Gastrin-releasing peptide/neuromedin B receptor antagonists PD176252, PD168368, and related analogs are potent agonists of human formyl-peptide receptors. (Q34458478)

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English	Gastrin-releasing peptide/neuromedin B receptor antagonists PD176252, PD168368, and related analogs are potent agonists of human formyl-peptide receptors.	scientific article

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15 February 2020

Gastrin-releasing peptide/neuromedin B receptor antagonists PD176252, PD168368, and related analogs are potent agonists of human formyl-peptide receptors (English)

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15 February 2020

Andrei I Khlebnikov

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15 February 2020

Igor A Schepetkin

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Igor A Schepetkin

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15 February 2020

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Liliya N Kirpotina

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15 February 2020

Mark A Jutila

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15 February 2020

Mark T Quinn

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13 October 2010

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15 February 2020

Molecular Pharmacology

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15 February 2020

79

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15 February 2020

1

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15 February 2020

77-90

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15 February 2020

Therapeutic anti-inflammatory potential of formyl-peptide receptor agonists

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6 July 2018

Human formyl peptide receptor 2 senses highly pathogenic Staphylococcus aureus

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Are formyl peptide receptors novel targets for therapeutic intervention in ischaemia-reperfusion injury?

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Forced unbinding of GPR17 ligands from wild type and R255I mutant receptor models through a computational approach

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6 July 2018

The annexin I sequence gln(9)-ala(10)-trp(11)-phe(12) is a core structure for interaction with the formyl peptide receptor 1.

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6 July 2018

GPCR 3D homology models for ligand screening: lessons learned from blind predictions of adenosine A2a receptor complex

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6 July 2018

Identification of novel small-molecule agonists for human formyl peptide receptors and pharmacophore models of their recognition.

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6 July 2018

6-methyl-2,4-disubstituted pyridazin-3(2H)-ones: a novel class of small-molecule agonists for formyl peptide receptors

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6 July 2018

International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the formyl peptide receptor (FPR) family

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6 July 2018

Formyl peptide receptors are candidate chemosensory receptors in the vomeronasal organ

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6 July 2018

Analysis of full and partial agonists binding to beta2-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes

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6 July 2018

Identification of novel formyl peptide receptor-like 1 agonists that induce macrophage tumor necrosis factor alpha production.

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6 July 2018

Discovery of Trp-Nle-Tyr-Met as a novel agonist for human formyl peptide receptor-like 1.

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6 July 2018

Antitumor mechanisms of combined gastrin-releasing peptide receptor and epidermal growth factor receptor targeting in head and neck cancer.

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6 July 2018

High-throughput screening for small-molecule activators of neutrophils: identification of novel N-formyl peptide receptor agonists

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6 July 2018

Bombesin receptors as a novel anti-anxiety therapeutic target: BB1 receptor actions on anxiety through alterations of serotonin activity.

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6 July 2018

Structure-activity relationship of for-L-Met L-Leu-L-Phe-OMe analogues in human neutrophils

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6 July 2018

Bombesin/gastrin-releasing peptide receptor antagonists increase the ability of histone deacetylase inhibitors to reduce lung cancer proliferation

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6 July 2018

A novel nonpeptide ligand for formyl peptide receptor-like 1.

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6 July 2018

Identification of peptides that antagonize formyl peptide receptor-like 1-mediated signaling

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6 July 2018

Measurement of NAD(P)H oxidase-derived superoxide with the luminol analogue L-012.

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6 July 2018

Differential activation of formyl peptide receptor-like 1 by peptide ligands

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6 July 2018

Nonpeptide gastrin releasing peptide receptor antagonists inhibit the proliferation of lung cancer cells

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6 July 2018

The neuromedin B receptor antagonist, BIM-23127, is a potent antagonist at human and rat urotensin-II receptors

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6 July 2018

The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints

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6 July 2018

A G protein-coupled receptor responsive to bile acids

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6 July 2018

Phagocyte activation by Trp-Lys-Tyr-Met-Val-Met, acting through FPRL1/LXA4R, is not affected by lipoxin A4

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6 July 2018

Characterization of chenodeoxycholic acid as an endogenous antagonist of the G-coupled formyl peptide receptors

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6 July 2018

Nonpeptide neuromedin B receptor antagonists inhibit the proliferation of C6 cells

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6 July 2018

Tyrosine 220 in the 5th transmembrane domain of the neuromedin B receptor is critical for the high selectivity of the peptoid antagonist PD168368.

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6 July 2018

Comparative pharmacology of the nonpeptide neuromedin B receptor antagonist PD 168368

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6 July 2018

PD 176252--the first high affinity non-peptide gastrin-releasing peptide (BB2) receptor antagonist

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6 July 2018

Cholecystokinin increases intracellular Ca2+ concentration in the Human JURKAT T Lymphocyte cell line

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

Cholecystokinin and the immune system: receptor-mediated chemotaxis of human and rat monocytes

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6 July 2018

N-formylmethionyl peptides as chemoattractants for leucocytes

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Mitochondrial peptides are potent immune activators that activate human neutrophils via FPR-1.

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27 October 2018

The anionic amphiphile SDS is an antagonist for the human neutrophil formyl peptide receptor 1.

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27 October 2018

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27 October 2018

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27 October 2018

Integration of virtual screening with high-throughput flow cytometry to identify novel small molecule formylpeptide receptor antagonists

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27 October 2018

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27 October 2018

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27 October 2018

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27 October 2018

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1 reference

https://pubmed.ncbi.nlm.nih.gov/20943772

12 December 2020

based on heuristic

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Molecular field technology applied to virtual screening and finding the bioactive conformation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20943772

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of human neutrophil functions by sulfated and nonsulfated cholecystokinin octapeptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/20943772

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the Binding Site on the Formyl Peptide Receptor Using Three Receptor Mutants and Analogs of Met-Leu-Phe and Met-Met-Trp-Leu-Leu

1 reference

https://pubmed.ncbi.nlm.nih.gov/20943772

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of inflammation by vasoactive intestinal peptide and bombesin: lack of effects on neutrophil apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20943772

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal transducing properties of the N-formyl peptide receptor expressed in undifferentiated HL60 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20943772

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PMN degranulation in relation to CD63 expression and genetic polymorphisms in healthy individuals and COPD patients

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12 December 2020

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inferred from PubMed ID database lookup

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10.1124/MOL.110.068288

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15 February 2020

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15 February 2020

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15 February 2020

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