A high degree of LINE-1 hypomethylation is a unique feature of early-onset colorectal cancer (Q34438078)

2 August 2017

A high degree of LINE-1 hypomethylation is a unique feature of early-onset colorectal cancer (English)

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2 August 2017

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Ajay Goel

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ORCID Public Data File 2021

Leticia Moreira

object named as

Leticia Moreira

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ORCID Public Data File 2021

author name string

Marina Antelo

1

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2 August 2017

Francesc Balaguer

2

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2 August 2017

Jinru Shia

3

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2 August 2017

Yan Shen

4

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2 August 2017

Keun Hur

5

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2 August 2017

Miriam Cuatrecasas

7

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2 August 2017

Luis Bujanda

8

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2 August 2017

Maria Dolores Giraldez

9

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2 August 2017

Masanobu Takahashi

10

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2 August 2017

Ana Cabanne

11

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2 August 2017

Mario Edmundo Barugel

12

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2 August 2017

Mildred Arnold

13

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2 August 2017

Enrique Luis Roca

14

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2 August 2017

Montserrat Andreu

15

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2 August 2017

Sergi Castellvi-Bel

16

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2 August 2017

Xavier Llor

17

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2 August 2017

Rodrigo Jover

18

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2 August 2017

Antoni Castells

19

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2 August 2017

C Richard Boland

20

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2 August 2017

language of work or name

English

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publication date

25 September 2012

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2 August 2017

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2 August 2017

7

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2 August 2017

9

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2 August 2017

e45357

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Creative Commons Attribution 4.0 International

2 August 2017

start time

25 September 2012

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

MSH6 and MUTYH deficiency is a frequent event in early-onset colorectal cancer

1 reference

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The PREMM(1,2,6) model predicts risk of MLH1, MSH2, and MSH6 germline mutations based on cancer history

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458035

Low frequency of Lynch syndrome among young patients with non-familial colorectal cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458035

Epigenomic diversity of colorectal cancer indicated by LINE-1 methylation in a database of 869 tumors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458035

Hypomethylation of a LINE-1 promoter activates an alternate transcript of the MET oncogene in bladders with cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458035

Report from the Jerusalem workshop on Lynch syndrome-hereditary nonpolyposis colorectal cancer

6 July 2018

1 reference

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A method and server for predicting damaging missense mutations

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458035

An optimized pentaplex PCR for detecting DNA mismatch repair-deficient colorectal cancers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458035

Aberrant DNA methylation in hereditary nonpolyposis colorectal cancer without mismatch repair deficiency

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458035

Precision of pyrosequencing assay to measure LINE-1 methylation in colon cancer, normal colonic mucosa, and peripheral blood cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458035

6 July 2018

Cancer statistics, 2009

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458035

A cohort study of tumoral LINE-1 hypomethylation and prognosis in colon cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458035

Young-onset colorectal cancer in patients with no known genetic predisposition: can we increase early recognition and improve outcome?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458035

LINE-1 hypomethylation is inversely associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458035

6 July 2018

Epigenetics in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458035

Induction of DNA hypomethylation by tumor hypoxia.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458035

LINE-1 hypomethylation in cancer is highly variable and inversely correlated with microsatellite instability

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458035

The epigenomics of cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458035

Mechanisms of inactivation of MLH1 in hereditary nonpolyposis colorectal carcinoma: a novel approach

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458035

Recommendations for the care of individuals with an inherited predisposition to Lynch syndrome: a systematic review

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458035

CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458035

Genetic disruption of cytosine DNA methyltransferase enzymes induces chromosomal instability in human cancer cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458035

Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458035

Accuracy of revised Bethesda guidelines, microsatellite instability, and immunohistochemistry for the identification of patients with hereditary nonpolyposis colorectal cancer.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458035

A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458035

Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458035

Induction of Tumors in Mice by Genomic Hypomethylation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458035

Identification of MYH mutation carriers in colorectal cancer: a multicenter, case-control, population-based study.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458035

Chromosomal instability correlates with genome-wide DNA demethylation in human primary colorectal cancers.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458035

New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative group on HNPCC.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458035

Ten Years After Mutation Testing for Lynch Syndrome: Cancer Incidence and Outcome in Mutation-Positive and Mutation-Negative Family Members

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458035

Early-onset colorectal cancer with stable microsatellite DNA and near-diploid chromosomes

9 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458035

Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer

9 December 2018

1 reference

12 December 2020

Hereditary colorectal cancer

1 reference

12 December 2020

Hypomethylation of DNA from benign and malignant human colon neoplasms

1 reference

12 December 2020

Reduced genomic 5-methylcytosine content in human colonic neoplasia

1 reference

12 December 2020

Higher frequency of diploidy in young-onset microsatellite-stable colorectal cancer

1 reference

12 December 2020

Coexisting somatic promoter hypermethylation and pathogenic MLH1 germline mutation in Lynch syndrome

1 reference

12 December 2020

Increase in incidence of colorectal cancer among young men and women in the United States

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0045357

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DOI

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2 August 2017

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2 August 2017

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