Sustained beta-cell dysfunction but normalized islet mass in aged thrombospondin-1 deficient mice. (Q34456321)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23094049%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

title

Sustained beta-cell dysfunction but normalized islet mass in aged thrombospondin-1 deficient mice (English)

1 reference

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16 February 2020

author

Gustaf Christoffersson

4

1 reference

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16 February 2020

author name string

Carl Johan Drott

1

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16 February 2020

Johan Olerud

2

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16 February 2020

Hanna Emanuelsson

3

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16 February 2020

Per-Ola Carlsson

5

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16 February 2020

language of work or name

English

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publication date

19 October 2012

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16 February 2020

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16 February 2020

volume

7

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16 February 2020

issue

10

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16 February 2020

page(s)

e47451

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Creative Commons Attribution 4.0 International

16 February 2020

copyright license

start time

19 October 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3477147/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Thrombospondin-1: an islet endothelial cell signal of importance for β-cell function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477147

Improved vascular engraftment and graft function after inhibition of the angiostatic factor thrombospondin-1 in mouse pancreatic islets

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477147

The vascular basement membrane: a niche for insulin gene expression and Beta cell proliferation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477147

Donor islet endothelial cells participate in formation of functional vessels within pancreatic islet grafts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477147

Low revascularization of experimentally transplanted human pancreatic islets

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477147

Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477147

TGF-beta plays a key role in morphogenesis of the pancreatic islets of Langerhans by controlling the activity of the matrix metalloproteinase MMP-2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477147

Thrombospondin-1 is a major activator of TGF-beta1 in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477147

Accumulation of extracellular matrix and developmental dysregulation in the pancreas by transgenic production of transforming growth factor-beta 1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477147

Morphological evidence for pancreatic polarity of beta-cell within islets of Langerhans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477147

Hyperglycemia-induced B cell toxicity. The fate of pancreatic islets transplanted into diabetic mice is dependent on their genetic background

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477147

TGF-beta stimulates insulin secretion and blocks mitogenic response of pancreatic beta-cells to glucose

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477147

A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477147

Isolated mouse pancreatic islets in culture: Effects of serum and different culture media on the insulin production of the islets

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477147

Control of pancreatic β cell regeneration by glucose metabolism.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477147

Endothelial cell signalling supports pancreatic beta cell function in the rat.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477147

Limited capacity of human adult islets expanded in vitro to redifferentiate into insulin-producing beta-cells

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477147

Pancreatic islet production of vascular endothelial growth factor--a is essential for islet vascularization, revascularization, and function.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477147

Perinatal development of the pancreatic islet microvasculature in rats

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477147

Islet endothelial cells and pancreatic beta-cell proliferation: studies in vitro and during pregnancy in adult rats.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477147

VEGF-dependent plasticity of fenestrated capillaries in the normal adult microvasculature

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477147

Role of VEGF-A in vascularization of pancreatic islets

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477147

Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1

27 October 2018

1 reference

12 December 2020

Decreased vascular density in mouse pancreatic islets after transplantation

1 reference

12 December 2020

Histological markers for endothelial cells in endogenous and transplanted rodent pancreatic islets

1 reference

12 December 2020

A rapid method of visualizing the pancreatic islets for studies of islet capillary blood flow using non-radioactive microspheres

1 reference

12 December 2020

Pancreatic islet blood flow in normal and obese-hyperglycemic (ob/ob) mice

1 reference

12 December 2020

Influence of age, hyperglycemia, leptin, and NPY on islet blood flow in obese-hyperglycemic mice

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0047451

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23094049%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23094049%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23094049%20AND%20SRC:MED&resulttype=core&format=json