LAMTOR2 regulates dendritic cell homeostasis through FLT3-dependent mTOR signalling (Q34453798)

2 August 2017

LAMTOR2 regulates dendritic cell homeostasis through FLT3-dependent mTOR signalling (English)

1 reference

2 August 2017

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25336251%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Nikolaus Romani

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25336251%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Patrizia Stoitzner

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25336251%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Lukas Alfons Huber

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25336251%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

author name string

Julia M Scheffler

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25336251%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Florian Sparber

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25336251%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Caroline Herrmann

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25336251%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Alexandra Humenberger

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25336251%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Johanna Blitz

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25336251%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

language of work or name

English

0 references

publication date

22 October 2014

1 reference

2 August 2017

Nature Communications

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25336251%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25336251%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

page(s)

5138

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25336251%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

6 June 2020

copyright license

start time

22 October 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/ncomms6138

0 references

cites work

Where is mTOR and what is it doing there?

1 reference

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The late endosomal adaptor molecule p14 (LAMTOR2) represents a novel regulator of Langerhans cell homeostasis

6 July 2018

1 reference

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Stability of the endosomal scaffold protein LAMTOR3 depends on heterodimer assembly and proteasomal degradation.

6 July 2018

1 reference

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The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting

6 July 2018

1 reference

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Nutrient signaling to mTOR and cell growth

6 July 2018

1 reference

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Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1

6 July 2018

1 reference

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GM-CSF controls nonlymphoid tissue dendritic cell homeostasis but is dispensable for the differentiation of inflammatory dendritic cells

6 July 2018

1 reference

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Decisions about dendritic cells: past, present, and future

6 July 2018

1 reference

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Mammalian target of rapamycin controls dendritic cell development downstream of Flt3 ligand signaling

6 July 2018

1 reference

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Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

6 July 2018

1 reference

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Instructive cytokine signals in dendritic cell lineage commitment

6 July 2018

1 reference

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AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML)

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4220488

The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK-ERK pathway to late endosomes.

6 July 2018

1 reference

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Dendritic cell homeostasis

6 July 2018

1 reference

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The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues

6 July 2018

1 reference

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Notch-RBP-J signaling controls the homeostasis of CD8- dendritic cells in the spleen.

6 July 2018

1 reference

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p14-MP1-MEK1 signaling regulates endosomal traffic and cellular proliferation during tissue homeostasis

6 July 2018

1 reference

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The MEK1 scaffolding protein MP1 regulates cell spreading by integrating PAK1 and Rho signals.

6 July 2018

1 reference

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Cell biology of antigen processing in vitro and in vivo

6 July 2018

1 reference

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Crystal structure of the p14/MP1 scaffolding complex: how a twin couple attaches mitogen-activated protein kinase signaling to late endosomes

6 July 2018

1 reference

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The odd couple: signal transduction and endocytosis

6 July 2018

1 reference

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Rapamycin inhibits IL-4--induced dendritic cell maturation in vitro and dendritic cell mobilization and function in vivo

6 July 2018

1 reference

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Localization of the MP1-MAPK scaffold complex to endosomes is mediated by p14 and required for signal transduction

6 July 2018

1 reference

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FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model

6 July 2018

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Role of hematopoietic growth factors/flt3 ligand in expansion and regulation of dendritic cells

6 July 2018

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A novel 14-kilodalton protein interacts with the mitogen-activated protein kinase scaffold mp1 on a late endosomal/lysosomal compartment

6 July 2018

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Cell-surface trafficking and release of flt3 ligand from T lymphocytes is induced by common cytokine receptor gamma-chain signaling and inhibited by cyclosporin A

6 July 2018

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Chronic expression of murine flt3 ligand in mice results in increased circulating white blood cell levels and abnormal cellular infiltrates associated with splenic fibrosis.

6 July 2018

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Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: multiple dendritic cell subpopulations identified

6 July 2018

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Biochemical and genetic characterization of multiple splice variants of the Flt3 ligand

6 July 2018

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Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha

6 July 2018

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Proliferating dendritic cell progenitors in human blood

6 July 2018

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Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor

6 July 2018

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Interactions between kinase scaffold MP1/p14 and its endosomal anchoring protein p18.

6 July 2018

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A novel human primary immunodeficiency syndrome caused by deficiency of the endosomal adaptor protein p14.

21 January 2018

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The late endosomal adaptor p14 is a macrophage host-defense factor against Salmonella infection.

21 January 2018

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The influence of granulocyte/macrophage colony-stimulating factor on dendritic cell levels in mouse lymphoid organs.

21 January 2018

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Development of plasmacytoid and conventional dendritic cell subtypes from single precursor cells derived in vitro and in vivo.

21 January 2018

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Cutting edge: generation of splenic CD8+ and CD8- dendritic cell equivalents in Fms-like tyrosine kinase 3 ligand bone marrow cultures.

21 January 2018

1 reference

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Flt3 inhibitor AC220 is a potent therapy in a mouse model of myeloproliferative disease driven by enhanced wild-type Flt3 signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6138

Lack of conventional dendritic cells is compatible with normal development and T cell homeostasis, but causes myeloid proliferative syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6138

STAT3 is required for Flt3L-dependent dendritic cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6138

Hematologic effects of flt3 ligand in vivo in mice

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25336251

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCOMMS6138

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25336251%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

6 June 2020

ADS bibcode

2014NatCo...5.5138S

0 references

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25336251%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25336251%20AND%20SRC:MED&resulttype=core&format=json