Astrocyte-specific inactivation of the neurofibromatosis 1 gene (NF1) is insufficient for astrocytoma formation. (Q34441257)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12077339%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

title

Astrocyte-specific inactivation of the neurofibromatosis 1 gene (NF1) is insufficient for astrocytoma formation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12077339%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

0 references

1 reference

6

1 reference

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10 November 2019

author name string

Michaela Livia Bajenaru

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12077339%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Yuan Zhu

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12077339%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Nicolé M Hedrick

3

1 reference

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10 November 2019

Jessica Donahoe

4

1 reference

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10 November 2019

Luis F Parada

5

1 reference

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10 November 2019

language of work or name

English

0 references

publication date

1 July 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12077339%20AND%20SRC:MED&resulttype=core&format=json

Molecular and Cellular Biology

10 November 2019

published in

1 reference

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10 November 2019

volume

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12077339%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

page(s)

5100-5113

1 reference

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10 November 2019

issue

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12077339%20AND%20SRC:MED&resulttype=core&format=json

Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain

10 November 2019

cites work

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Neurofibromatosis 1 (NF1) heterozygosity results in a cell-autonomous growth advantage for astrocytes

6 July 2018

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6 July 2018

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Nf1;Trp53 mutant mice develop glioblastoma with evidence of strain-specific effects

6 July 2018

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6 July 2018

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Analysis of pilocytic astrocytoma by comparative genomic hybridization.

6 July 2018

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The PEN5 epitope identifies an oligodendrocyte precursor cell population and pilocytic astrocytomas

6 July 2018

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Haploinsufficiency for the neurofibromatosis 1 (NF1) tumor suppressor results in increased astrocyte proliferation

6 July 2018

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6 July 2018

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Absence of p53 gene mutations in a tumor panel representative of pilocytic astrocytoma diversity using a p53 functional assay.

6 July 2018

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Genomic targeting with an MBP-Cre fusion protein

6 July 2018

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6 July 2018

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Up-regulation of specific NF 1 gene transcripts in sporadic pilocytic astrocytomas.

6 July 2018

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Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues

6 July 2018

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Tumour predisposition in mice heterozygous for a targeted mutation in Nf1

6 July 2018

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Site-specific recombination mediated by an adenovirus vector expressing the Cre recombinase protein: a molecular switch for control of gene expression

6 July 2018

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Neurofibromin expression and astrogliosis in neurofibromatosis (type 1) brains.

6 July 2018

1 reference

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Type 1 neurofibromatosis gene: identification of a large transcript disrupted in three NF1 patients

6 July 2018

1 reference

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The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins

6 July 2018

1 reference

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6 July 2018

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The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S. cerevisiae

6 July 2018

1 reference

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A major segment of the neurofibromatosis type 1 gene: cDNA sequence, genomic structure, and point mutations

6 July 2018

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Identification of the neurofibromatosis type 1 gene product

6 July 2018

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Deletions and a translocation interrupt a cloned gene at the neurofibromatosis type 1 locus.

6 July 2018

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Regulators and Effectors of ras Proteins

6 July 2018

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Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients

6 July 2018

1 reference

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Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis

6 July 2018

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Uptake of [3H]serotonin and [3H]glutamate by primary astrocyte cultures. II. Differences in cultures prepared from different brain regions

6 July 2018

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Comparative gene expression profile analysis of neurofibromatosis 1-associated and sporadic pilocytic astrocytomas.

6 July 2018

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Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease.

27 October 2018

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Loss of NF1 alleles distinguish sporadic from NF1-associated pilocytic astrocytomas.

27 October 2018

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Astrocyte-specific expression of activated p21-ras results in malignant astrocytoma formation in a transgenic mouse model of human gliomas.

27 October 2018

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Pilocytic astrocytomas do not show most of the genetic changes commonly seen in diffuse astrocytomas.

27 October 2018

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Loss of neurofibromin is associated with activation of RAS/MAPK and PI3-K/AKT signaling in a neurofibromatosis 1 astrocytoma.

27 October 2018

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Loss of neurofibromatosis 1 (NF1) gene expression in NF1-associated pilocytic astrocytomas.

27 October 2018

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Z/AP, a double reporter for cre-mediated recombination.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139771

Optic pathway gliomas in children with neurofibromatosis 1: consensus statement from the NF1 Optic Pathway Glioma Task Force.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139771

Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139771

Differential expression and tissue distribution of type I and type II neurofibromins during mouse fetal development.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139771

Nonrandom chromosomal gains in pilocytic astrocytomas of childhood.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139771

Distinctive growth patterns between cerebral and cerebellar astrocytomas--a tissue culture study.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139771

Expression of the neurofibromatosis 1 (NF1) gene during growth arrest

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12077339

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Efficient liver-specific deletion of a floxed human angiotensinogen transgene by adenoviral delivery of Cre recombinase in vivo

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12077339

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Astrocytes exhibit regional specificity in gap-junction coupling

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12077339

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.22.14.5100-5113.2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12077339%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12077339%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference