Multiple innate immune pathways contribute to the immunogenicity of recombinant adenovirus vaccine vectors (Q34457800)

2 August 2017

title

Multiple innate immune pathways contribute to the immunogenicity of recombinant adenovirus vaccine vectors (English)

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2 August 2017

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8

Nathaniel L Simmons

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2 August 2017

12

Dan H Barouch

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2 August 2017

10

Bali Pulendran

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2 August 2017

3

Sudhir P Kasturi

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2 August 2017

Elizabeth G Rhee

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2 August 2017

Joseph N Blattman

2

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2 August 2017

R Phelps Kelley

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2 August 2017

David R Kaufman

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2 August 2017

Diana M Lynch

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2 August 2017

Annalena La Porte

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2 August 2017

Sarah L Clark

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2 August 2017

Philip D Greenberg

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2 August 2017

language of work or name

English

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publication date

20 October 2010

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2 August 2017

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2 August 2017

volume

85

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2 August 2017

issue

1

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2 August 2017

page(s)

315-323

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Route of adenovirus-based HIV-1 vaccine delivery impacts the phenotype and trafficking of vaccine-elicited CD8+ T lymphocytes.

2 August 2017

cites work

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6 July 2018

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6 July 2018

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6 July 2018

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Key role of splenic myeloid DCs in the IFN-alphabeta response to adenoviruses in vivo

6 July 2018

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IL-1, IL-18, and IL-33 families of cytokines

6 July 2018

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The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response

6 July 2018

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Adenovirus vector induced innate immune responses: impact upon efficacy and toxicity in gene therapy and vaccine applications

6 July 2018

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Comparative seroprevalence and immunogenicity of six rare serotype recombinant adenovirus vaccine vectors from subgroups B and D

6 July 2018

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Sensing infection by adenovirus: Toll-like receptor-independent viral DNA recognition signals activation of the interferon regulatory factor 3 master regulator

6 July 2018

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Innate immune response to adenoviral vectors is mediated by both Toll-like receptor-dependent and -independent pathways

6 July 2018

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Adenovirus infection triggers a rapid, MyD88-regulated transcriptome response critical to acute-phase and adaptive immune responses in vivo

6 July 2018

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Modulation of DNA vaccine-elicited CD8+ T-lymphocyte epitope immunodominance hierarchies

6 July 2018

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Adenovirus efficiently transduces plasmacytoid dendritic cells resulting in TLR9-dependent maturation and IFN-alpha production

6 July 2018

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Translating innate immunity into immunological memory: implications for vaccine development

6 July 2018

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Pathogen recognition and innate immunity

6 July 2018

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Yellow fever vaccine YF-17D activates multiple dendritic cell subsets via TLR2, 7, 8, and 9 to stimulate polyvalent immunity

6 July 2018

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Immunogenicity of recombinant fiber-chimeric adenovirus serotype 35 vector-based vaccines in mice and rhesus monkeys

6 July 2018

1 reference

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Toll-like receptor control of the adaptive immune responses

6 July 2018

1 reference

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Replication-deficient human adenovirus type 35 vectors for gene transfer and vaccination: efficient human cell infection and bypass of preexisting adenovirus immunity

6 July 2018

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6 July 2018

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Differential activation of innate immune responses by adenovirus and adeno-associated virus vectors

6 July 2018

1 reference

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Activation of innate immunity in nonhuman primates following intraportal administration of adenoviral vectors.

6 July 2018

1 reference

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Adenoviral gene therapy leads to rapid induction of multiple chemokines and acute neutrophil-dependent hepatic injury in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3014160

Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3014160

The role of Kupffer cell activation and viral gene expression in early liver toxicity after infusion of recombinant adenovirus vectors.

6 July 2018

1 reference

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Phenotypic analysis of antigen-specific T lymphocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3014160

Virus binding to a plasma membrane receptor triggers interleukin-1 alpha-mediated proinflammatory macrophage response in vivo

6 July 2018

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Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys

27 October 2018

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Trafficking of antigen-specific CD8+ T lymphocytes to mucosal surfaces following intramuscular vaccination

27 October 2018

1 reference

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Magnitude and phenotype of cellular immune responses elicited by recombinant adenovirus vectors and heterologous prime-boost regimens in rhesus monkeys

27 October 2018

1 reference

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Role of MyD88 and TLR9 in the innate immune response elicited by serotype 5 adenoviral vectors

27 October 2018

1 reference

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Hexon-chimaeric adenovirus serotype 5 vectors circumvent pre-existing anti-vector immunity

27 October 2018

1 reference

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Interference with the IL-1-signaling pathway improves the toxicity profile of systemically applied adenovirus vectors

27 October 2018

1 reference

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Immunogenicity of recombinant adenovirus serotype 35 vaccine in the presence of pre-existing anti-Ad5 immunity

27 October 2018

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Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunity

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3014160

Adenovirus vector-induced innate inflammatory mediators, MAPK signaling, as well as adaptive immune responses are dependent upon both TLR2 and TLR9 in vivo

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20962088

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

1 reference

https://pubmed.ncbi.nlm.nih.gov/20962088

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/JVI.01597-10

1 reference

2 August 2017

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2 August 2017

1 reference