mTOR inhibition improves immune function in the elderly (Q34455680)

2 August 2017

mTOR inhibition improves immune function in the elderly (English)

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2 August 2017

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8

Holden T Maecker

1 reference

2 August 2017

Joan B Mannick

1

1 reference

2 August 2017

Giuseppe Del Giudice

2

1 reference

2 August 2017

Maria Lattanzi

3

1 reference

2 August 2017

Nicholas M Valiante

4

1 reference

2 August 2017

Jens Praestgaard

5

1 reference

2 August 2017

Baisong Huang

6

1 reference

2 August 2017

Michael A Lonetto

7

1 reference

2 August 2017

John Kovarik

9

1 reference

2 August 2017

Simon Carson

10

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2 August 2017

David J Glass

11

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2 August 2017

Lloyd B Klickstein

12

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2 August 2017

language of work or name

English

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publication date

1 December 2014

1 reference

Science Translational Medicine

2 August 2017

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2 August 2017

6

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2 August 2017

268ra179

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2 August 2017

268

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Preserving youth: does rapamycin deliver?

2 August 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3009892

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3009892

Rapamycin slows aging in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3009892

Late-life rapamycin treatment reverses age-related heart dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3009892

Mortality associated with influenza and respiratory syncytial virus in the United States

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3009892

Antibody response to influenza vaccination in the elderly: a quantitative review

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3009892

The gracefully aging immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3009892

Partial restoration of T-cell function in aged mice by in vitro blockade of the PD-1/ PD-L1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3009892

PD-1+ memory phenotype CD4+ T cells expressing C/EBPalpha underlie T cell immunodepression in senescence and leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3009892

mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3009892

Evidence of increased clinical protection of an MF59-adjuvant influenza vaccine compared to a non-adjuvant vaccine among elderly residents of long-term care facilities in Italy

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3009892

Identifying optimal biologic doses of everolimus (RAD001) in patients with cancer based on the modeling of preclinical and clinical pharmacokinetic and pharmacodynamic data

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3009892

The kinase mTOR modulates the antibody response to provide cross-protective immunity to lethal infection with influenza virus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3009892

NFATc1 regulates PD-1 expression upon T cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3009892

mTOR regulates memory CD8 T-cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3009892

Viral acute lower respiratory infections impair CD8+ T cells through PD-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3009892

The adjuvanted influenza vaccines with novel adjuvants: experience with the MF59-adjuvanted vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3009892

Cutting edge: Rapamycin augments pathogen-specific but not graft-reactive CD8+ T cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3009892

Molecular analyses provide insight into mechanisms underlying sarcopenia and myofibre denervation in old skeletal muscles of mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3009892

Human circulating influenza-CD4+ ICOS1+IL-21+ T cells expand after vaccination, exert helper function, and predict antibody responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3009892

Stratified false discovery control for large-scale hypothesis testing with application to genome-wide association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3009892

10.1126/SCITRANSLMED.3009892

21 January 2018

Identifiers

DOI

1 reference

2 August 2017

1 reference