IDH1 mutations are common in malignant gliomas arising in adolescents: a report from the Children's Oncology Group (Q34458930)

2 August 2017

title

IDH1 mutations are common in malignant gliomas arising in adolescents: a report from the Children's Oncology Group (English)

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2 August 2017

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7

Peter C Burger

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2 August 2017

Ian F Pollack

1

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2 August 2017

Ronald L Hamilton

2

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2 August 2017

Robert W Sobol

3

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2 August 2017

Marina N Nikiforova

4

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2 August 2017

Maureen A Lyons-Weiler

5

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2 August 2017

William A LaFramboise

6

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2 August 2017

Daniel J Brat

8

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2 August 2017

Marc K Rosenblum

9

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2 August 2017

Emiko J Holmes

10

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2 August 2017

Tianni Zhou

11

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2 August 2017

Regina I Jakacki

12

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2 August 2017

Children's Oncology Group

13

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2 August 2017

publication date

20 August 2010

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2 August 2017

published in

Child's Nervous System

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2 August 2017

volume

27

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2 August 2017

issue

1

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2 August 2017

page(s)

87-94

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Mutant metabolic enzymes are at the origin of gliomas

2 August 2017

cites work

1 reference

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Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

6 July 2018

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IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3014378

Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha

6 July 2018

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IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas

6 July 2018

1 reference

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IDH1 and IDH2 mutations in gliomas

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3014378

IDH1 mutations at residue p.R132 (IDH1(R132)) occur frequently in high-grade gliomas but not in other solid tumors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3014378

Analysis of the IDH1 codon 132 mutation in brain tumors

6 July 2018

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6 July 2018

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The influence of central review on outcome associations in childhood malignant gliomas: results from the CCG-945 experience

6 July 2018

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Age and TP53 mutation frequency in childhood malignant gliomas: results in a multi-institutional cohort.

6 July 2018

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Preferential inactivation of the p53 tumor suppressor pathway and lack of EGFR amplification distinguish de novo high grade pediatric astrocytomas from de novo adult astrocytomas

6 July 2018

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Progression as exemplified by human astrocytic tumors

6 July 2018

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Epidermal growth factor receptor expression and gene amplification in high-grade non-brainstem gliomas of childhood

6 July 2018

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Determination of p53 mutations, EGFR overexpression, and loss of p16 expression in pediatric glioblastomas.

6 July 2018

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Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas

6 July 2018

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Randomized phase III trial in childhood high-grade astrocytoma comparing vincristine, lomustine, and prednisone with the eight-drugs-in-1-day regimen. Childrens Cancer Group.

6 July 2018

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Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures

6 July 2018

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Antigen retrieval in formalin-fixed, paraffin-embedded tissues: an enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections

6 July 2018

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Deregulation of the p14ARF/MDM2/p53 pathway is a prerequisite for human astrocytic gliomas with G1-S transition control gene abnormalities.

6 July 2018

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Analysis of oncogene and tumor suppressor gene alterations in pediatric malignant astrocytomas reveals reduced survival for patients with PTEN mutations.

28 July 2018

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Genetic alterations in pediatric high-grade astrocytomas.

28 July 2018

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Rarity of PTEN deletions and EGFR amplification in malignant gliomas of childhood: results from the Children's Cancer Group 945 cohort

28 July 2018

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https://api.crossref.org/works/10.1007%2FS00381-010-1264-1

Prognostic significance of histological grading, p53 status, YKL-40 expression, and IDH1 mutations in pediatric high-grade gliomas

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3014378

Diagnostic use of IDH1/2 mutation analysis in routine clinical testing of formalin-fixed, paraffin-embedded glioma tissues

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3014378

Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3014378

Combined molecular analysis of BRAF and IDH1 distinguishes pilocytic astrocytoma from diffuse astrocytoma.

27 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3014378

Mutational analysis of IDH1 codon 132 in glioblastomas and other common cancers

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3014378

Expression of p53 and prognosis in children with malignant gliomas.

27 October 2018

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Subsets of glioblastoma multiforme defined by molecular genetic analysis

27 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3014378

The effectiveness of chemotherapy for treatment of high grade astrocytoma in children: results of a randomized trial. A report from the Childrens Cancer Study Group

27 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3014378

An immunochemical analysis of the human nuclear phosphoprotein p53. New monoclonal antibodies and epitope mapping using recombinant p53

27 October 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/20725730

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Brain tumors in children

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20725730

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S00381-010-1264-1

1 reference

Dimensions Publication ID

2 August 2017

0 references

1 reference

2 August 2017

1 reference