STAM/EAST/Hbp adapter proteins--integrators of signalling pathways. (Q34453127)

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4 December 2019

review article

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title

STAM/EAST/Hbp adapter proteins--integrators of signalling pathways (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11728436%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

1

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4 December 2019

author name string

V P Lehto

series ordinal

2

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4 December 2019

language of work or name

English

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publication date

1 November 2001

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4 December 2019

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4 December 2019

volume

508

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4 December 2019

issue

3

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4 December 2019

page(s)

287-290

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Cloning of a novel signal-transducing adaptor molecule containing an SH3 domain and ITAM

4 December 2019

cites work

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EAST, an epidermal growth factor receptor- and Eps15-associated protein with Src homology 3 and tyrosine-based activation motif domains

21 January 2018

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A hrs binding protein having a Src homology 3 domain is involved in intracellular degradation of growth factors and their receptors

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VHS domain marks a group of proteins involved in endocytosis and vesicular trafficking

21 January 2018

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Crystal structure of the VHS and FYVE tandem domains of Hrs, a protein involved in membrane trafficking and signal transduction

21 January 2018

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Structure of the VHS domain of human Tom1 (target of myb 1): insights into interactions with proteins and membranes

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A ubiquitin-interacting motif conserved in components of the proteasomal and lysosomal protein degradation systems

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Hrs is associated with STAM, a signal-transducing adaptor molecule. Its suppressive effect on cytokine-induced cell growth

21 January 2018

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STAM2, a new member of the STAM family, binding to the Janus kinases

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Loss of hippocampal CA3 pyramidal neurons in mice lacking STAM1.

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The Drosophila STAM gene homolog is in a tight gene cluster, and its expression correlates to that of the adjacent gene ial.

21 January 2018

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EAST, a novel EGF receptor substrate, associates with focal adhesions and actin fibers

21 January 2018

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Identification of a novel immunoreceptor tyrosine-based activation motif-containing molecule, STAM2, by mass spectrometry and its involvement in growth factor and cytokine receptor signaling pathways

21 January 2018

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STAM, signal transducing adaptor molecule, is associated with Janus kinases and involved in signaling for cell growth and c-myc induction

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Src phosphorylates EAST, a novel EGF receptor-associated protein.

21 January 2018

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Possible involvement of a novel STAM-associated molecule "AMSH" in intracellular signal transduction mediated by cytokines

21 January 2018

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Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads

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Function of Hrs in endocytic trafficking and signalling

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Hrs recruits clathrin to early endosomes

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Hrs-2 regulates receptor-mediated endocytosis via interactions with Eps15

21 January 2018

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Hrs interacts with sorting nexin 1 and regulates degradation of epidermal growth factor receptor

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A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

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Interleukin 2 receptors and detergent-resistant membrane domains define a clathrin-independent endocytic pathway

21 January 2018

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Involvement of hrs binding protein in IgE receptor-triggered exocytosis in RBL-2H3 mast cells

21 January 2018

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A deubiquitinating enzyme UBPY interacts with the Src homology 3 domain of Hrs-binding protein via a novel binding motif PX(V/I)(D/N)RXXKP

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Molecular links between endocytosis and the actin cytoskeleton.

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21 January 2018

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21 January 2018

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Yeast Eps15-like endocytic protein, Pan1p, activates the Arp2/3 complex

21 January 2018

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10.1016/S0014-5793(01)03079-4

7 January 2021

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11728436%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

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