The role of molecular forms of prostate-specific antigen (PSA or hK3) and of human glandular kallikrein 2 (hK2) in the diagnosis and monitoring of prostate cancer and in extra-prostatic disease. (Q34447102)

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English	The role of molecular forms of prostate-specific antigen (PSA or hK3) and of human glandular kallikrein 2 (hK2) in the diagnosis and monitoring of prostate cancer and in extra-prostatic disease.	scientific article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11720279%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

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Europe PubMed Central

The role of molecular forms of prostate-specific antigen (PSA or hK3) and of human glandular kallikrein 2 (hK2) in the diagnosis and monitoring of prostate cancer and in extra-prostatic disease (English)

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Europe PubMed Central

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3 December 2019

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3 December 2019

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C Becker

1

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3 December 2019

J Noldus

2

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3 December 2019

E Diamandis

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3 December 2019

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1 October 2001

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3 December 2019

Critical Reviews in Clinical Laboratory Sciences

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3 December 2019

38

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3 December 2019

5

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3 December 2019

357-399

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3 December 2019

Primary structure of a human glandular kallikrein gene

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Characterization of the prostate-specific antigen gene: a novel human kallikrein-like gene

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

The prostate-specific antigen gene and the human glandular kallikrein-1 gene are tandemly located on chromosome 19.

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Characterization of the human kallikrein locus

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Nucleotide sequence of cloned cDNA for human pancreatic kallikrein

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

The glandular kallikrein family of enzymes: tissue-specific expression and hormonal regulation

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Expression of the gene coding for human prostate-specific antigen and related hGK-1 in benign and malignant tumors of the human prostate

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Tissue-specific and hormonal regulation of human prostate-specific glandular kallikrein

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

The new human kallikrein gene family: implications in carcinogenesis

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Molecular cloning of the human kallikrein 15 gene (KLK15). Up-regulation in prostate cancer

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Molecular cloning of human prostate specific antigen cDNA.

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Sequence of a cDNA clone encompassing the complete mature human prostate specific antigen (PSA) and an unspliced leader sequence

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Molecular mass and carbohydrate structure of prostate specific antigen: studies for establishment of an international PSA standard.

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Activation of the zymogen form of prostate-specific antigen by human glandular kallikrein 2.

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Characterization of the precursor of prostate-specific antigen. Activation by trypsin and by human glandular kallikrein.

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Activation of prostate-specific antigen precursor (pro-PSA) by prostin, a novel human prostatic serine protease identified by degenerate PCR

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

The chymotrypsin-like activity of human prostate-specific antigen, gamma-seminoprotein

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Enzymatic activity of prostate-specific antigen and its reactions with extracellular serine proteinase inhibitors

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Three predominant proteins secreted by the human prostate gland

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Characterization of the predominant basic protein in human seminal plasma, one cleavage product of the major seminal vesicle protein

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

A kallikrein-like serine protease in prostatic fluid cleaves the predominant seminal vesicle protein

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Seminal vesicle-secreted proteins and their reactions during gelation and liquefaction of human semen

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Human seminal vesicle-specific antigen during semen liquefaction

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Human seminal vesicle-specific antigen is a substrate for prostate-specific antigen (or P-30).

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Antiangiogenic activity of prostate-specific antigen

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Complex formation between protein C inhibitor and prostate-specific antigen in vitro and in human semen

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Human prostate-specific antigen: structural and functional similarity with serine proteases

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

A precursor form of PSA (pPSA) is a component of the free PSA in prostate cancer serum

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Organ distribution in rats of two members of the low-density lipoprotein receptor gene family, gp330 and LRP/alpha 2MR, and the receptor-associated protein (RAP)

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Differential recognition of alpha 1-antitrypsin-elastase and alpha 1-antichymotrypsin-cathepsin G complexes by the low density lipoprotein receptor-related protein

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Prostate cancer detection in men with serum PSA concentrations of 2.6 to 4.0 ng/mL and benign prostate examination. Enhancement of specificity with free PSA measurements

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Serum prostate-specific antigen in a community-based population of healthy men. Establishment of age-specific reference ranges

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Age specific prostate specific antigen reference ranges: population specific

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Longitudinal evaluation of prostate-specific antigen levels in men with and without prostate disease

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Evaluation of percentage of free serum prostate-specific antigen to improve specificity of prostate cancer screening

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Measurement of the proportion of free to total prostate-specific antigen improves diagnostic performance of prostate-specific antigen in the diagnostic gray zone of total prostate-specific antigen

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Use of percentage of free prostate-specific antigen to identify men at high risk of prostate cancer when PSA levels are 2.51 to 4 ng/mL and digital rectal examination is not suspicious for prostate cancer: an alternative model

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Use of human glandular kallikrein 2 for the detection of prostate cancer: preliminary analysis

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Diagnostic value of percent free prostate-specific antigen: retrospective analysis of a population-based screening study with emphasis on men with PSA levels less than 3.0 ng/mL.

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Percent free prostate specific antigen and cancer detection in black and white men with total prostate specific antigen 2.5 to 9.9 ng./ml

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Use of the percentage of free prostate-specific antigen to enhance differentiation of prostate cancer from benign prostatic disease: a prospective multicenter clinical trial

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

The value of screening tests in the detection of prostate cancer. Part II: Retrospective analysis of free/total prostate-specific analysis ratio, age-specific reference ranges, and PSA density

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Usefulness of the ratio free/total prostate-specific antigen in addition to total PSA levels in prostate cancer screening

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Prospective use of free prostate-specific antigen to avoid repeat prostate biopsies in men with elevated total prostate-specific antigen

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Prediction of post-radical prostatectomy pathological outcome for stage T1c prostate cancer with percent free prostate specific antigen: a prospective multicenter clinical trial

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Elevated serum prostate-specific antigen due to acute bacterial prostatitis.

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Stability of free prostate-specific antigen in serum samples under a variety of sample collection and sample storage conditions

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Two-year stability of free and total PSA in frozen serum samples

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Measurement of complexed PSA improves specificity for early detection of prostate cancer

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Prostatic manipulation has a minimal effect on complexed prostate-specific antigen levels

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

A multicenter clinical trial on the use of alpha1-antichymotrypsin-prostate-specific antigen in prostate cancer diagnosis.

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Complexed prostate specific antigen provides significant enhancement of specificity compared with total prostate specific antigen for detecting prostate cancer

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Comparison of two investigative assays for the complexed prostate-specific antigen in total prostate-specific antigen between 4.1 and 10.0 ng/mL.

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Human glandular kallikrein 2 (hK2) expression in prostatic intraepithelial neoplasia and adenocarcinoma: a novel prostate cancer marker

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Detection of a prostate-specific protein, human glandular kallikrein (hK2), in sera of patients with elevated prostate-specific antigen levels

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Development of monoclonal antibodies specific for human glandular kallikrein (hK2): development of a dual antibody immunoassay for hK2 with negligible prostate-specific antigen cross-reactivity

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Clinical value of human glandular kallikrein 2 and free and total prostate-specific antigen in serum from a population of men with prostate-specific antigen levels 3.0 ng/mL or greater

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Serum human glandular kallikrein-2 protease levels predict the presence of prostate cancer among men with elevated prostate-specific antigen

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Human glandular kallikrein, hK2, shows arginine-restricted specificity and forms complexes with plasma protease inhibitors

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Ala217 is important for the catalytic function and autoactivation of prostate-specific human kallikrein 2.

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Production and activation of recombinant hK2 with propeptide mutations resulting in high expression levels

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Enzymatic action of human glandular kallikrein 2 (hK2). Substrate specificity and regulation by Zn2+ and extracellular protease inhibitors

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Prostatic human kallikrein 2 inactivates and complexes with plasminogen activator inhibitor-1.

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Overexpression of a human prostate-specific glandular kallikrein, hK2, in E. coli and generation of antibodies

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Immunoreactivity of recombinant human glandular kallikrein using monoclonal antibodies raised against prostate-specific antigen.

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Polyclonal and monoclonal antibodies to prostate-specific antigen can cross-react with human kallikrein 2 and human kallikrein 1.

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Human glandular kallikrein 2: a potential serum marker for predicting the organ confined versus non-organ confined growth of prostate cancer.

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Frequency of expression of prostate-specific antigen mRNA in lung tumors

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Immunohistochemical identification ofprostatic acid phosphatase and prostate specific antigen in female periurethral glands

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Primary adenocarcinoma of the urinary bladder. A clinicopathologic analysis of 72 cases

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Extraprostatic localization of prostatic acid phosphatase and prostate-specific antigen: distribution in cloacogenic glandular epithelium and sex-dependent expression in human anal gland

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Immunohistochemical localization of prostate-specific markers within the accessory male sex glands of Cowper, Littre, and Morgagni

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Human Kallikrein 2 (hK2) and prostate-specific antigen (PSA): two closely related, but distinct, kallikreins in the prostate

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Dramatic suppression of plasma and urinary prostate specific antigen and human glandular kallikrein by antiandrogens in male-to-female transsexuals

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

The diagnostic and prognostic utility of prostate-specific antigen for diseases of the breast.

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Expression of a prostate-associated protein, human glandular kallikrein (hK2), in breast tumours and in normal breast secretions

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Induction of prostate specific antigen production by steroids and tamoxifen in breast cancer cell lines

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Steroid hormone regulation of prostate-specific antigen gene expression in breast cancer

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Differential steroid hormone regulation of human glandular kallikrein (hK2) and prostate-specific antigen (PSA) in breast cancer cell lines

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

An androgen response element in a far upstream enhancer region is essential for high, androgen-regulated activity of the prostate-specific antigen promoter

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Immunohistochemical localization of prostate-specific antigen in benign and malignant breast tissues

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Prostate-specific antigen and gross cystic disease fluid protein-15 are co-expressed in androgen receptor-positive breast tumours

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

The promoter and the enhancer region of the KLK 3 (prostate specific antigen) gene is frequently mutated in breast tumours and in breast carcinoma cell lines

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Expression of prostate-specific antigen (PSA) correlates with poor response to tamoxifen therapy in recurrent breast cancer

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Prostate-specific antigen induction by a steroid hormone in T47D cells growing in SCID mice

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Prostate-specific antigen in breast cyst fluid: possible role of prostate-specific antigen in hormone-dependent breast cancer

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Prostate-specific antigen in amniotic fluid of normal and abnormal pregnancies.

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Molecular forms of prostate-specific antigen in the serum of women with benign and malignant breast diseases

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

The increased circulating prostate-specific antigen concentrations in women with hirsutism do not respond to acute changes in adrenal or ovarian function

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Reverse transcriptase-polymerase chain reaction for prostate-specific antigen may be a prognostic indicator in breast cancer

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Prostate specific antigen — a new constituent of breast cyst fluid

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Free, complexed and total serum prostate-specific antigen concentrations and their proportions in predicting stage, grade and deoxyribonucleic acid ploidy in patients with adenocarcinoma of the prostate

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Expression of prostate-specific antigen and human glandular kallikrein 2 in the thyroid gland

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Immunoreactive prostate-specific antigen levels in female and male breast tumors and its association with steroid hormone receptors and patient age

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Detection of prostate-specific antigen immunoreactivity in breast tumors

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Oral Contraceptive-induced Expression of Prostate-specific Antigen in the Female Breast

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Prostate-Specific antigen expression by various tumors

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Immunoreactive prostate-specific antigen in lung tumors

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Original Articles: Prostate Cancer: Measurement of Serum Prostate Specific Antigen Levels in Women and in Prostatectomized Men With an Ultrasensitive Immunoassay Technique

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

Elevated Serum Prostate-Specific Antigen Levels in a Woman with Metastatic Breast Cancer

1 reference

https://api.crossref.org/works/10.1080%2F20014091084236

21 January 2018

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