Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase- and cathepsin-dependent emphysema (Q34457903)

2 August 2017

Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase- and cathepsin-dependent emphysema (English)

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2 August 2017

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T Zheng

1

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2 August 2017

Z Zhu

2

1 reference

2 August 2017

Z Wang

3

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2 August 2017

R J Homer

4

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2 August 2017

B Ma

5

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2 August 2017

R J Riese

6

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2 August 2017

H A Chapman

7

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2 August 2017

S D Shapiro

8

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2 August 2017

J A Elias

9

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2 August 2017

language of work or name

English

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publication date

1 November 2000

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Journal of Clinical Investigation

2 August 2017

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2 August 2017

106

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2 August 2017

1081-1093

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2 August 2017

9

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The importance of shedding of membrane proteins for cytokine biology

2 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301418

Increased susceptibility to pulmonary emphysema among HIV-seropositive smokers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301418

Animal models for chronic obstructive pulmonary disease: age of klotho and marlboro mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301418

Chronic obstructive pulmonary disease. Inflammation of small airways and lung parenchyma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301418

Airway inflammation in chronic obstructive pulmonary disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301418

CD8+ve cells in the lungs of smokers with chronic obstructive pulmonary disease.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301418

The many faces of airway inflammation. Asthma and chronic obstructive pulmonary disease. Asthma Research Group

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301418

Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301418

Interleukin-13: central mediator of allergic asthma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301418

Immunopathology of the small-airway submucosa in smokers with and without chronic obstructive pulmonary disease.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301418

Matrix metalloproteinase-mediated extracellular matrix protein degradation in human pulmonary emphysema.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301418

Airways responsiveness and development and remission of chronic respiratory symptoms in adults.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301418

Regulated overexpression of interleukin 11 in the lung. Use to dissociate development-dependent and -independent phenotypes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301418

Induction of airway mucus production By T helper 2 (Th2) cells: a critical role for interleukin 4 in cell recruitment but not mucus production

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301418

Emerging roles for cysteine proteases in human biology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301418

Membrane protein secretases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301418

Methacholine reactivity predicts changes in lung function over time in smokers with early chronic obstructive pulmonary disease. The Lung Health Study Research Group

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301418

IL-1 and transforming growth factor-beta regulation of fibroblast-derived IL-11.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301418

Pericellular mobilization of the tissue-destructive cysteine proteinases, cathepsins B, L, and S, by human monocyte-derived macrophages

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301418

A prospective longitudinal study of methacholine airway responsiveness as a predictor of pulmonary-function decline: the Normative Aging Study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301418

Effects of the protease inhibitor leupeptin on proteolytic activities and regeneration of mouse skeletal muscles after exercise injuries

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301418

The relationship of nonspecific airway responsiveness and atopy to the rate of decline of lung function. The Normative Aging Study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301418

The Dutch hypothesis (chronic non-specific lung disease) revisited

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301418

Molecular cloning and expression of human alveolar macrophage cathepsin S, an elastinolytic cysteine protease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301418

Rhinovirus regulation of IL-1 receptor antagonist in vivo and in vitro: a potential mechanism of symptom resolution.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301418

Low molecular weight inhibitors in corneal ulceration

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301418

Pitfalls in antiprotease therapy of emphysema.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301418

Matrix metalloproteinase expression and production by alveolar macrophages in emphysema

27 October 2018

1 reference

12 December 2020

Inflammation in bronchial biopsies of subjects with chronic bronchitis: inverse relationship of CD8+ T lymphocytes with FEV1

1 reference

12 December 2020

1 reference

12 December 2020

Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice

1 reference

12 December 2020

IL-4-independent induction of airway hyperresponsiveness by Th2, but not Th1, cells

1 reference

12 December 2020

Receptor for interleukin 13 on AIDS-associated Kaposi's sarcoma cells serves as a new target for a potent Pseudomonas exotoxin-based chimeric toxin protein

1 reference

12 December 2020

The interrelationship of alpha4 integrin and matrix metalloproteinase-2 in the pathogenesis of experimental autoimmune encephalomyelitis

1 reference

12 December 2020

Cysteine proteinases and cystatin C in bronchoalveolar lavage fluid from subjects with subclinical emphysema

1 reference

12 December 2020

Glucocorticoid therapy for chronic obstructive pulmonary disease

1 reference

12 December 2020

Specificity of inhibition of matrix metalloproteinase activity by doxycycline: relationship to structure of the enzyme

1 reference

12 December 2020

Demonstration of the Th1 to Th2 cytokine shift during the course of HIV-1 infection using cytoplasmic cytokine detection on single cell level by flow cytometry

1 reference

12 December 2020

Preoperative treatment with doxycycline reduces aortic wall expression and activation of matrix metalloproteinases in patients with abdominal aortic aneurysms

1 reference

12 December 2020

In vivo and in vitro evidence for the involvement of cysteine proteinases in bone resorption

1 reference

12 December 2020

The definition of emphysema. Report of a National Heart, Lung, and Blood Institute, Division of Lung Diseases workshop

1 reference

12 December 2020

The course and prognosis of different forms of chronic airways obstruction in a sample from the general population

1 reference

12 December 2020

A reexamination of risk factors for ventilatory impairment

1 reference

12 December 2020

Human 92- and 72-kilodalton type IV collagenases are elastases

1 reference

12 December 2020

Activated T-lymphocytes and macrophages in bronchial mucosa of subjects with chronic bronchitis

1 reference

12 December 2020

Cathepsin L activity is increased in alveolar macrophages and bronchoalveolar lavage fluid of smokers

1 reference

12 December 2020

Long-term variability of bronchial responsiveness to histamine in a random population sample of adults

1 reference

12 December 2020

Airway eosinophilia in chronic bronchitis during exacerbations

1 reference

12 December 2020

Airway hyperresponsiveness to histamine associated with accelerated decline in FEV1

1 reference

12 December 2020

Adverse effects of eosinophilia and smoking on the natural history of newly diagnosed chronic bronchitis

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI10458

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2 August 2017

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2 August 2017

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