Increased mucosal transmission but not enhanced pathogenicity of the CCR5-tropic, simian AIDS-inducing simian/human immunodeficiency virus SHIV(SF162P3) maps to envelope gp120. (Q34464860)

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English	Increased mucosal transmission but not enhanced pathogenicity of the CCR5-tropic, simian AIDS-inducing simian/human immunodeficiency virus SHIV(SF162P3) maps to envelope gp120.	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Increased mucosal transmission but not enhanced pathogenicity of the CCR5-tropic, simian AIDS-inducing simian/human immunodeficiency virus SHIV(SF162P3) maps to envelope gp120. (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

author name string

Mayla Hsu

1

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Janet M Harouse

2

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Agegnehu Gettie

3

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Clarisa Buckner

4

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

James Blanchard

5

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Cecilia Cheng-Mayer

6

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Europe PubMed Central

PubMed publication ID

2 August 2017

language of work or name

0 references

publication date

1 January 2003

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Europe PubMed Central

PubMed publication ID

2 August 2017

Journal of Virology

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Europe PubMed Central

PubMed publication ID

2 August 2017

77

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Europe PubMed Central

PubMed publication ID

2 August 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

989-998

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Addition of a single gp120 glycan confers increased binding to dendritic cell-specific ICAM-3-grabbing nonintegrin and neutralization escape to human immunodeficiency virus type 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140803

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CD4 independence of simian immunodeficiency virus Envs is associated with macrophage tropism, neutralization sensitivity, and attenuated pathogenicity

1 reference

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Primary intestinal epithelial cells selectively transfer R5 HIV-1 to CCR5+ cells

1 reference

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Properties of the surface envelope glycoprotein associated with virulence of simian-human immunodeficiency virus SHIV(SF33A) molecular clones

1 reference

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Rapid and irreversible CD4+ T-cell depletion induced by the highly pathogenic simian/human immunodeficiency virus SHIV(DH12R) is systemic and synchronous

1 reference

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Cytopathicity of human immunodeficiency virus type 1 primary isolates depends on coreceptor usage and not patient disease status

1 reference

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Sensitivity of human immunodeficiency virus type 1 to fusion inhibitors targeted to the gp41 first heptad repeat involves distinct regions of gp41 and is consistently modulated by gp120 interactions with the coreceptor

1 reference

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Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitro

1 reference

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Biologic studies of chimeras of highly and moderately virulent molecular clones of simian immunodeficiency virus SIVsmPBj suggest a critical role for envelope in acute AIDS virus pathogenesis

1 reference

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HIV fusion and its inhibition

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6 July 2018

Membrane-fusing capacity of the human immunodeficiency virus envelope proteins determines the efficiency of CD+ T-cell depletion in macaques infected by a simian-human immunodeficiency virus

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DC-SIGN interactions with human immunodeficiency virus type 1 and 2 and simian immunodeficiency virus

1 reference

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Envelope glycoprotein determinants of neutralization resistance in a simian-human immunodeficiency virus (SHIV-HXBc2P 3.2) derived by passage in monkeys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140803

6 July 2018

Mucosal transmission and induction of simian AIDS by CCR5-specific simian/human immunodeficiency virus SHIV(SF162P3)

1 reference

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6 July 2018

Developments in preclinical AIDS vaccine efficacy models

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The N-terminal V3 loop glycan modulates the interaction of clade A and B human immunodeficiency virus type 1 envelopes with CD4 and chemokine receptors

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Importance of membrane fusion mediated by human immunodeficiency virus envelope glycoproteins for lysis of primary CD4-positive T cells

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Beyond receptor expression: the influence of receptor conformation, density, and affinity in HIV-1 infection

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Sensitivity of human immunodeficiency virus type 1 to the fusion inhibitor T-20 is modulated by coreceptor specificity defined by the V3 loop of gp120

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6 July 2018

Simian-human immunodeficiency virus containing a human immunodeficiency virus type 1 subtype-E envelope gene: persistent infection, CD4(+) T-cell depletion, and mucosal membrane transmission in macaques

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Envelope glycoprotein determinants of increased fusogenicity in a pathogenic simian-human immunodeficiency virus (SHIV-KB9) passaged in vivo

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DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells

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6 July 2018

Pathogenesis of primary R5 human immunodeficiency virus type 1 clones in SCID-hu mice

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6 July 2018

Viral persistence in vivo through selection of neutralizing antibody-escape variants.

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6 July 2018

Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies

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6 July 2018

Fatal immunopathogenesis by SIV/HIV-1 (SHIV) containing a variant form of the HIV-1SF33 env gene in juvenile and newborn rhesus macaques

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6 July 2018

Analysis of the critical domain in the V3 loop of human immunodeficiency virus type 1 gp120 involved in CCR5 utilization

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6 July 2018

R5 strains of human immunodeficiency virus type 1 from rapid progressors lacking X4 strains do not possess X4-type pathogenicity in human thymus.

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6 July 2018

Selection for neutralization resistance of the simian/human immunodeficiency virus SHIVSF33A variant in vivo by virtue of sequence changes in the extracellular envelope glycoprotein that modify N-linked glycosylation.

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6 July 2018

Emerging cytopathic and antigenic simian immunodeficiency virus variants influence AIDS progression.

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HIV: The deadly passenger in dendritic cells

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6 July 2018

Neutralizing antibody directed against the HIV-1 envelope glycoprotein can completely block HIV-1/SIV chimeric virus infections of macaque monkeys.

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6 July 2018

Changes in human immunodeficiency virus type 1 envelope glycoproteins responsible for the pathogenicity of a multiply passaged simian-human immunodeficiency virus (SHIV-HXBc2)

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6 July 2018

Development of a neutralizing antibody response during acute primary human immunodeficiency virus type 1 infection and the emergence of antigenic variants

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The envelope glycoprotein ectodomains determine the efficiency of CD4+ T lymphocyte depletion in simian-human immunodeficiency virus-infected macaques

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Mucosal transmission of pathogenic CXCR4-utilizing SHIVSF33A variants in rhesus macaques

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Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

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6 July 2018

A conserved HIV gp120 glycoprotein structure involved in chemokine receptor binding

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6 July 2018

Evolution of syncytium-inducing and non-syncytium-inducing biological virus clones in relation to replication kinetics during the course of human immunodeficiency virus type 1 infection.

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6 July 2018

In vivo replication capacity rather than in vitro macrophage tropism predicts efficiency of vaginal transmission of simian immunodeficiency virus or simian/human immunodeficiency virus in rhesus macaques.

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6 July 2018

HIV entry and tropism: the chemokine receptor connection.

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6 July 2018

Changes in the extracellular envelope glycoprotein of variants that evolve during the course of simian immunodeficiency virus SIVMne infection affect neutralizing antibody recognition, syncytium formation, and macrophage tropism but not replication,

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6 July 2018

The extent of early viral replication is a critical determinant of the natural history of simian immunodeficiency virus infection

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6 July 2018

Selective employment of chemokine receptors as human immunodeficiency virus type 1 coreceptors determined by individual amino acids within the envelope V3 loop

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Tracking changes in HIV-1 envelope quasispecies using DNA heteroduplex analysis.

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Infection and pathogenicity of chimeric simian-human immunodeficiency viruses in macaques: determinants of high virus loads and CD4 cell killing

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Characterization of molecularly cloned simian-human immunodeficiency viruses causing rapid CD4+ lymphocyte depletion in rhesus monkeys

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Animal model of mucosally transmitted human immunodeficiency virus type 1 disease: intravaginal and oral deposition of simian/human immunodeficiency virus in macaques results in systemic infection, elimination of CD4+ T cells, and AIDS

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Change in coreceptor use correlates with disease progression in HIV-1--infected individuals

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Macrophage tropism of human immunodeficiency virus type 1 and utilization of the CC-CKR5 coreceptor.

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6 July 2018

CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5.

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6 July 2018

CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5.

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6 July 2018

A chimeric simian/human immunodeficiency virus expressing a primary patient human immunodeficiency virus type 1 isolate env causes an AIDS-like disease after in vivo passage in rhesus monkeys.

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Prognosis in HIV-1 infection predicted by the quantity of virus in plasma

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6 July 2018

An env gene derived from a primary human immunodeficiency virus type 1 isolate confers high in vivo replicative capacity to a chimeric simian/human immunodeficiency virus in rhesus monkeys

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6 July 2018

Chimeric simian/human immunodeficiency virus that causes progressive loss of CD4+ T cells and AIDS in pig-tailed macaques

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6 July 2018

Multiple viral determinants contribute to pathogenicity of the acutely lethal simian immunodeficiency virus SIVsmmPBj variant

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6 July 2018

Pathogenesis of human immunodeficiency virus infection

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6 July 2018

Single amino acid change in Tat determines the different rates of replication of two sequential HIV-1 isolates

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6 July 2018

A synthetic peptide from HIV-1 gp41 is a potent inhibitor of virus-mediated cell-cell fusion

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6 July 2018

Prognostic value of HIV-1 syncytium-inducing phenotype for rate of CD4+ cell depletion and progression to AIDS.

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6 July 2018

Persistent infection of rhesus macaques with T-cell-line-tropic and macrophage-tropic clones of simian/human immunodeficiency viruses (SHIV).

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6 July 2018

Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes

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6 July 2018

Human immunodeficiency virus type 1 variants with increased replicative capacity develop during the asymptomatic stage before disease progression

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6 July 2018

Differential syncytium-inducing capacity of human immunodeficiency virus isolates: frequent detection of syncytium-inducing isolates in patients with acquired immunodeficiency syndrome (AIDS) and AIDS-related complex

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6 July 2018

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6 July 2018

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6 July 2018

Rapid development of isolate-specific neutralizing antibodies after primary HIV-1 infection and consequent emergence of virus variants which resist neutralization by autologous sera.

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6 July 2018

Monocytotropic human immunodeficiency virus type 1 (HIV-1) variants detectable in all stages of HIV-1 infection lack T-cell line tropism and syncytium-inducing ability in primary T-cell culture

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6 July 2018

Autologous HIV-1 neutralizing antibodies: emergence of neutralization-resistant escape virus and subsequent development of escape virus neutralizing antibodies

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6 July 2018

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6 July 2018

Immunization of rhesus macaques with a DNA prime/modified vaccinia virus Ankara boost regimen induces broad simian immunodeficiency virus (SIV)-specific T-cell responses and reduces initial viral replication but does not prevent disease progression f

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27 October 2018

Pathogenic determinants of the mucosally transmissible CXCR4-specific SHIV(SF33A2) map to env region

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27 October 2018

Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection

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27 October 2018

Distinct pathogenic sequela in rhesus macaques infected with CCR5 or CXCR4 utilizing SHIVs.

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27 October 2018

Neutralization escape in human immunodeficiency virus type 1-infected long-term nonprogressors

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27 October 2018

Characterization of gut-associated lymphoid tissue (GALT) of normal rhesus macaques

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12 December 2020

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10.1128/JVI.77.2.989-998.2003

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

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