August 2017

publication date

1 April 2001

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Europe PubMed Central

2 August 2017

Reviews in Endocrine and Metabolic Disorders

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Europe PubMed Central

2 August 2017

2

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Europe PubMed Central

2 August 2017

2

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Europe PubMed Central

2 August 2017

229-238

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Europe PubMed Central

2 August 2017

https://scigraph.springernature.com/pub.10.1023/a:1010067030049

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Antitumor effect of 22-oxa-calcitriol, a noncalcemic analogue of calcitriol, in athymic mice implanted with human breast carcinoma and its synergism with tamoxifen

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https://pubmed.ncbi.nlm.nih.gov/11705328

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Evidence on the participation of the 3',5'-cyclic AMP pathway in the non-genomic action of 1,25-dihydroxy-vitamin D3 in cardiac muscle

1 reference

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12 December 2020

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Toxicity and dose-response studies of 1,25-(OH)2-16-ene-23-yne vitamin D3 in transgenic mice

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12 December 2020

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Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid

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12 December 2020

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Antagonistic Actions in Vivo of (23S)-25-Dehydro-1alpha-Hydroxyvitamin D(3-)26,23-Lactone on Calcium Metabolism Induced by 1alpha,25-Dihydroxyvitamin D(3).

1 reference

https://pubmed.ncbi.nlm.nih.gov/11705328

12 December 2020

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A functional cell surface type receptor is required for the early action of 1,25-dihydroxyvitamin D3 on the phosphoinositide metabolism in rat enterocytes

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12 December 2020

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Identification of a membrane receptor for 1,25-dihydroxyvitamin D3 which mediates rapid activation of protein kinase C.

1 reference

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Inhibition of proliferation of prostate cancer cells by a 19-nor-hexafluoride vitamin D3 analogue involves the induction of p21waf1, p27kip1 and E-cadherin

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19-Nor-1-alpha-25-dihydroxyvitamin D2 (Paricalcitol) safely and effectively reduces the levels of intact parathyroid hormone in patients on hemodialysis

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Rapid actions of 1α,25-dihydroxyvitamin D3 on Ca2+ and phospholipids in isolated rat liver nuclei

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Stimulation by 1alpha,25(OH)2-vitamin D3 of whole cell chloride currents in osteoblastic ROS 17/2.8 cells. A structure-function study

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Physiological importance of the 1,25(OH)2D3 membrane receptor and evidence for a membrane receptor specific for 24,25(OH)2D3

1 reference

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Sensitive induction of apoptosis in breast cancer cells by a novel 1,25-dihydroxyvitamin D3 analogue shows relation to promoter selectivity

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Receptors for 1alpha,25(OH)2D3: past, present, and future

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Differential interaction of 1alpha,25-dihydroxyvitamin D3 analogues and their 20-epi homologues with the vitamin D receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/11705328

12 December 2020

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Demonstration that 1 beta,25-dihydroxyvitamin D3 is an antagonist of the nongenomic but not genomic biological responses and biological profile of the three A-ring diastereomers of 1 alpha,25-dihydroxyvitamin D3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11705328

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based on heuristic

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Rapid effects of 1,25-dihydroxyvitamin D3 and extracellular Ca2+ on phospholipid metabolism in dispersed porcine parathyroid cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11705328

12 December 2020

based on heuristic

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Vitamin D hydroxylases

1 reference

https://pubmed.ncbi.nlm.nih.gov/11705328

12 December 2020

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A structural role for hormone in the thyroid hormone receptor.

1 reference

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Arocalciferols: synthesis and biological evaluation of aromatic side-chain analogues of 1 alpha,25-dihydroxyvitamin D3(1a).

1 reference

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An update on vitamin D3 analogues in the treatment of psoriasis

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The nuclear receptor superfamily: the second decade

1 reference

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Effects of 1,25-dihydroxyvitamin D3 and its 20-epi analogues (MC 1288, MC 1301, KH 1060), on clonal keratinocyte growth: evidence for differentiation of keratinocyte stem cells and analysis of the modulatory effects of cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/11705328

12 December 2020

based on heuristic

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Monocytic differentiation of acute promyelocytic leukemia cells in response to 1,25-dihydroxyvitamin D3 is independent of nuclear receptor binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/11705328

12 December 2020

based on heuristic

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Membrane receptors for steroid hormones: a case for specific cell surface binding sites for vitamin D metabolites and estrogens.

1 reference

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Vitamin D3 metabolites modulate dihydropyridine-sensitive calcium currents in clonal rat osteosarcoma cells.

1 reference

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1alpha,24-dihydroxyvitamin D3 (tacalcitol) is effective against Hailey-Hailey disease both in vivo and in vitro

1 reference

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based on heuristic

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The nuclear vitamin D receptor: biological and molecular regulatory properties revealed.

1 reference

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12 December 2020

based on heuristic

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Apoptosis induced by vitamin D compounds in breast cancer cells is inhibited by Bcl-2 but does not involve known caspases or p53

1 reference

https://pubmed.ncbi.nlm.nih.gov/11705328

12 December 2020

based on heuristic

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An insulinotropic effect of vitamin D analog with increasing intracellular Ca2+ concentration in pancreatic beta-cells through nongenomic signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/11705328

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based on heuristic

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Distinct conformational changes induced by 20-epi analogues of 1 alpha,25-dihydroxyvitamin D3 are associated with enhanced activation of the vitamin D receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/11705328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of 6-s-cis- and 6-s-trans-locked analogs of 1alpha,25-dihydroxyvitamin D3 indicates that the 6-s-cis conformation is preferred for rapid nongenomic biological responses and that neither 6-s-cis- nor 6-s-trans-locked analogs are preferred

1 reference

https://pubmed.ncbi.nlm.nih.gov/11705328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1,25-Dihydroxy-16-ene-23-yne-vitamin D3 prolongs survival time of leukemic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/11705328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium transport in perfused duodena from normal chicks: enhancement within fourteen minutes of exposure to 1,25-dihydroxyvitamin D3

1 reference

https://pubmed.ncbi.nlm.nih.gov/11705328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vitamin D: structure-function analyses and the design of analogs.

1 reference

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12 December 2020

based on heuristic

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20-EPI-vitamin D3 analogues: A novel class of potent regulators of cell growth and immune responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/11705328

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based on heuristic

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Regulation of 1,25-dihydroxyvitamin D3 production by cultured alveolar macrophages from normal human donors and from patients with pulmonary sarcoidosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11705328

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based on heuristic

inferred from PubMed ID database lookup

Profile of ligand specificity of the vitamin D binding protein for 1 alpha,25-dihydroxyvitamin D3 and its analogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/11705328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear-receptor ligands and ligand-binding domains

1 reference

https://pubmed.ncbi.nlm.nih.gov/11705328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

24R,25-dihydroxyvitamin D3: an essential vitamin D3 metabolite for both normal bone integrity and healing of tibial fracture in chicks

1 reference

https://pubmed.ncbi.nlm.nih.gov/11705328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-function relationships in the vitamin D endocrine system

1 reference

https://pubmed.ncbi.nlm.nih.gov/11705328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

19-nor vitamin-D analogs: a new class of potent inhibitors of proliferation and inducers of differentiation of human myeloid leukemia cell lines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11705328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of parathyroid hormone secretion in hemodialysis patients by a novel vitamin D analogue: 19-nor-1,25-dihydroxyvitamin D2

1 reference

https://pubmed.ncbi.nlm.nih.gov/11705328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding characteristics of a membrane receptor that recognizes 1α25-dihydroxyvitamin D3 and its epimer, 1β,25-dihydroxyvitamin D3

1 reference

https://pubmed.ncbi.nlm.nih.gov/11705328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitumor effect of 22-oxacalcitriol on estrogen receptor-negative MDA-MB-231 tumors in athymic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/11705328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-function studies of 1,25-dihydroxyvitamin D3 and the vitamin D endocrine system. 1,25-dihydroxy-pentadeuterio-previtamin D3 (as a 6-s-cis analog) stimulates nongenomic but not genomic biological responses.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11705328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antagonistic action of novel 1alpha,25-dihydroxyvitamin D3-26, 23-lactone analogs on differentiation of human leukemia cells (HL-60) induced by 1alpha,25-dihydroxyvitamin D3

1 reference

https://pubmed.ncbi.nlm.nih.gov/11705328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of phosphorylation of mitogen-activated protein kinase by 1alpha,25-dihydroxyvitamin D3 in promyelocytic NB4 leukemia cells: a structure-function study

1 reference

https://pubmed.ncbi.nlm.nih.gov/11705328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunomodulatory effects of vitamin D analog KH1060 on an experimental skin transplantation model

1 reference

https://pubmed.ncbi.nlm.nih.gov/11705328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a specific binding protein for 1 alpha,25-dihydroxyvitamin D3 in basal-lateral membranes of chick intestinal epithelium and relationship to transcaltachia

1 reference

https://pubmed.ncbi.nlm.nih.gov/11705328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/A:1010067030049

1 reference

Europe PubMed Central

2 August 2017

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1 reference

Europe PubMed Central

2 August 2017

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