A maladaptive role for EP4 receptors in podocytes (Q34455476)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20671216%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

title

A maladaptive role for EP4 receptors in podocytes (English)

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8 February 2020

2

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8 February 2020

author name string

Erin M Stitt-Cavanagh

1

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8 February 2020

Kaede Takami

3

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8 February 2020

Anthony Carter

4

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8 February 2020

Barbara Vanderhyden

5

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8 February 2020

Youfei Guan

6

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8 February 2020

Andre Schneider

7

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8 February 2020

Matthew D Breyer

8

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8 February 2020

Christopher R J Kennedy

9

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8 February 2020

publication date

29 July 2010

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Journal of the American Society of Nephrology

8 February 2020

published in

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8 February 2020

volume

21

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8 February 2020

page(s)

1678-1690

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8 February 2020

issue

10

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Distinct roles for basal and induced COX-2 in podocyte injury

8 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

Glomerular type 1 angiotensin receptors augment kidney injury and inflammation in murine autoimmune nephritis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

Gq-dependent signaling upregulates COX2 in glomerular podocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

Pathogenesis of the podocytopathy and proteinuria in diabetic glomerulopathy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

Rho GTPase and cAMP/protein kinase A signaling mediates myocilin-induced alterations in cultured human trabecular meshwork cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

The podocyte's response to injury: role in proteinuria and glomerulosclerosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

From the periphery of the glomerular capillary wall toward the center of disease: podocyte injury comes of age in diabetic nephropathy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

In response to protein load podocytes reorganize cytoskeleton and modulate endothelin-1 gene: implication for permselective dysfunction of chronic nephropathies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

Pathways to nephron loss starting from glomerular diseases-insights from animal models

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

Angiotensin II type 1 receptor overexpression in podocytes induces glomerulosclerosis in transgenic rats

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

Activation of a local tissue angiotensin system in podocytes by mechanical strain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

p38 MAP kinase mediates mechanically induced COX-2 and PG EP4 receptor expression in podocytes: implications for the actin cytoskeleton

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

Causes and consequences of proteinuria: the kidney filtration barrier and progressive renal failure

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

Podocyte biology and the emerging understanding of podocyte diseases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

Serine phosphorylation negatively regulates RhoA in vivo.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

Podocyte is the major culprit accounting for the progression of chronic renal disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

Sequestration and phosphorylation of the prostaglandin E2 EP4 receptor: dependence on the C-terminal tail.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

Prostanoid receptors: subtypes and signaling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

Generalized lacZ expression with the ROSA26 Cre reporter strain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

Molecular cloning and characterization of the four rat prostaglandin E2 prostanoid receptor subtypes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

Rearrangements of the cytoskeleton and cell contacts induce process formation during differentiation of conditionally immortalized mouse podocyte cell lines.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

Disruption of overlapping transcripts in the ROSA beta geo 26 gene trap strain leads to widespread expression of beta-galactosidase in mouse embryos and hematopoietic cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

Renal toxicity of the nonsteroidal anti-inflammatory drugs

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

Effects of nonsteroidal anti-inflammatory drugs on proteinuria

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

The podocyte in diabetic kidney disease.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

PGE(2) induces COX-2 expression in podocytes via the EP(4) receptor through a PKA-independent mechanism

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

Overexpression of cyclooxygenase-2 predisposes to podocyte injury.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

Prostaglandin E2 promotes cell survival of glomerular epithelial cells via the EP4 receptor

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

Activation of Galpha q-coupled signaling pathways in glomerular podocytes promotes renal injury

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

Characterization of susceptibility of inbred mouse strains to diabetic nephropathy.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

Regulation of renal lipid metabolism, lipid accumulation, and glomerulosclerosis in FVBdb/db mice with type 2 diabetes

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

Reduction in albuminuria translates to reduction in cardiovascular events in hypertensive patients: losartan intervention for endpoint reduction in hypertension study

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

Generation of a conditional allele of the mouse prostaglandin EP4 receptor.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

Model of robust induction of glomerulosclerosis in mice: importance of genetic background.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

Evaluation of a new tool for exploring podocyte biology: mouse Nphs1 5' flanking region drives LacZ expression in podocytes.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013547

Role of EP2 and EP4 receptor-selective agonists of prostaglandin E(2) in acute and chronic kidney failure

27 October 2018

1 reference

12 December 2020

Puromycin induces reversible proteinuric injury in transgenic mice expressing cyclooxygenase-2 in podocytes

1 reference

12 December 2020

Podocyte loss in aging OVE26 diabetic mice

1 reference

12 December 2020

A selective cyclooxygenase-2 inhibitor decreases proteinuria and retards progressive renal injury in rats

1 reference

12 December 2020

Podocytes respond to mechanical stress in vitro

1 reference

12 December 2020

Focal and segmental glomerulosclerosis in mice with podocyte-specific expression of mutant alpha-actinin-4

1 reference

12 December 2020

Benefits and risks of nonsteroidal antiinflammatory drugs in steroid-resistant nephrotic syndrome

1 reference

12 December 2020

Selective increase of cyclooxygenase-2 expression in a model of renal ablation

1 reference

12 December 2020

Complement (C5b-9) induces glomerular epithelial cell DNA synthesis but not proliferation in vitro

1 reference

12 December 2020

Characterization of prostanoid receptors in podocytes

1 reference

12 December 2020

Identifiers

DOI

10.1681/ASN.2009121234

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20671216%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20671216%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference